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on page 1 showing 20 out of 83 results from 1 sources

Cite this (Aging Cell Repository, RRID:SCR_007320)

URL: http://ccr.coriell.org/nia/

Resource Type: Resource, database, biomaterial supply resource, biospecimen repository, service resource, storage service resource, cell repository, material storage repository, material resource, data or information resource

A cell repository containing cells and DNA for studies of aging and the degenerative processes associated with it. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer's disease, progeria, Parkinson's disease, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders, as well as DNA from individuals of advanced age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center and other Longevity Collections. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging, and both human and animal differentiated cell types. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research.

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Cite this (Benaroya Research Institute: Neurological Diseases, RRID:SCR_001576)

URL: https://www.benaroyaresearch.org/our-research/clinical-research/currently-enrolling-studies/neurological-disease

Resource Type: Resource, department portal, organization portal, portal, data or information resource

BRI investigators study the molecular and genetic mechanisms which underlie some of the most devastating chronic neurological disorders, and conduct clinical trials for new innovative therapies. Neurological studies that are currently studied include Amyotrophic lateral sclerosis (ALS) or Lou Gehrig's Disease, Multiple Sclerosis, and Parkinson's Disease.

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Cite this (Biobank of Hospital Clinic - IDIBAPS, RRID:SCR_004530)

URL: http://www.clinicbiobanc.org/en_index.html

Resource Type: Resource, organization portal, biomaterial supply resource, tissue bank, service resource, portal, storage service resource, material storage repository, material resource, training service resource, data or information resource

A biobank of repositories which works to obtain, store, manage and distribute large collections of human biological samples of phenotypes and diseases of marked interest for researchers. The biobank sample collection is made up of three extensive repositories. The Neurological Tissue Biobank is a nervous tissue repository (brain and spinal cord) created from donations from cadavers with or without neurological conditions. It helps facilitate research in neurological illnesses. The Tumour Biobank and Anatomical Pathologies Collections is a repository of tumorous tissue and samples from cancer patients. The Blood and Fluid Biobank is a repository which contains samples of metabolic, inflammatory bowel, hepatic, digestive and maternal and foetal diseases, among others. It houses a large range of samples of scientific interest, primarily DNA, serum and plasma.

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Cite this (Brain and Body Donation Program, RRID:SCR_004822)

URL: https://www.bannerhealth.com/research/locations/sun-health-institute/programs/body-donation

Resource Type: Resource, database, biomaterial supply resource, biospecimen repository, tissue bank, service resource, brain bank, storage service resource, data or information resource, material resource, material storage repository

An autopsy-based, research-devoted brain bank, biobank and biospecimen bank that derives its human donors from the Arizona Study of Aging and Neurodegenerative Disease (AZSAND), a longitudinal clinicopathological study of the health and diseases of elderly volunteers living in Maricopa county and metropolitan Phoenix, Arizona. Their function is studied during life and their organs and tissue after death. To date, they have concentrated their studies on Alzheimer's disease, Parkinson's disease, heart disease and cancer. They share the banked tissue, biomaterials and biospecimens with qualified researchers worldwide. Registrants with suitable scientific credentials will be allowed access to a database of available tissue linked to relevant clinical information, and will allow tissue requests to be initiated.

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Cite this (brainfacts.org, RRID:SCR_003514)

URL: http://www.brainfacts.org/

Resource Type: Resource, narrative resource, topical portal, blog, portal, training material, data or information resource

A web portal that aggregates information and educational materials about the brain and brain diseases. Resources such as videos, key brain concepts, and hands-on activities may be used and shared with the public.

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Cite this (Brain Health Registry, RRID:SCR_010230)

URL: http://brainhealthregistry.org/

Resource Type: Resource, people resource, patient registry

A website aimed at recruiting and assessing subjects for all types of neuroscience studies with the internet. The hope is to accelerate various types of observational studies and clinical trials, and also reduce costs. They are interested in having people, including healthy subjects of all ages, join the registry. Joining only takes a few minutes. The web-based project is designed to speed up cures for Alzheimer's, Parkinson's and other brain disorders. It uses online questionnaires and online neuropsychological tests (which are very much like online brain games).

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Cite this (Brain-Net, RRID:SCR_005017)

URL: http://www.brain-net.net/

Resource Type: Resource, biomaterial supply resource, standard specification, narrative resource, brain bank, tissue bank, material resource, data or information resource

A network of several university centers in Germany that classifies neurological and psychiatric disorders neuropathologically and collects and provides brain tissue for research. The aim and task of the Brain-Net are: the collection of clinically and neuropathologically well-characterized brain tissue samples; the standardization of neuropathological diagnoses according to internationally accepted criteria; and providing a basis for future research projects using genetic, epidemiological, biometric and other issues to neurological and psychiatric disorders.

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Cite this (Brain Research Institute Biobank Resources, RRID:SCR_008756)

URL: http://www.bri.ucla.edu/research/resources

Resource Type: Resource, biomaterial supply resource, image collection, tissue bank, brain bank, material resource, data or information resource

Brain bank resources which include postmortem human frozen brain tissue and matched cerebrospinal fluid (CSF) and blood available for scientists to search for etiopathogeneses of human disease. The National Neurological Research Specimen Bank and the Multiple Sclerosis Human Neurospecimen Bank maintains a collection of quick frozen and formalin fixed postmortem human brain tissue and frozen cerebrospinal fluid from patients with neurological diseases, including Alzheimer's Disease, amyotrophic lateral sclerosis, depressive disorder/suicide, and epilepsy, among others. Diagnoses are documented by clinical medical records and gross/microscopic neuropathology. The Neuropathology Laboratory at the UCLA Medical Center maintains a bank of frozen, formalin and paraformaldehyde-fixed and paraffin-embedded postmortem human brain tissues and frozen cerebrospinal fluid (CSF) from patients who die with Alzheimer's disease and other dementing and degenerative illnesses, as well as control materials removed in a similar fashion from patients who are neurologically normal.

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Cite this (Brain Research Institute, RRID:SCR_004988)

URL: http://www.bri.ucla.edu

Resource Type: Resource, topical portal, training resource, graduate program resource, portal, postdoctoral program resource, data or information resource

Portal touching on all aspects of neuroscience from molecules to the mind, from the laboratory bench to the patient's bedside. Members study the normal structure and workings of the nervous system, its development, its cognitive functions, its derangement by disease and injury, and the means of its repair and protection. Projects span traditional disciplinary boundaries, as do graduate and postdoctoral training programs. Its major achievement has been to foster and improve multidisciplinary collaborations which has increasingly permitted the identification of pathogenic mechanisms and the formulation of new therapeutic approaches.

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Cite this (BrainSpan: Atlas of the Developing Human Brain, RRID:SCR_008083)

URL: http://brainspan.org/

Resource Type: Resource, atlas, expression atlas, reference atlas, data or information resource

An atlas of the developing human brain designed as a foundational resource for studying transcriptional mechanisms involved in human brain development. The atlas consists of a variety of data modalities and data mining tools. It contains RNA sequencing and exon microarray data profiling up to sixteen cortical and subcortical structures across the full course of human brain development, as well as high-resolution neuroanatomical transcriptional profiles of about 300 distinct structures spanning the entire brain for four midgestional prenatal specimens. Also included are a high-resolution in situ hybridization image data covering selected genes and brain regions in developing and adult human brain, and a reference atlas in full color with high-resolution anatomic reference atlases of prenatal (two stages) and adult human brain along with supporting histology, magnetic resonance imaging (MRI) and diffusion weighted imaging (DWI) data.

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Cite this (Brown Brain Tissue Resource Center, RRID:SCR_005392)

URL: http://med.brown.edu/neurology/brainbank/index.html

Resource Type: Resource, biomaterial supply resource, brain bank, material resource, tissue bank

A tissue resource center which facilitates research into the relationship between Alzheimer's disease and other brain disorders such as strokes and mental illnesses. Most donations have been obtained from Alzheimer's patients. Normal controls are available, many of which are from subjects with close relatives with Alzheimer's. The Brown BTRC also supports a collection of brain tumor cases that were harvested from patients who underwent surgery and who were enrolled in a clinical trial for the development of new treatments for brain cancer.

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Cite this (CBU Imaging Wiki, RRID:SCR_003014)

URL: http://www.mrc-cbu.cam.ac.uk/Imaging

Resource Type: Resource, topical portal, portal, data or information resource

Portal where neuroimaging studies are carried out using a Siemens 3T Tim Trio Magnetic Resonance Imaging (or MRI) scanner that is wholly dedicated to studies in Cognitive Neuroscience. From emotions and memories to language and learning, functional neuroimaging is being applied in many different areas of Cognitive Neuroscience. In many cases, this research relies upon support from healthy volunteers although neuroimaging studies are also being conducted in various clinical populations, including depression, anxiety, Parkinson's disease and Alzheimer's disease.

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Cite this (Center for Imaging of Neurodegenerative Diseases, RRID:SCR_001968)

URL: http://www.radiology.ucsf.edu/cind

Resource Type: Resource, biomedical technology research center, training resource

Biomedical technology research center that develops and validates new imaging methods for detecting brain abnormalities in neurodegenerative diseases, including Alzheimer's disease, vascular dementia, frontotemporal dementia, Parkinson's disease, as well as epilepsy, depression, and other conditions associated with nerve loss in the brain. As people around the globe live longer, the impact of neurodegenerative diseases is expected to increase further with dire social and economical consequences for societies if no effective treatments are developed soon. The development at CIND is aimed to improve magnetic resonance imaging (MRI). The ultimate goal of the scientific program is to identify imaging markers that improve accuracy in diagnosing neurodegenerative diseases at early stages, achieve more reliable prognoses of disease progression, and facilitate the discovery of effective treatment interventions. In addition to addressing the general needs for studying neurodegenerative diseases, another focus of CIND concerns brain diseases associated with military service and war combat, such as post traumatic stress disorder (PTSD), brain trauma, gulf war illness and the long-term effects of these conditions on the mental health of veterans. The symbiosis between CIND and the Veterans Administration Medical Center in San Francisco makes this program uniquely suited to serve military veterans.

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Cite this (CERAD - Consortium to Establish a Registry for Alzheimer's Disease, RRID:SCR_003016)

URL: http://cerad.mc.duke.edu/

Resource Type: Resource, organization portal, assessment test provider, database, consortium, portal, material resource, data or information resource

Consortium that developed brief, standardized and reliable procedures for the evaluation and diagnosis of patients with Alzheimer's disease (AD) and other dementias of the elderly. These procedures included data forms, flipbooks, guidebooks, brochures, instruction manuals and demonstration tapes, which are now available for purchase. The CERAD assessment material can be used for research purposes as well as for patient care. CERAD has developed several basic standardized instruments, each consisting of brief forms designed to gather data on normal persons as well as on cognitively impaired or behaviorally disturbed individuals. Such data permit the identification of dementia based on clinical, neuropsychological, behavioral or neuropathological criteria. Staff at participating CERAD sites were trained and certified to administer the assessment instruments and to evaluate the subjects enrolled in the study. Cases and controls were evaluated at entry and annually thereafter including (when possible) autopsy examination of the brain to track the natural progression of AD and to obtain neuropathological confirmation of the clinical diagnosis. The CERAD database has become a major resource for research in Alzheimer's disease. It contains longitudinal data for periods as long as seven years on the natural progression of the disorder as well as information on clinical and neuropsychological changes and neuropathological manifestations.

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Cite this (CNSforum: Image Bank, RRID:SCR_002718)

URL: http://www.cnsforum.com/educationalresources/imagebank/

Resource Type: Resource, image collection, data or information resource

A collection of downloadable central nervous system (CNS) images for teaching, presentations, articles, and other purposes. The following major categories of images are as follows: Brain anatomy, Brain physiology, Anxiety, Depression, Schizophrenia, Dementia, Parkinson's disease, Stroke, and Others.

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Cite this (Djavad Mowafaghian Centre for Brain Health, RRID:SCR_013149)

URL: http://brain.ubc.ca/

Resource Type: Resource, topical portal, portal, data or information resource

Research facility for research on neurological and psychiatric disorders on the learning brain and the aging brain. The Centre utilizes a multidisciplinary approach to explore the causes and potential treatments of disorders like Alzheimer's disease, mental health and addiction, stroke and neurotrauma. The Centre focuses on translating research into patient care and therapies.

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Cite this (Emory ADRC Tissue and Biospecimen Banking Facility, RRID:SCR_000551)

URL: http://med.emory.edu/ADRC/research/tissue_biospecimen_banking_facility.html

Resource Type: Resource, biomaterial supply resource, brain bank, material resource, tissue bank

The Alzheimer's Disease Research Center at Emery University maintains an active brain bank to facilitate the acquisition, storage, handling and distribution of well-characterized autopsy brain tissue and other materials to investigators. It contains frozen tissue and brain specimens, formalin fixed tissue, paraformaldehyde fixed tissue, and cryopreserved tissue. The ADRC also has access to tissues and samples related to other neurodegenerative diseases. It contains plasma samples, serum samples, lymphoblast cell lines, and cerebrospinal fluid.

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Cite this (Emory Neurology Database, RRID:SCR_005277)

URL: http://med.emory.edu/ADRC/research/core_neurology_database.html

Resource Type: Resource, data or information resource, database

A database which retains extensive clinical information about study subjects recruited by the Alzheimer's Disease Research Center Clinical Core, as well as other individuals with neurological diseases. In addition to clinical information, the database has basic demographics, medical history (including risk factors such as smoking), and a detailed family history from all subjects. Some entries have neuropsychological measures. Users can access a Summary Database which contains the most commonly requested variables. A data dictionary describing the variables in the Summary Database is available.

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Cite this (Gait Dynamics in Neuro-Degenerative Disease Data Base, RRID:SCR_006979)

URL: http://www.physionet.org/physiobank/database/gaitndd/

Resource Type: Resource, data or information resource, database

Database of records from patients with Parkinson's disease (n = 15), Huntington's disease (n = 20), or amyotrophic lateral sclerosis (n = 13). Records from 16 healthy control subjects are also included here. The raw data were obtained using force-sensitive resistors, with the output roughly proportional to the force under the foot. Stride-to-stride measures of footfall contact times were derived from these signals.

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Cite this (Gait in Aging and Disease Database, RRID:SCR_006886)

URL: http://www.physionet.org/physiobank/database/gaitdb/

Resource Type: Resource, data set, narrative resource, training material, data or information resource

A mini-collection of human gait data that was constructed as a teaching resource for an intensive course (The Modern Science of Human Aging, conducted at MIT) that includes walking stride interval time series from 15 subjects: 5 healthy young adults (23 - 29 years old), 5 healthy old adults (71 - 77 years old), and 5 older adults (60 - 77 years old) with Parkinson's disease. For each subject, two columns of data are included. The first column is time (in seconds) and the second is the stride interval (variously known as stride time, gait cycle duration, and time between successive heel strikes of the same foot). The same data are also available as standard PhysioBank-format annotation (.str) and header (.hea) files, for viewing or analysis using PhysioToolkit software from this site. Subjects walked continuously on level ground around an obstacle-free path. The stride interval was measured using ultra-thin, force sensitive resistors placed inside the shoe. The analog force signal was sampled at 300 Hz with a 12 bit A/D converter, using an ambulatory, ankle-worn microcomputer that also recorded the data. Subsequently, the time between foot-strikes was automatically computed. The method for determining the stride interval is a modification of a previously validated method that has been shown to agree with force-platform measures, a gold standard. Data were collected from the healthy subjects as they walked in a roughly circular path for 15 minutes, and from the subjects with Parkinson's disease as they walked for 6 minutes up and down a long hallway.

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