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on page 1 showing 20 out of 33 results

Cite this (AdaptiveCrawler, RRID:SCR_000573)

URL: http://bsec.ornl.gov/AdaptiveCrawler.shtml

Resource Type: Resource, software resource, data acquisition software, data processing software, software application

A web crawler that can intelligently acquire social media content on the Internet to meet the specific online data source acquisition needs of cancer researchers.

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Cite this (Biobank Graz, RRID:SCR_004245)

URL: http://www.medunigraz.at/en/biobank

Resource Type: Resource, production service resource, analysis service resource, biomaterial supply resource, tissue bank, service resource, material resource, data or information resource

Biobank Graz is a non-profit central Medical University of Graz (MUG) service facility that provides the logistics and infrastructure to optimally support MUG research teams in the collection, processing and storage of biological samples and their associated data. In the course of this, special attention is given to sample and data quality and to the protection of the individual rights of patients. Samples from selected patients at the Graz LKH-University Clinical Centre, who have signed an informed consent declaration, are deposited in Biobank Graz. This means that excess tissue and blood samples are collected and placed in storage. The samples are harvested in the course of routine interventions undertaken by the different departments and institutes of the Graz LKH-University Clinical Centre and approved for use in research projects only after the completion of all necessary laboratory and histopathological analyses. No additional material is removed: in other words, there are no associated drawbacks whatsoever for the patients involved. Biobank Graz operates a quality management system according to ISO 9001:2008 and offers the following services for the processing and storage of biological samples and the handling of data: * Consistently high sample quality through the processing of samples using standardized methods in accordance with written working instructions (SOPs) * Efficient use of resources through the building of shared infrastructure and the development of optimized processes * A high degree of reliability provided by the storage of samples in 24/7 - monitored storage systems. * Processing and storage of all data in accordance with data protection legislation. Biobank Graz comprises both population-based and disease-focused collections of biological materials. It currently contains approx. 3.8 mio samples from approx. 1.2 mio patients representing a nonselected patient group characteristic of central Europe. Because the Institute of Pathology was, until 2003, the exclusive pathology service provider for major parts of the province of Styria, including its capital Graz (population approx. 1.2 mio people), samples from all human diseases, treated by surgery or diagnosed by biopsy, are included in the collection at their natural frequency of occurrence and thus represent cancers and non-cancerous diseases from all organs, and from all age groups. The scientific value of the existing tissue collection is, thus, not only determined by its size and technical homogeneity (all samples have been processed in a single institute under constant conditions for more than 20 years), but also by its population-based character. These features provide ideal opportunities for epidemiological studies and allow the validation of biomarkers for the identification of specific diseases and determination of their response to treatment. Prospectively collected tissues, blood samples and clinical data comprise, on the one hand, randomly selected samples from all diseases and patient groups to provide sufficient numbers of samples for the evaluation of the disease-specificity of any gene or biomarker. On the other hand, Biobank Graz adopts a disease-focused approach for selected diseases (such as breast, colon and liver cancers as well as some metabolic diseases) through the collection of a range of different human biological samples of highest quality and detailed clinical follow-up data. Graz Medical University established the Biobank to provide improved and sustainable access to biological samples and related (clinical) data both for its own academic research and for external research projects of academic and industrial partners. It is a major interest of the university to initiate co-operative research projects. Biological samples and data are available to external institutions performing high-quality research projects which comply with the Biobank''s ethical and legal framework according to the access rules (Contact: COO Karine Sargsyan, MD, PhD).

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Cite this (Biobank Suisse, RRID:SCR_004935)

URL: http://www.biobank-suisse.ch/

Resource Type: Resource, topical portal, database, biomaterial supply resource, service resource, portal, material resource, training service resource, data or information resource

The foundation biobank-suisse (BBS) is a collaborative network of existing and future research biobanks in Switzerland. The primary goals are: 1. to provide researchers a quick overview of available human biospecimens (by using the web query interface) and up to date person related data; and 2. to provide biobankers with services to further improve the quality of biobanks in Switzerland (e.g. information about up-to-date IT and database software for biobanking; solutions for ethical, legal, and social issues; develop common platform for biobankers; etc.). We maintain a database with data about patients and biospecimens. The database can be queried from our web-site. Once the researcher has found suitable biospecimens we will bring him in contact with the biobanks, which have collected the biospecimen. The researcher and the biobank manager will then discuss the next step without further participation of the foundation biobank-suisse. We provide advice and support to biobank manager, who are in the process to start a biobanking activity for material from humans. Well established biobanks can benefit from our help in realizing specific projects to improve their operations. BBS was founded in December 2005 as an initiative of Oncosuisse and SWISS BRIDGE with the goal to build a collaborative network of existing and future biobanks for research in Switzerland. BBS has currently information from about 60 000 biospecimens and 10 000 patients. This information is provided by the biobanks shown under the Partner biobank menu item and include: * Institut de Pathologie, Centre hospitalier universitaire vaudois (CHUV) * Institut f??r Pathologie Universit??tsspital Basel * Institut f??r Pathologie der Universit??t Bern BBS has entered in a closed collaboration with SAKK''s (Swiss Working Group on Clinical Cancer Research) IT department. BBS''s server is run by SAKK and technical support is provided by the SAKK IT department. BBS is an active member of ISBER (International Society of Biological and Environmental Repositories) the international society of biobanks. BBS also joint BBMRI (an European initiative to build an pan-European network of biobanks.

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Cite this (British Columbia Breast Cancer Tumour Bank, RRID:SCR_006671)

URL: http://molonc.bccrc.ca/platforms/btb/

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank, data or information resource

The Molecular Oncology department hosts the breast cancer tumour tissue repository (BREAST-TTR), a project within the agency-wide tumour tissue repository. The BREAST-TTR comprises several important banks of breast tissues, contemporaneous as well as archival. The main banks are: * 3000 frozen breast cancers, linked to 15 year outcomes data from the BCCA Breast Cancer Outcomes Unit. This archival bank consists of frozen tissue, DNA and RNA, and a tissue microarray of the cases. * Live-cryopreserved cancers. At present around 50 individual cases of metastatic breast cancer, with tumour material cryopreserved for subsequent cell culture/xenograft work. * Comptemporary bank. Between the TTR in Victoria and the accrual site in Vancouver, approximately 1300 contemporaneous (within last 4 years) breast cancers with matched normal DNA and outcomes linkages.

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Cite this (Canadian Breast Cancer Foundation Tumor Bank, RRID:SCR_004214)

URL: http://www.abtumorbank.com/

Resource Type: Resource, biomaterial supply resource, biospecimen repository, tissue bank, service resource, storage service resource, data or information resource, material resource, material storage repository

A tumor bank that provides a large collection of cancer specimens, from breast and other cancers, annotated with clinical information. The CBCF TB enables researchers to address unanswered questions concerning the prognosis and treatment of breast cancer and other cancers. The CBCF TB website is also directed to participants interested in donating tumor tissue or blood. Biological specimens such as blood, urine, bone marrow, and ascites (fluid that sometimes collects in the abdomen) contain genetic information, just as tumor tissue does. These samples can be used in studies that may help researchers see how people with certain genetic make-ups respond to certain treatments. It can also explain why different people have different health problems. CBCF TB, formerly ARTB, was created by a merger of components of two existing Tumor-banking initiatives, the CLS Repository in Calgary and the Tumor bank of the PolyomX Program in Edmonton.

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Cite this (Cancer Center Tissue Bank - Fudan University, RRID:SCR_004596)

URL: http://www.shca.org.cn/english/content/11540

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank

The Institutional Tissue Bank (ITB) of Fudan University Shanghai Cancer Center was established in 2006 with the goal of serving as a central repository for human tissue samples for cancer research and possible personalized medicine for the institution. The Institutional Research Board oversees the fulfilling of informed consent of each patient whose samples are collected. The ITB''s collection procedures meet the global quality standards and provide high quality tissue samples. The quality control for morphology, RNA, DNA and protein has been set up to ensure the sample quality. Routine frozen section from tissue aliquot is made for every piece of sample to ensure the component of tumor tissue and the pathological feature is the same as the diagnosed tumor. Agilent 2100 Bioanalyzer was used to provide RNA and DNA quality parameters. The Tissue Bank occupies 500 m2, with sufficient space for sample preparation and storage, data registration, data tracking/access, related equipments and monitor system. Variant samples including blood, tumor tissue, and body fluids are collected and serve as alternative permanent patient tissue records. Annotation of collected samples is captured through linking the medical record and pathological report system to tissue bank software. Frequent tumor types such as lung cancer, breast cancer, gastric cancer, urological tumors, gynecological tumors and esophageal cancers, head & neck cancers, as well as infrequent cancer types such as malignant soft tissue sarcomas, pancreatic cancer, gall bladder cancer, and other rare cancers are all collected and stored. Tumor tissues are stored with matched normal tissues. Serum and plasma are isolated from coagulation plus and coagulation minus blood samples. White blood cells are stored as well. Tissues are stored both in RNALater at -20 degrees C and -80 degrees C after snap frozen. Samples have been increased from 4,000 in 2008 to 10,783 in 2009. To the end of September 2010, over 30,000 samples has been processed and stored in our tissue bank. As planned, 50,000 samples will be stored dynamically. Over 50 funded projects have used the samples from our tissue bank. Productive papers have been published in the past years by using the samples. More and more projects will be approved to get research resources from tissue bank in the future. The tissue bank of FUSCC has been designated as the key subject and successful model by Shanghai municipal government.

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Cite this (Cancer Control using Population-based Registries and Biobanks, RRID:SCR_004902)

URL: http://www.cancerbiobank.org/

Resource Type: Resource, training resource, biomaterial supply resource, standard specification, narrative resource, portal, material resource, data or information resource

CCPRB (Cancer Control using Population-based Registries and Biobanks) is a Network of Excellence project within the sixth framework programme of the European Union. It is aiming at improved control of cancer by facilitating research linking biobanks and cancer registries. The project involves a systematic quality assurance and continuous development of standards and norms for human sample biobanks in Europe, as well as development of improved integrity-protection standards in the handling of sensitive information in connection with biobank-based research. The samples in the biobanks will be used in large-scale cancer research searching for genetic and infectious causes to cancer, in particular in the areas of breast and colorectal cancer and childhood leukemia. Project objectives: * Provide the study base for uniquely large population-based prospective studies on cancer * Define and implement a generally applicable European Quality Standard for Biobanking that will include improved data and specimen standardization, acquisition and analysis, reliable and standardized statistical analysis as well as improved management and co-ordination of European biobanks. * Define and promote the implementation of integrity-proof methods for biobank-based research involving well defined and secure third party code-keeping systems. * Enable large-scale, population-based research on: ** evaluation of cancer treatment and role of molecular markers in treatment selection ** use over-generation registry linkages applied to large biobank cohorts to identify and evaluate genetic predisposition associated with increased cancer risk as well as interactions with common environmental exposures. ** use over-generation registry linkages applied to large biobank cohorts to explore and evaluate intrauterine exposures associated with increased cancer risk ** exploit the power of large population cohorts for design of optimal strategies for cancer prevention and its evaluation. * Establish a Europe-wide network for spreading the awareness of i) the data, samples and knowledge generated European biobank-based research ii) possibilities for future biobank-based research and iii) the best practice quality standards for biobank-based research.

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Cite this (Cancer Registry of Norway, RRID:SCR_008879)

URL: http://www.kreftregisteret.no/en/

Resource Type: Resource, topical portal, database, people resource, patient registry, portal, data or information resource

Comprises 3 registries of cancer patients in Norway: the Incidence Registry, the Clinical Registry and Cancer Statistics. The Incidence Registry contains the basic data items collected from clinicians and pathologists, as well as from administrative discharge and mortality sources. It is updated continuously with information on both new cases, as well as cases diagnosed in previous years. All medical doctors in the country are instructed by law to notify new cancer cases. Clinical Registries: Registration of treatment and follow-up of Norwegian cancer patients. Clinical registries comprehensive registration schemes dedicated to specific cancers have been established to include detailed information on diagnostic measures, therapy, and follow-up. Cancer Statistics: Database of cancer statistics. The Cancer Registry of Norway is maintained by the Institute of Population-based Cancer Research and established in 1951. It is one of the oldest national cancer registries in the world. This, combined with the unique personal identification number used in Norway, makes the Cancer Registry''s data suitable, also internationally; by establishing new knowledge through research and spreading information on cancer.

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Cite this (COLT-Cancer, RRID:SCR_006485)

URL: http://colt.ccbr.utoronto.ca/cancer/

Resource Type: Resource, data analysis service, production service resource, analysis service resource, database, service resource, data or information resource

The COLT-Cancer database is a collection of shRNA dropout signatures profiles, covering ~16000 human genes, and derived from more than 70 Pancreatic, Ovarian and Breast human cancer cell-lines using the microarray detection platform developed in the COLT (CCBR-OICR Lentiviral Technology) facility at the Moffat Lab. All shRNA dropout profiles are freely available through download or queries via this website.

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Cite this (Congressionally Directed Medical Research Program, RRID:SCR_006456)

URL: http://cdmrp.army.mil/

Resource Type: Resource, funding resource

Fund the best research to eradicate diseases and support the warfighter to benefit the American Public. They promote innovative research, recognizing untapped opportunities, creating partnerships, and guarding the public trust. Research Program topics include: * Amyotrophic Lateral Sclerosis * Autism * Bone Marrow Failure * Breast Cancer * Defense Medical Research and Development Program * Duchenne Muscular Dystrophy * Gulf War Illness * Lung Cancer * Multiple Sclerosis * Neurofibromatosis * Ovarian Cancer * Peer Reviewed Cancer * Peer Reviewed Medical * Peer Reviewed Orthopaedic * Prostate Cancer * Psychological Health / Traumatic Brain Injury * Spinal Cord Injury * Tuberous Sclerosis Complex

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Cite this (DCI Tissue and Blood Procurement Shared Resource, RRID:SCR_004116)

URL: http://www.cancer.duke.edu/modules/TissueProcurement29/index.php?id=1

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank

THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 16, 2013. Over 10,000 patient consents, 5,000 banking events, and 40,000 biospecimens have been processed to date with storage of both formalin fixed paraffin embedded (FFPE) tissue and frozen tissue located within multiple freezers spanning temperatures in the range of -80 degrees to -180 degrees C depending on protocol requirements. Considerable effort continues to be expended to assure compliance with IRB, NIH and HIPAA best practices and guidelines on banking human tissues. The biorepository in place today is the result of the combined efforts of the Duke Cancer Institute (DCI) Breast SPORE, DCI Shared Resource for Tissue and Blood Procurement, and the Duke University School of Medicine Research Foundation (DUSOM-RF). The DCI and the School of Medicine Research Foundation (SOMRF) have funded the collection of frozen and fixed tissues, both malignant and benign, under an ?????????????????excess tissue????????????????? protocol that utilizes freshly excised tissue that is available for research after the needs of the pathologic workup are met. This program procures tissues from many anatomic sites including breast. Recently Duke''s Institute of Genome Science & Policy (IGSP), under the direction of Drs. Geoff Ginsburg and Tom Burke, initiated a blood collection program that spans several departments and institutes. The Breast SPORE blood collection program served as the pilot for this much larger effort. The Breast SPORE tissue and blood collection effort utilizes much of the same infrastructure and personnel that are also supported by the DCI, SOMRF, and IGSP.

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Cite this (Eligibility Feature Hierarchy, RRID:SCR_010314)

URL: http://purl.bioontology.org/ontology/ELIG

Resource Type: Resource, ontology, data or information resource, controlled vocabulary

A set of 1,437 eligibility features that were organized into a feature hierarchy using 80 breast cancer trials.

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    GSE1456

Cite this (GSE1456, RRID:SCR_003642)

URL: http://ranchobiosciences.com/gse1456/

Resource Type: Resource, data set, data or information resource

Curated series of expression data for 159 tumors from which RNA could be collected in sufficient amounts and quality for analysis from breast cancer patients. Tissue material was collected from all breast cancer patients receiving surgery at Karolinska Hospital from 1994-1996.

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    GSE20194

Cite this (GSE20194, RRID:SCR_003645)

URL: http://ranchobiosciences.com/gse20194/

Resource Type: Resource, data set, data or information resource

Curated data set of gene expression data from 230 stage I-III breast cancers that were generated from fine needle aspiration specimens of newly diagnosed breast cancers before any therapy. The biopsy specimens were collected sequentially during a prospective pharmacogenomic marker discovery study between 2000 and 2008. These specimens represent 70-90% pure neoplastic cells with minimal stromal contamination. In the study, patients received 6 months of preoperative (neoadjuvant) chemotherapy including paclitaxel, 5-fluorouracil, cyclophosphamide and doxorubicin followed by surgical resection of the cancer.

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    GSE4922

Cite this (GSE4922, RRID:SCR_003557)

URL: http://ranchobiosciences.com/gse4922/

Resource Type: Resource, data set, data or information resource

Curated data set of a study that investigated the expression profiles of 347 primary invasive breast tumors on Affymetrix microarrays. Three separate breast cancer cohorts were analyzed: 1) Uppsala (n=249), 2) Stockholm (n=58), 3) Singapore (n=40). The Uppsala and Singapore data can be accessed in GSE4922. The Stockholm cohort data can be accessed at GEO Series GSE1456.

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    HPA

Cite this (HPA, RRID:SCR_006710)

URL: http://www.proteinatlas.org/

Resource Type: Resource, database, biospecimen repository, service resource, storage service resource, atlas, material storage repository, data or information resource

Public database with millions of high-resolution images showing the spatial distribution of proteins in different normal human tissues and cancer types, as well as different human cell lines. The data is released together with application-specific validation performed for each antibody, including immunohistochemisty, Western blot analysis and, for a large fraction, a protein array assay and immunofluorescent based confocal microscopy. The database has been developed in a gene-centric manner with the inclusion of all human genes predicted from genome efforts. Search functionalities allow for complex queries regarding protein expression profiles, protein classes and chromosome location. Antibodies included have been analyzed using a standardized protocol in a single attempt without further efforts to optimize the procedure and therefore it cannot be excluded that certain observed binding properties are due to technical rather than biological reasons and that further optimization could result in a different outcome. Submission of antibodies: The Swedish Human Proteome Atlas (HPA) program, invites submission of antibodies from both academic and commercial sources to be included in the human protein atlas. All antibodies will be validated by the HPA-program by a standard procedure and antibodies that are accepted will be use in the tissue- profiling program to generate high-resolution immunohistochemistry images representing a wide spectrum of normal tissues and cancer types.

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Cite this (LIBRO-1: Individualized prediction and prevention of breast cancer, RRID:SCR_006036)

URL: http://ki.se/ki/jsp/polopoly.jsp?d=29332&a=103538&l=en

Resource Type: Resource, disease-related portal, topical portal, research forum portal, biomaterial supply resource, portal, material resource, data or information resource

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. Libro-1 is a study with the overall aim to identify prognostic factors for breast cancer. The study comprise women in the Stockholm-Gotland region that were diagnosed with breast cancer between the years 2001-2008. Register data (tumor characteristics and treatment), lifestyle factors and blood samples have been collected from the participants.

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Cite this (LINCS Joint Project - Breast Cancer Network Browser, RRID:SCR_016181)

URL: http://amp.pharm.mssm.edu/LJP/

Resource Type: Resource, software resource, web application

Database application that visualizes signatures from breast cancer cell lines treated with single molecule perturbations such as kinase inhibitors. It represents response similarity using distance between the nodes on its map.

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Cite this (Ludwig Boltzman Tumour Bank, RRID:SCR_004322)

URL: http://toc.lbg.ac.at/en/research-program/project-tumor-bank

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank, data or information resource

As a basis for the experimental cluster projects, and for further future projects a collection of various biological specimens of cancer patients shall be established. All participating Ludwig Boltzmann Institutes (LBIs) are supplying biological specimens from tumor patients and clinical documentation. At the LBI for Gynecology and Gynecologic Oncology a tumor bank for biological specimens from gynecologic cancer patients already exists. All the procedures for sample processing and storage are well established. Existing equipment for storing tissue specimens at -196 degrees C can be used. Materials from the following malignant diseases are collected: Breast cancer Colorectal cancer Neuroendocrine tumors (NET) (Small cell lung cancer (SCLC) and Carcinoid tumors) Types of biological materials: Tissue (fresh frozen) Bone marrow Blood (serum/plasma/cell fractions) Pleural effusions Ascitic fluids Sputum Bronchial lavage Stool The biological specimens are initially processed at the respective LBIs or at their connected lab facilities. Enrichment of blood samples for disseminated tumor cells is done at the LBI for Gynecology and Gynecologic oncology. Long time storage of all materials is done at appropriate temperatures at the same institution. This LBI also coordinates the logistics. All relevant sample-specific and clinical data are surveyed at the respective LBIs and stored centralized in an on-line data bank in anonymized form, respecting all relevant regulations on data protection and security.

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Cite this (Manitoba Breast Tumor Bank, RRID:SCR_008723)

URL: http://umanitoba.ca/institutes/manitoba_institute_cell_biology/MBTB/Index4.htm

Resource Type: Resource, biomaterial supply resource, material resource, tissue bank, data or information resource

A collection of tissue and related clinical data for breast cancer. The Bank stores three types of information on each case within a secure location in CancerCare Manitoba. This information relates to the tissue, clinical, and follow-up information. Tissue information includes the composition of the tissue, the size and type of tumor. Clinical information includes the patient age, clinical symptoms and the results of clinical tests such as x-rays. Follow-up information includes the type of treatment after surgery and the response to this treatment. The Bank provides an important resource both for breast cancer research at the University of Manitoba and for researchers across Canada and internationally. Researchers are charged to cover the costs of storage and release but no tissue or information is sold. The Bank has supported over 50 research studies on breast cancer across North America and Europe. Information is never released from the Bank with any label that might allow it to be traced to an individual. Information is only released as part of a set of anonymized cases, where each case is labeled by an anonymous tumor bank number and consists of a section of tissue with related information. Researchers can apply to study these cases only through a review process and if they obtain approval for their research project from an institutional ethics review board. If approved, researchers are provided with tissue sections and the related clinical information from a set of typically 100 or more ??????cases??????. These cases are carefully selected from the computer database on the basis of selection criteria such as size and type of tumor that are relevant to the research question under study. During the assessment of each breast biopsy specimen small tissue samples are taken by Pathologists to process and examine under a microscope and these samples are then stored as a ??????clinical archive??????. After all diagnosis has been completed the Bank organizes these tissues and related clinical data into ??????cases?????? for both future research and future clinical purposes and stores these ??????cases?????? in CancerCare Manitoba. All cases are distinguished by a Tumor Bank number but are anonymous due to the absence of any tag that might allow it to be traced to an individual patient.

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