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on page 1 showing 20 out of 136 results from 1 sources

    Ablynx

Cite this (Ablynx, RRID:SCR_002940)

URL: http://www.Ablynx.com

Resource Type: Resource, service resource, reagent manufacture, production service resource, material service resource

A biopharmaceutical company engaged in the discovery and development of Nanobodies, a novel class of antibody-derived therapeutic proteins based on single-domain antibody fragments, for a range of serious life-threatening human diseases including inflammation, hematology, oncology and pulmonary disease.

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Cite this (Accelerating Medicines Partnership, RRID:SCR_014927)

URL: https://www.nih.gov/research-training/accelerating-medicines-partnership-amp

Resource Type: Resource, group

Partnership between the National Institutes of Health (NIH), the U.S. Food and Drug Administration (FDA), and multiple biopharmaceutical companies and non-profit organizations whose goal is to increase the number of new diagnostics and therapies for patients and reduce the time and cost of developing them. The group explores three major areas of disease: diabetes, Alzheimer's disease, and rheumatoid arthritis and lupus.

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Cite this (ADNI - Alzheimer's Disease Neuroimaging Initiative, RRID:SCR_003007)

URL: http://adni-info.org/

Resource Type: Resource, service resource, data or information resource, data repository, storage service resource, database

Database of the results of the ADNI study. ADNI is an initiative to develop biomarker-based methods to detect and track the progression of Alzheimer's disease (AD) that provides access to qualified scientists to their database of imaging, clinical, genomic, and biomarker data.

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Cite this (Aging Cell Repository, RRID:SCR_007320)

URL: http://ccr.coriell.org/nia/

Resource Type: Resource, database, biomaterial supply resource, biospecimen repository, service resource, storage service resource, cell repository, material storage repository, material resource, data or information resource

A cell repository containing cells and DNA for studies of aging and the degenerative processes associated with it. Scientists use the highly-characterized, viable, and contaminant-free cell cultures from this collection for research on such diseases as Alzheimer's disease, progeria, Parkinson's disease, Werner syndrome, and Cockayne syndrome. The collections of the Repository include DNA and cell cultures from individuals with premature aging disorders, as well as DNA from individuals of advanced age from the the Baltimore Longitudinal Study of Aging at the Gerontology Research Center and other Longevity Collections. The Repository also includes samples from an Adolescent Study of Obesity, Apparently Healthy Controls, Animal Models of Aging, and both human and animal differentiated cell types. The cells in this resource have been collected over the past three decades using strict diagnostic criteria and banked under the highest quality standards of cell culture. Scientists can use the highly-characterized, viable, and contaminant-free cell cultures from this collection for genetic and cell biology research.

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Cite this (Alzheimer Disease and Frontotemporal Dementia Mutation Database, RRID:SCR_008286)

URL: http://www.molgen.ua.ac.be/ADMutations/default.cfm?MT=1&ML=0&Page=ADMDB

Resource Type: Resource, data or information resource, database

A locus-specific database aimed at collecting known mutations and non-pathogenic coding variations in the genes related to Alzheimer disease (AD) and frontotemporal dementia (FTD), following the guidelines of the Human Genome Variation Society. Mutations can be retrieved based on the gene, phenotype and publication. The database contains mutations reported in the literature and at scientific meetings, and unpublished mutations directly submitted to the database. To date, AD&FTDMDB contains mutations in the genes encoding the Amyloid Beta Precursor Protein (APP), Presenilin 1 (PSEN1), Presenilin 2 (PSEN2), Chromatin Modifying Protein 2B (CHMP2B), fusion (involved in t(12;16) in malignant liposarcoma) (FUS), Granulin (GRN), Microtubule Associated Protein Tau (MAPT), TAR DNA binding protein (TARDBP) and Valosin-containing Protein (VCP) and holds 415 different mutations observed in 1027 patients or families. As of March 2013, the latest publications referenced were from 2008, indicating that this resource may not be up to date.

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Cite this (Alzheimer Europe, RRID:SCR_003802)

URL: http://www.alzheimer-europe.org/

Resource Type: Resource, disease-related portal, topical portal, portal, data or information resource

A non-governmental organization aimed at raising awareness of all forms of dementia by creating a common European platform through co-ordination and co-operation between Alzheimer organizations throughout Europe. Alzheimer Europe is also a source of information on all aspects of dementia.

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Cite this (Alzheimer's and Dementia Resource Center, RRID:SCR_004924)

URL: http://www.adrccares.org/

Resource Type: Resource, disease-related portal, topical portal, biomaterial supply resource, patient-support portal, tissue bank, service resource, brain bank, storage service resource, portal, material storage repository, material resource, data or information resource

The Alzheimer's and Dementia Resource Center (ADRC) facilitates tissue donations for the Brain Bank Research Program in order to help find better treatments, more diagnostic tools and a cure for Alzheimer's disease and dementia. The Brain Bank Program is administered by Mount Sinai Medical Center in Miami Beach and under contract with the Florida Department of Elder Affairs. ADRC also provides caregivers with the educational resources, spiritual comfort and emotional support. The ADRC facilitates training for professional caregivers that meets requirements for the Florida Department of Elder Affairs.

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Cite this (Alzheimer's Disease Cooperative Study, RRID:SCR_008254)

URL: http://www.adcs.org/

Resource Type: Resource, disease-related portal, topical portal, assessment test provider, biomaterial supply resource, tissue bank, portal, material resource, data or information resource

An initiative for Alzheimer's disease clinical studies that works to facilitate the discovery, development and testing of new drugs, and is a part of the Alzheimer's Disease Prevention Initiative. This resource has an emphasis on expanding the range of its patients, mainly by enhancing the recruitment of minority groups. There is a further emphasis placed on testing agents that cannot be patented, as well as developing novel compounds that had been developed by individuals, academic institutions and drug discovery units. This resource also helps in the development of Alzheimer's disease centers to carry out studies, as well as establish administrative, data, operations and medical cores in San Diego. This organization is specifically involved in studies demonstrating the lack of benefit associated, previously used treatments such as: the use of estrogen, non-steroidal anti-inflammatory drugs, B vitamins and a statin drug. The Alzheimer's Disease Cooperative Study also develops assessment instruments to be used in clinical trials. The most frequently used of these tools include: the Alzheimer's Disease Assessment Scale-Cognitive sub-scale (ADAS-cog), Activities of Daily Living (ADL), and the Clinical Global Impression of Change Scale (CGIC). There is also an associated tissue bank at UCSD that includes materials from the clinical trials including: human tissue, blood, plasma, DNA, urine and cerebrospinal fluid.

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Cite this (Alzheimer's Disease Education and Referral Center, RRID:SCR_012787)

URL: https://www.nia.nih.gov/alzheimers

Resource Type: Resource, disease-related portal, topical portal, narrative resource, training material, portal, data or information resource

Portal for Alzheimer's disease that compiles, archives and disseminates information about current treatments, diagnostic tools and ongoing research for health professions, people with AD, their families and the public. The Center provides informational services and referrals for AD symptoms, diagnosis and treatment for patients; clinical trial information and literature searches for researchers; training materials and guidelines for caregivers; and Spanish language resources.

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Cite this (Alzheimer's disease ontology, RRID:SCR_010289)

URL: http://purl.bioontology.org/ontology/ADO

Resource Type: Resource, ontology, data or information resource, controlled vocabulary

An open, public ontology representing relevant knowledge on Alzheimer's disease.

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Cite this (Alzheimer's Foundation of America, RRID:SCR_008724)

URL: http://www.alzfdn.org/index.htm

Resource Type: Resource, disease-related portal, topical portal, portal, funding resource, data or information resource

Non profit organization and informational portal directed towards patients and families. AFA is an umbrella orgnization uniting over 1600 member organizations to collaborate on education, resources, best practices and advocacy. AFA provides several grant opportunities for AFA's nonprofit member organizations and to individuals in need.

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Cite this (Alzheimer Society of Canada, RRID:SCR_000485)

URL: http://www.alzheimer.ca/

Resource Type: Resource, regional funding resource, portal, funding resource, data or information resource

A nonprofit health organization that works to improve the quality of life of Canadians affected by Alzheimer's disease and other dementias. This organization also supports research on the cause and potential cures for the disease through education and funding.

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Cite this (Alzheimer's Plan Foundation, RRID:SCR_004032)

URL: http://www.fondation-alzheimer.org/

Resource Type: Resource, disease-related portal, topical portal, portal, funding resource, data or information resource

A non-profit registered French charity that provides a research on Alzheimer's disease and related disorders program with the following goals: * create a dynamic national and international collaborative research of the fundamental absorptions, * densify the network of public and private researchers with an attractive policy * install infrastructure basic, clinical and laboratory performing research * promote interaction with the health industries to reduce development time. At the national level the Foundation has implemented measures Research Plan, through: * animation fabric French medical and scientific research, * coordination of research initiatives * the implementation of actions, * support for specific projects. Internationally, the Foundation is at the origin of an international mobilization of researchers, initiated during the French Presidency of the European Union. Called Joint Programming, this pilot initiative involves 23 countries will coordinate their efforts at European level research on neurodegenerative diseases, especially Alzheimer's disease.

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Cite this (Alzheimer's Research Forum, RRID:SCR_006416)

URL: http://www.alzforum.org/

Resource Type: Resource, disease-related portal, topical portal, discussion, narrative resource, portal, community building portal, data or information resource

A community building portal dedicated to understanding Alzheimer's disease and related disorders, it reports on the latest scientific findings from basic research to clinical trials, creates and maintains public databases of essential research data and reagents, and produces discussion forums to promote debate, speed the dissemination of new ideas, and break down barriers across disciplines.

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Cite this (Alzheimer's Research UK, RRID:SCR_003847)

URL: http://www.alzheimersresearchuk.org/

Resource Type: Resource, disease-related portal, topical portal, portal, funding resource, data or information resource

The UK's leading dementia research charity that funds world-class, pioneering scientists at leading universities to find preventions, treatments and a cure for dementia.

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    alz.org

Cite this (alz.org, RRID:SCR_007398)

URL: http://www.alz.org/

Resource Type: Resource, disease-related portal, topical portal, portal, funding resource, data or information resource

A non profit organization dedicated to providing support for patients and families with Alzheimer's disease, to educating the public about the disease, to funding a wide range of Alzheimer's disease related research and to finding ways to treat and eventually to prevent Alzheimer's disease. Resources include: the Alzheimer's Association Green-Field Library, a research grants program, and the Journal of the Alzheimer's Association.

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Cite this (AlzProtect, RRID:SCR_000492)

URL: http://www.alzprotect.com/en/

Resource Type: Resource, commercial organization, organization portal, portal, data or information resource

Commercial organization that develops drug candidates in the field of neurodegenerative diseases and particularly Alzheimer's. Their main objective is the development of a drug against Alzheimer's disease from molecules patented by Inserm and the University of Lille II.

  • From Current Category

Cite this (AlzSWAN Knowledge Base, RRID:SCR_003017)

URL: http://hypothesis.alzforum.org/

Resource Type: Resource, portal, knowledge environment, community building portal, knowledgebase, data or information resource

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. A community-driven knowledgebase of Alzheimer disease, in which researchers can annotate scientific claims, data, and information, putting these into the context of testable hypotheses and treatment discovery. This SWAN project adds a collection of hand-curated hypotheses to a research paper, which are then related through a set of discourse relationships. They can be browsed and relations between claims, as well as support networks for a specific claim, are made and visualized. AlzSWAN is where you explore scientific knowledge about Alzheimer disease and share your own ideas, comments and questions in a semantically structured system. AlzSWAN is enabled by Semantic Web technology, a new standard for knowledge organization and transfer on the Web. AlzSWAN organizes and manages knowledge using formal knowledge descriptions called ontologies. Using these formal knowledge descriptions, they can tie statements made in scientific publications or on the Web to scientific evidence, biological terminologies, and knowledgebases, and to claims and counterclaims made by other researchers.

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    Amorfix

Cite this (Amorfix, RRID:SCR_003783)

URL: http://www.amorfix.com/

Resource Type: Resource, commercial organization, organization portal, portal, data or information resource

A product development company focused on therapeutic products and diagnostic devices targeting misfolded protein diseases.

  • From Current Category

Cite this (Avid Radiopharmaceuticals, RRID:SCR_003786)

URL: http://www.avidrp.com/

Resource Type: Resource, commercial organization, organization portal, portal, data or information resource

A subsidiary of Eli Lilly and Company who develops new molecular imaging agents capable of changing the medical management of significant, chronic human diseases by identifying the first stages of pathological change, potentially assisting in earlier diagnosis, and better management and development of new therapies. The company has developed a radioactive tracer called florbetapir (18F). Florbetapir can be used to detect beta amyloid plaques in patients with memory problems using positron emission tomography (PET) scans, making the company the first to bring to market an FDA-approved method that can directly detect this hallmark pathology of Alzheimer's disease. (Wikipedia)

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