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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

(last updated: Aug 3, 2019)

Organism Physical Resource or Software Tool

661,005 Results - per page

DatabaseProper CitationSpeciesNamePhenotypeAvailabilityReferenceNotesAffected GeneGenomic AlterationCatalog IDBackground
MMRRCRRID:MMRRC_000001-UNCMus musculusC57BL/6-Tg(Fga,Fgb,Fgg)1Unc/Mmncabnormal circulating fibrinogen level [MP:0010213]PMID:11521996Research areas: These mice can be bred to other disease models such as ApoE deficient or NOD to determine if hyperfibrinogenemia plays a role in initiation or progression of disease.; Mutation type: TransgeneFga, Fgb, Fgg000001-UNCTransgene
MMRRCRRID:MMRRC_000002-UNCMus musculusB6.129P2-Esr2tm1Unc/Mmncincreased anxiety-related response [MP:0001363], decreased exploration in new environment [MP:0001417], hyporesponsive to tactile stimuli [MP:0005498], abnormal nociception after inflammation [MP:0002736], decreased dopamine level [MP:0005643], abnormal serotonin level [MP:0005322], increased sensitivity to induced morbidity/mortality [MP:0009763], abnormal mammary gland growth during pregnancy [MP:0006269], abnormal myocardial fiber morphology [MP:0000278], abnormal intercalated disc morphology [MP:0006267], enlarged myocardial fiber [MP:0004564], enlarged heart [MP:0000274], increased heart weight [MP:0002833], cardiac hypertrophy [MP:0001625], dilated heart ventricle [MP:0008022], increased vasodilation [MP:0005590], altered response to myocardial infarction [MP:0000343], abnormal enterocyte morphology [MP:0000479], abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842], abnormal enterocyte physiology [MP:0008882], abnormal enterocyte apoptosis [MP:0008884], abnormal enterocyte proliferation [MP:0008883], colitis [MP:0002816], decreased insulin secretion [MP:0003059], decreased circulating glucose level [MP:0005560], increased circulating glucose level [MP:0005559], ascites [MP:0005324], increased insulin sensitivity [MP:0002891], increased urine glycosaminoglycan level [MP:0011473], abnormal response/metabolism to endogenous compounds [MP:0003638], abnormal pulmonary alveolus morphology [MP:0002270], abnormal surfactant physiology [MP:0004782], abnormal muscle contractility [MP:0005620], abnormal urinary bladder morphology [MP:0000538], abnormal urinary bladder urothelium morphology [MP:0000540], abnormal urinary bladder physiology [MP:0010386], urinary bladder inflammation [MP:0009646], long femur [MP:0004348], abnormal long bone epiphyseal plate morphology [MP:0003055], abnormal behavior [MP:0004924], impaired contextual conditioning behavior [MP:0009454], impaired cued conditioning behavior [MP:0009456], abnormal excitatory postsynaptic potential [MP:0002912], reduced long term potentiation [MP:0001473], enlarged pancreatic islets [MP:0009171], abnormal mammary gland growth during lactation [MP:0006270], abnormal mammary gland epithelium morphology [MP:0009504], mammary gland alveolar hyperplasia [MP:0001884], increased body weight [MP:0001260], increased body length [MP:0001257], abnormal auditory brainstem response [MP:0004738], altered response of heart to induced stress [MP:0004484], increased circulating luteinizing hormone level [MP:0001751], decreased physiological sensitivity to xenobiotic [MP:0008874], reproductive system phenotype [MP:0005389], abnormal cumulus oophorus [MP:0009372], prostate gland epithelial hyperplasia [MP:0001167], decreased corpora lutea number [MP:0002680], impaired ovarian folliculogenesis [MP:0001129], anovulation [MP:0008869], decreased ovulation rate [MP:0003355], reduced female fertility [MP:0001923], decreased litter size [MP:0001935], abnormal cochlear IHC afferent innervation pattern [MP:0004746], decreased brain size [MP:0000774], abnormal substantia nigra morphology [MP:0000836], abnormal neocortex morphology [MP:0008547], abnormal somatosensory cortex morphology [MP:0000859], abnormal astrocyte morphology [MP:0002182], astrocytosis [MP:0003354], decreased neuron number [MP:0008948], neuron degeneration [MP:0003224], abnormal leukopoiesis [MP:0005460], abnormal lymphopoiesis [MP:0002401], increased pro-B cell number [MP:0008186], abnormal B cell number [MP:0002458], increased pre-B cell number [MP:0003132], increased leukocyte cell number [MP:0000218], increased granulocyte number [MP:0000322], increased neutrophil cell number [MP:0000219], increased monocyte cell number [MP:0000220], enlarged spleen [MP:0000691], spleen hyperplasia [MP:0000693], spleen hypoplasia [MP:0000694], enlarged lymph nodes [MP:0000702], abnormal vascular smooth muscle morphology [MP:0005592], abnormal vascular smooth muscle physiology [MP:0005595], increased vasoconstriction [MP:0003025], increased systemic arterial blood pressure [MP:0002842], skeleton phenotype [MP:0005390], myelofibrosis [MP:0011747], increased compact bone area [MP:0010967], increased osteoblast cell number [MP:0004988], abnormal bone mineralization [MP:0002896], abnormal muscle electrophysiology [MP:0004145], anemia [MP:0001577], abnormal bone marrow cell number [MP:0000172], increased bone marrow cell number [MP:0000321], increased megakaryocyte cell number [MP:0008254], increased erythrocyte cell number [MP:0003131], increased circulating insulin-like growth factor I level [MP:0004702], behavior/neurological phenotype [MP:0005386], increased aggression towards males [MP:0001354], abnormal spatial learning [MP:0001463], abnormal sexual interaction [MP:0002566], enlarged liver [MP:0000599], abnormal lung morphology [MP:0001175], increased chronic myelocytic leukemia incidence [MP:0005481], increased keratinocyte apoptosis [MP:0009580], abnormal hair cycle catagen phase [MP:0008859], accelerated hair follicle regression [MP:0000392], thin epidermis [MP:0001218]Research areas: Role of estrogen receptors, particularly in relation to the cardiovascular system and bone homeostasis; Mutation type: Targeted MutationEsr2000002-UNCTargeted Mutation
NXRRRID:NXR_0.0001Xenopus laevisAvailableTransgenic Lines0.0001
NXRRRID:NXR_0.0001Xenopus laevisBrainbowHNo longer indexed by source databaseNULL0.0001
NXRRRID:NXR_0.0001Xenopus laevisXla.Tg(thy1-Brainbow1.0H)No longer indexed by source databaseTransgenic Lines0.0001
MMRRCRRID:MMRRC_000011-UCDMus musculusSTOCK Mecp2tm1.1Jae/Mmucdataxia [MP:0001393], hypoactivity [MP:0001402], increased susceptibility to age related obesity [MP:0003212], abnormal breathing pattern [MP:0001951], tachypnea [MP:0005426], apnea [MP:0001957], decreased body weight [MP:0001262], decreased brain weight [MP:0002175]References (2)Research areas: Rett Syndrome Research Foundation; Mutation type: Targeted MutationMecp2000011-UCDTargeted Mutation
MMRRCRRID:MMRRC_000012-UNCMus musculusB6.129P2-Ccr2tm1Mae/Mmncretinal photoreceptor degeneration [MP:0008450], abnormal retinal pigment epithelium morphology [MP:0005201], retinal outer nuclear layer degeneration [MP:0008518], retinal degeneration [MP:0001326], retinal deposits [MP:0006187], abnormal optic choroid morphology [MP:0005098], abnormal choriocapillaris morphology [MP:0006238], choroidal neovascularization [MP:0005546], abnormal Bruch membrane morphology [MP:0005239], alcohol aversion [MP:0002570], decreased alcohol consumption [MP:0003546], increased fluid intake [MP:0011941], increased alcohol consumption [MP:0003545], abnormal conditioned taste aversion behavior [MP:0002805], decreased macrophage cell number [MP:0003884], increased IgG level [MP:0002493], lipofuscinosis [MP:0008842], abnormal leukocyte migration [MP:0003156], impaired macrophage chemotaxis [MP:0003799], abnormal chemokine secretion [MP:0008722], decreased neutrophil cell number [MP:0000222], abnormal leukocyte physiology [MP:0002442], decreased circulating creatinine level [MP:0005554], decreased susceptibility to kidney reperfusion injury [MP:0004042], weight loss [MP:0001263], increased susceptibility to induced colitis [MP:0008537], increased B cell number [MP:0005014], decreased CD4-positive, alpha beta T cell number [MP:0008075], increased CD8-positive, alpha-beta T cell number [MP:0008078], abnormal cytokine secretion [MP:0003009], decreased inflammatory response [MP:0001876], diarrhea [MP:0005036]PMID:9342361Research areas: Inflammation, Role of chemokines in chronic disease development, Macrophage biology; Mutation type: Targeted MutationCcr2000012-UNCTargeted Mutation
MMRRCRRID:MMRRC_000013-UNCMus musculusB6.129P2-Npr1tm1(Npr1)Unc/Mmncdecreased systemic arterial blood pressure [MP:0002843], increased circulating testosterone level [MP:0002781], abnormal sex gland physiology [MP:0005647]PMID:9482923Mutation type: Targeted MutationNpr1000013-UNCTargeted Mutation
MMRRCRRID:MMRRC_000014-UCDMus musculusB6;129P2-Tk1tm1Vnd/Mmucdpartial postnatal lethality [MP:0011086], premature death [MP:0002083], arteriosclerosis [MP:0003991], arteritis [MP:0010138], pancreatic acinar cell zymogen granule accumulation [MP:0009161], abnormal sublingual gland morphology [MP:0004035], decreased pancreatic islet number [MP:0009168], small pancreas [MP:0004247], thyroid inflammation [MP:0003504], small spleen [MP:0000692], spleen hypoplasia [MP:0000694], hemosiderosis [MP:0005639], abnormal lymph node morphology [MP:0002339], liver inflammation [MP:0001860], lung inflammation [MP:0001861], hunched posture [MP:0001505], abnormal locomotor behavior [MP:0001392], abnormal nephron morphology [MP:0003881], glomerulosclerosis [MP:0005264], abnormal spermatogenesis [MP:0001156], abnormal epididymis morphology [MP:0002631], reduced fertility [MP:0001921], abnormal bronchiole morphology [MP:0002267], no abnormal phenotype detected [MP:0002169]PMID:8991081Research areas: In vivo mutation detection - Tk+/- animals are useful as a model for in vivo mutation detection in an endogenous autosomal gene. They are an in vivo analog of mouse lymphoma cells L5178YTk+/- widely used for mutation studies. Tk-/- (KO) animals can be used to determine biological significance of thymidine kinase deficiency and salvage pathway of nucleotide synthesis. Also they can be a model of kidney failure due to unidentified cause.; Mutation type: Targeted MutationTk1000014-UCDTargeted Mutation
MMRRCRRID:MMRRC_000015-UCDMus musculusB6.129P2-Gulotm1Mae/Mmucdpremature death [MP:0002083], weight loss [MP:0001263], postnatal growth retardation [MP:0001732], anemia [MP:0001577], decreased erythrocyte cell number [MP:0002875], decreased hematocrit [MP:0000208], decreased mean corpuscular hemoglobin [MP:0005562], abnormal aorta endothelium morphology [MP:0009864], abnormal aorta elastic tissue morphology [MP:0009862], abnormal aorta smooth muscle morphology [MP:0009865], hemorrhage [MP:0001914], gastrointestinal hemorrhage [MP:0000465], increased vascular permeability [MP:0003070], decreased circulating HDL cholesterol level [MP:0000186], increased circulating cholesterol level [MP:0005178], abnormal vitamin C level [MP:0011229], joint swelling [MP:0002936]PMID:10639167Research areas: Cancer, Cardiovascular diseases, Diabetes, Inflammation, Bone matrix biology; Mutation type: Targeted MutationGulo000015-UCDTargeted Mutation
MMRRCRRID:MMRRC_000016-UNCMus musculusB6;129-Npr3tm1Unc/Mmncpartial postnatal lethality [MP:0011086], increased erythrocyte cell number [MP:0003131], increased hematocrit [MP:0002608], increased hemoglobin content [MP:0005564], abnormal osteoclast morphology [MP:0004982], abnormal blood homeostasis [MP:0009642], increased circulating alkaline phosphatase level [MP:0002968], dehydration [MP:0001429], abnormal urine nucleotide level [MP:0011476], decreased urine osmolality [MP:0002988], hypovolemia [MP:0010128], hypotension [MP:0001596], polyuria [MP:0001762], polydipsia [MP:0001426], hunched posture [MP:0001505], decreased body weight [MP:0001262], increased body length [MP:0001257], domed cranium [MP:0000440], increased length of long bones [MP:0004695], elongated metatarsal bones [MP:0004641], small thoracic cage [MP:0010103], elongated vertebral body [MP:0004705], increased osteoblast cell number [MP:0004988], abnormal bone trabecula morphology [MP:0010867], abnormal skeleton development [MP:0002113], abnormal long bone epiphyseal plate proliferative zone [MP:0003662], delayed bone ossification [MP:0000060], abnormal bone remodeling [MP:0002998], long tail [MP:0002758], reduced fertility [MP:0001921]PMID:10377427Research areas: Bone metabolism, Cardiovascular studies; Mutation type: Targeted MutationNpr3000016-UNCTargeted Mutation
MMRRCRRID:MMRRC_000017-UCDMus musculusB6.129S-Slc12a1tm1Tkh/Mmucdcomplete postnatal lethality [MP:0011085], postnatal growth retardation [MP:0001732], increased hematocrit [MP:0002608], abnormal blood homeostasis [MP:0009642], increased circulating creatinine level [MP:0005553], decreased circulating glucose level [MP:0005560], increased circulating sodium level [MP:0005633], increased circulating total protein level [MP:0005568], abnormal fluid regulation [MP:0001784], increased circulating chloride level [MP:0003019], acidosis [MP:0003031], increased urine calcium level [MP:0005441], increased renin activity [MP:0005582], abnormal kidney morphology [MP:0002135], hydronephrosis [MP:0000519], abnormal renal tubule morphology [MP:0002703], nephrocalcinosis [MP:0003197], abnormal kidney physiology [MP:0002136], kidney failure [MP:0003606], polyuria [MP:0001762], decreased skin turgor [MP:0003653]PMID:10779555Research areas: Polyuria, Bartter's Syndrome, Water and electrolyte metabolism of the kidney; Mutation type: Targeted MutationSlc12a1000017-UCDTargeted Mutation
MMRRCRRID:MMRRC_000018-MUMus musculusC57BL/6-Tg(Fga,Fgb,Fgg)2Unc/MmmhPMID:11521996Research areas: Cardiovascular, Hematology, Research Tools, Models fro Human Disease, hyperfibrinogenemia; Mutation type: TransgeneFga, Fgb, Fgg000018-MUTransgene
MMRRCRRID:MMRRC_000019-UCDMus musculusB6.129(Cg)-Atox1Gt(IRESBetageo)3Pgr/Mmucdpartial neonatal lethality [MP:0011088], partial postnatal lethality [MP:0011086], decreased body size [MP:0001265], postnatal growth retardation [MP:0001732], hypoactivity [MP:0001402], seizures [MP:0002064], hypopigmentation [MP:0005408], internal hemorrhage [MP:0001634], pulmonary alveolar hemorrhage [MP:0010909], decreased body temperature [MP:0005534], abnormal copper homeostasis [MP:0003951], decreased brain copper level [MP:0011215], decreased liver copper level [MP:0003067], abnormal enzyme/coenzyme activity [MP:0005584], maternal effect [MP:0003718], microphthalmia [MP:0001297], abnormal nervous system morphology [MP:0003632], loose skin [MP:0005421]PMID:11391006Research areas: Developmental Biology; Mutation type: Gene TrapAtox1000019-UCDGene Trap
NXRRRID:NXR_0.0002Xenopus laevisAvailableTransgenic Lines0.0002
NXRRRID:NXR_0.0002Xenopus laevisXla.Tg(thy1-Brainbow1.0L)No longer indexed by source databaseTransgenic Lines0.0002
NXRRRID:NXR_0.0002Xenopus laevisBrainbowLNo longer indexed by source databaseNULL0.0002
MMRRCRRID:MMRRC_000020-MUMus musculusB6;129-Traf4tm1Lind/Mmmhdecreased body weight [MP:0001262], lung inflammation [MP:0001861], abnormal tracheal cartilage morphology [MP:0003120], trachea stenosis [MP:0010883], stridor [MP:0013752], immune system phenotype [MP:0005387]PMID:10934170Research areas: Pulmonary Inflammation - Knockout mice provide a very precise model for the effects of upper tracheal constriction and could be useful both as a developmental model and a model for pulmonary inflammation.; Mutation type: Targeted MutationTraf4000020-MUTargeted Mutation
MMRRCRRID:MMRRC_000021-MUMus musculusB6.129-Xiaptm1Thsn/Mmmhno abnormal phenotype detected [MP:0002169]PMID:11313486Research areas: Even though Birc4tm1Thsn (XIAP) knock-out mice have no obvious defects, probably due to compensatory increases in levels of other IAP family members, it remains a useful in vivo model to validate in vitro observations; Mutation type: Targeted MutationXiap000021-MUTargeted Mutation
MMRRCRRID:MMRRC_000022-UCDMus musculusSTOCK Mafbm1Gsb/Mmucdabnormal endocrine pancreas development [MP:0011932]PMID:8001130Research areas: Developmental Biology, Brain Dysmorphology; Mutation type: Chemically InducedMafb000022-UCDChemically Induced
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