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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

(last updated: Aug 3, 2019)

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990 Results - per page

DatabaseProper CitationSpeciesNamePhenotypeAvailabilityReferenceNotesAffected GeneGenomic AlterationCatalog IDBackground
MGIRRID:MGI:5285627Mus musculusSlc6a3tm1(cre)Xz/Slc6a3+hyperactivityAvailability unknown check source stock centerPMID:21795541Allele Detail: TargetedSlc6a3tm1(cre)Xz5285627involves: 129S1/Sv
RGDRRID:RGD_61000Rattus norvegicusSHR Spontaneously Hypertensive Ratabnormal cardiac stroke volume, abnormal response to new environment, hyperactivity, increased circulating glucose level, increased systemic arterial blood pressureliveReferences (2)Okamoto 1963 from outbred Wistar Kyoto rats. Bred from a male with mild hypertension, mated with a female with high blood pressure. Brother x sister mating with continued selection for high blood pressure (Okamoto 1969, Okamoto et al 1972). A number of sublines have been developed with a tendency to develop cardiovascular lesions and stroke (see particularly SHRSP) (Nagaoka et al 1976), and hypercholesterolemia (Yamori 1984). For a recent review see Yamori, (1994). However, there is no evidence for substrain differentiation among SHR stocks from the major commercial suppliers in the USA both respect to phenotype and DNA fingerprints (Blizard et al, 1991). Strain WKY, developed from the same base populations is sometimes used as a normotensive control, though its use as such must be questioned as it differs at many genetic marker loci (Festing and Bender 1984, and see also strain WKY). Stelzin et al (1992) found that SHR and WKY shared only 50% of their DNA fingerprint bands, whereas SS and SR shared about 80% of bands. Most authorities suggest that WKY alone is not a good control strain, and that for most comparative studies several normotensive strains should be used. There is an extensive literature on the characteristics of SHR. DeJong (1984) provides a useful comparative review of this and other hypertensive strains, and there are regular symposia on hypertensive rat strains (see J. Hypertension 4(suppl):S1-S541, 1986, and Jpn. Heart J. 28:567-648).61000inbred strain
MGIRRID:MGI:4358085Mus musculusKalrntm1Ppen/Kalrn+hyperactivityAvailability unknown check source stock centerPMID:19625617Allele Detail: TargetedKalrntm1Ppen4358085Not Specified
MGIRRID:MGI:6263663Mus musculusTecpr2em1(IMPC)J/Tecpr2em1(IMPC)Jabnormal behavior, hyperactivity, increased vertical activityAvailability unknown check source stock centerAllele Detail: Endonuclease-mediatedTecpr2em1(IMPC)J6263663C57BL/6NJ-Tecpr2/Mmjax
MGIRRID:MGI:5757833Mus musculusTspyl2tm1b(KOMP)WtsihyperactivityAvailability unknown check source stock centerAllele Detail: TargetedTspyl2tm1b(KOMP)Wtsi5757833C57BL/6N-Tspyl2/Wtsi
MGIRRID:MGI:3702109Mus musculusUnc79Lwt/Unc79+hyperactivityAvailability unknown check source stock centerPMID:16436185Allele Detail: Chemically induced (ENU)Unc79Lwt3702109involves: C57BL/6J * DBA/2J
MGIRRID:MGI:6262795Mus musculusLefty1tm1b(KOMP)Wtsi/Lefty1+increased circulating potassium level, abnormal gait, hyperactivityAvailability unknown check source stock centerAllele Detail: TargetedLefty1tm1b(KOMP)Wtsi6262795C57BL/6N-Lefty1/Bay
MGIRRID:MGI:3040241Mus musculusCocia8C57BL/6JhyperactivityAvailability unknown check source stock centerPMID:12777963Allele Detail: QTLCocia8C57BL/6J3040241involves: A/J * C57BL/6J
MGIRRID:MGI:6263790Mus musculusTspyl2tm1b(KOMP)Wtsi/Tspyl2tm1b(KOMP)WtsihyperactivityAvailability unknown check source stock centerAllele Detail: TargetedTspyl2tm1b(KOMP)Wtsi6263790C57BL/6N-Tspyl2/Wtsi
MGIRRID:MGI:3027200Mus musculusnur3/nur3abnormal craniofacial morphology, hyperactivityAvailability unknown check source stock centerPMID:12955145Allele Detail: Chemically induced (ENU)nur3nur33027200Not Specified
MGIRRID:MGI:3606457Mus musculusGria4tm1Dgen/Gria4tm1Dgenabnormal seizure response to pharmacological agent, increased thermal nociceptive threshold, hyperactivityAvailability unknown check source stock centerAllele Detail: TargetedGria4tm1Dgen3606457involves: 129P2/OlaHsd * C57BL/6
MGIRRID:MGI:6288374Mus musculusCcdc114tm2b(EUCOMM)Wtsi/Ccdc114+increased cardiac muscle contractility, hyperactivity, abnormal behaviorAvailability unknown check source stock centerAllele Detail: TargetedCcdc114tm2b(EUCOMM)Wtsi6288374C57BL/6N-Ccdc114/Bay
RGDRRID:RGD_4891165Rattus norvegicusWig/Ymas wigglinghyperactivitylivePMID:17610585These are congenic wiggling rats established by transferring the wiggling gene from Long-Evans Cinnamon (LEC) to Wistar King-Aptekman/Hokkaido (WKAH) strain Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan4891165congenic strain
MGIRRID:MGI:3040240Mus musculusCocia7C57BL/6JhyperactivityAvailability unknown check source stock centerPMID:12777963Allele Detail: QTLCocia7C57BL/6J3040240involves: A/J * C57BL/6J
RGDRRID:RGD_11528588Rattus norvegicusSHR.LEW-(D4Rat76-D4Mgh11)enhanced active avoidance behavior, hyperactivity, impaired passive avoidance behaviorlivePMID:24386249This congenic strain contains a LEW chromosome 4 segment containing a QTL affecting anxiety-related response transferred to the SHR background. Laboratorio de Genetica do Comportamento, Departamento de Biologia Celular, Embriologia e Genetica, Centro de Ciencias Biologicas, Universidade Federal de Santa Catarina, Florianopolis, Santa Catarina, Brazil11528588congenic strain
MGIRRID:MGI:5502739Mus musculusKcnh1tm1.1Ruf/Kcnh1tm1.1Rufabnormal behavior, hyperactivity, nervous system phenotypeAvailability unknown check source stock centerPMID:23424202Allele Detail: TargetedKcnh1tm1.1Ruf5502739involves: 129 * C57BL/6N
MGIRRID:MGI:6263425Mus musculusSaxo1tm1b(EUCOMM)Hmgu/Saxo1tm1b(EUCOMM)Hmguabnormal behavior, hyperactivityAvailability unknown check source stock centerAllele Detail: TargetedSaxo1tm1b(EUCOMM)Hmgu6263425C57BL/6N-Saxo1/Ics
RGDRRID:RGD_1641877Rattus norvegicusNP.P-(D4Rat119-D4Rat55)/Iusmdecreased body weight, hyperactivity, increased alcohol consumption, increased bone mineral densityliveReferences (2)Male P and female NP rats were backcrossed to get F1 animals which were further backcrossed to NP rats for 10 generations, this was followed by intercross to generate the congenic strains, these animals were selected by marker-assisted selection Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana1641877congenic strain
MGIRRID:MGI:5792339Mus musculusAp2b1mpc187H/Ap2b1mpc187HhyperactivityAvailability unknown check source stock centerPMID:27534441Allele Detail: Chemically induced (ENU)Ap2b1mpc187H5792339involves: BALB/c * C3H/HeH * C57BL/6J
MGIRRID:MGI:5660867Mus musculusNlgn3tm4.1Sudhyperactivity, enhanced learningAvailability unknown check source stock centerPMID:24995986Allele Detail: TargetedNlgn3tm4.1Sud5660867involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
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