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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.

(last updated: Aug 3, 2019)

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2,241 Results - per page

DatabaseProper CitationSpeciesNamePhenotypeAvailabilityReferenceNotesAffected GeneGenomic AlterationCatalog IDBackground
TSCRRID:TSC_SD01994Tetrahymena thermophila∆H3 all, gl KO, M7-6Germline heteokaryon for all three H3 genes(major and minor) and H4II, neo cassette.It is mating type VI Note: now know there is a HHT4 which was still present. From the Gorovsky lab, University of Rochester.HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170)Micronucleus: Neo3 KO of HHT!,HHT2/HHF2,HHT3SD01994hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; hht3[∆::neo2]/hht3[∆::neo2]; mpr1-1/mpr1-1 (pm-s, mp-r, wt HHT1,2,3 HHF2, VII)
TSCRRID:TSC_SD01625Tetrahymena thermophilaB2086 IIPMID:8253268All three B2086 clones were used extensively for crosses in the Frankel lab in the late 1980's and 1990's. Submitted by Joseph Frankel, University of IowaSD01625mat1-2/mat1-2 (mat1-2, II)
TSCRRID:TSC_SD02879Tetrahymena thermophilaXLT22References (2)CET of CU428 x B2086 with plamid XL202, HTA2 with neo2 cassette replacing coding From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500), HTA3 (TTHERM_00143660)SD02879(?)
TSCRRID:TSC_SD02647Tetrahymena thermophilaHA-hv2 (8)References (2)HA-tagged hv2 transformant. Checked by western blot and immunofluorescent staining From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HHT3 (TTHERM_00016170)Macronucleus: N-terminal HA tag of HHT3, not sure if complete replacementSD02647mpr1-1/mpr1-1 (?HHT3/hht3[3’neo2, HAn]; pm-r, VII)
TSCRRID:TSC_SD02457Tetrahymena thermophilaHTA3-T42E1References (2)G304A1xG311A1 ∆HTA3 knockout heterokaryon. Rescued with HTAZ mutated K130R. no ubiquitination of H2AF/Z. From the Gorovsky lab, University of Rochester.HTA3 (TTHERM_00143660)Micronucleus: Neo2 in HTAZ Macronucleus: HTAZ coding replaced with mutation K130RSD02457htaz[∆::neo2]/htaz[∆::neo2]; mpr1-1/MPR1-1? (htaz[∆::neo2]/htaz[K130R]; pm-r)
TSCRRID:TSC_SD02145Tetrahymena thermophilaGTU-TAP (3)PMID:12356864Rescue of GTU05XGTU06 knockout heterokaryons with pTTMG-HA TAP. GTU1 with HA+TAP tag into MTT1 locus. MTT1 promoter, grow with 0.2ug/ml CdCl in 1xSPP. 5’MTT1-GTU-HA-TAP-MTT1 3’ TAP tag from Eric Phzicky is: GTU-HA-6XHis-3Cprotease cleavage-S.Aureus protein A. Constuct pTTMG-HA used to rescue GTU5 xGTU06 KO heterokaryons. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.GTU1 (TTHERM_00079520)Micronucleus: neo2 Macronucleus: Into MTT1 locus, GTU1 with HA and TAP tagSD02145gtu1[∆::neo2]/ gtu1[∆::neo2] (gtu1[∆::neo2]; MTT1/mtt1[∆, (::GTU-HA-TAP]; pm-r, ?)
TSCRRID:TSC_SD02990Tetrahymena sp?19769-1PMID:24885485Collected by Paul Doerder on 7/20/2008 from the lake designated Lake Gaston 2 in NC (latitude 36.52, longitude -77.88) It is amicronucleate.SD02990
TSCRRID:TSC_SD01841Tetrahymena thermophilaBTU1-E431,432,435DReferences (2)Progeny of DB6B x DB2A, transformed by BTU1-1235D mutation construct (E431,432, 435D). The strain was supposed to be pm-r, but the thawed line is pm-s. From the Gorovsky lab, University of Rochester.BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580)Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: BTU1 has only (E431,432,435D) no WT BTU2 is KOSD01841btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-? [E431D,E432D,E435D])
TSCRRID:TSC_SD01362Tetrahymena thermophilagl∆H3/H4 major, #7PMID:15701804Germline heteokaryon Major H3 and H4 genes knocked out with neo cassette.It mates with gl∆H3/H4 #4 strain. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HHT + HHF (TTHERM_00570560, TTHERM_00189180, TTHERM_00189170)Micronucleus: Neo KO of all major HHT genes and HHF genesSD01362hhf1[∆::neo1]/hhf1[∆::neo1]; hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; (mp-r, VII)
TSCRRID:TSC_SD02718Tetrahymena thermophilaRPA5-HA-8PMID:15470252All Somatic copy of RPA5 was replaced with RPA5-HA construct, neo3, CU428background. RPA5 is the fifth largest subunit of pol I and III. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.RPC5 (TTHERM_00094210)Macronucleus: HA tagged RPC5SD02718mpr1-1/mpr1-1 (rpc5[3’neo3,HAc]; pm-r, VII)
TSCRRID:TSC_SD01842Tetrahymena thermophilaBTU1-E431,435DReferences (2)Progeny of DB6B x DB2A, transformed by BTU1-1235D mutation construct (E431,435D) From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.BTU1 (TTHERM_00348510), BTU2 (TTHERM_00836580)Micronucleus: knockout of btu1 with neo knockout of btu2 with bsr Macronucleus: BTU1 has only (E431,435D) no WT BTU2 is KOSD01842btu1-?[∆::neo1]/ btu1-?[∆::neo1]; btu2-?[∆::bsr1]/ btu2-?[∆::bsr1]; CHX1/CHX1; mpr1-1/mpr1-1 or MPR1/MPR1 (btu2-?[∆::bsr1]; btu1-?[∆::neo1]/ btu1-? [E431D,E435D]; pm-r, BTUI has(E431,435D), BTU2 is replaced by bsr1)
TSCRRID:TSC_SD02084Tetrahymena thermophilahtb1-A1G-A9bPMID:19822522∆∆HTB knockout heterokaryons rescued by htb1-A1G. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HTB1 (TTHERM_00633360), HTB2 (TTHERM_00283180)Micronucleus: neo2 KO of HTB1 and HTB2 coding Macronucleus: Mutated HTB1 with A1GSD02084htb1[∆::neo2]/htb1[∆::neo2]; htb2 [∆::neo2]/htb2 [∆::neo2] (htb1[∆::neo2]/htb1[A1G] ; htb2 [∆::neo2]; pm-r, ?)
TSCRRID:TSC_SD01419Tetrahymena thermophilaTTMN CU428PMID:11891286CU428 transformed by pTTMN construct and cells selected with 10 mg/ml paromomycin. Partially replaced. Still has wt Metallothionein gene copies in mac as well as other alleles with neo coding.MTT1 (TTHERM_00241640)Macronucleus: Neo coding replaces MTT1 coding of some of MTT1 copies, both presentSD01419mpr1-1/mpr1-1 (pm-r, VII)
TSCRRID:TSC_SD01723Tetrahymena thermophilaSB2031PMID:1499157Submitted by Eileen Hamilton, University of California at Santa BarbaraSD01723exoB2/exoB2; chx1-1/CHX1-1 (exoB2; CHX1; exo-; cy-s, ?)
TSCRRID:TSC_SD02600Tetrahymena thermophilaDRH26 HA-5PMID:18708581They are not complete replacement From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.EMA1 (TTHERM_00088150)Macronucleus: C-terminal HA tag of EMA1 with neo3 in 3’flankSD02600mpr1-1/mpr1-1 (ema1[3’neo3,HAc]/?EMA1; pm-r, VII)
TSCRRID:TSC_SD02257Tetrahymena thermophilaBLTGLT4-2BLT germline heterokaryon, heterozygous KO in mic, pm sensitive (120 ug/ml). Cd induced Neo cassette (1.2 ug/ml)--MTT promoter, Neo coding, BTU2 terminator. Construct pBLTMKO, From the Gorovsky lab, University of Rochester.BLT1 (TTHERM_01104960)Micronucleus: Neo3 replaces BLT codingSD02257BLT1/ blt1-1[∆,neo3]; MPR1-?/ MPR1-? (BLT1; mpr1-1; mp-r, ?)
TSCRRID:TSC_SD02397Tetrahymena thermophilaHTA1-D9B6References (2)G4B1G10A x G4B3C1A. mutated HTA1 rescue ∆HTA1∆HTA2 double knockout heterokaryon. Slow growth. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500)Micronucleus: Neo 2 knockout of HTA1 and HTA2 genes Macronucleus: mutated HTA1SD02397hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (hta1[ K5R,K8R,K10R,k12R, K17R]; hta2[∆::neo2]; pm-r, ?)
TSCRRID:TSC_SD01537Tetrahymena thermophilaSB1518PMID:6950403Submitted by Eduardo Orias, University of California, Santa BarbaraSD01537gal1-1/gal1-1; tyr-14/tyr-14 (gal1-1; tyr-14; gal-r; tyr auxotroph, II)
TSCRRID:TSC_SD01631Tetrahymena thermophilaII8G-IA(b)References (3)The Frankel lab could not obtain progeny from crosses using this stock. Its observations are consistent with the reported temperature-sensitive food-vacuoleless phenotype, but not consistent with the reported total loss of oral structures. This stock exhibits multiple unique morphogenetic phenotypes at 37.5o C.: see Frankel (2008: p. 1626, 1632). The Iowa stock is designated II8G-IA to distinguish it from the II8G stock, deposited by L. Rasmussen at the American Type Culture Collection. ATCC. Submitted by Joseph Frankel, University of IowaSD01631presumed phg-/phg- (presumed phg-; phg-, ?)
TSCRRID:TSC_SD02403Tetrahymena thermophilahta1-K123R+htz1 K130R-G2bPMID:19822522HTAX/HTAZ double mutant rescue; Rescue of h∆∆HTA∆HTZ1-F1B1 and B1C5 with Dryl's. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed.HTA1 (TTHERM_00790790), HTA2 (TTHERM_00316500), HTA3 (TTHERM_00143660)Micronucleus: Neo2 knockout of HTAX, HTA1, HTAZ Macronucleus: mutant HTAX and HTAZ rescue of mac KOSD02403htax[∆::neo2]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2]; htaz[∆::neo2]/htaz[∆::neo2] (htax[K123R]/htax[∆::neo2]; hta1[∆::neo2]/hta1[∆::neo2]; htaz[K130R]/htaz[∆;;neo2]; pm-r, ?)
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