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on page 1 showing 20 out of 3,808 results

Cite this (MGI Cat# 4397677, RRID:MGI:4397677)

Source Database: MGI, catalog # 4397677
Genetic Background: FVB.129-Kcnq3
Affected Genes: Kcnq3
Genomic Alteration: tm1.1Naas
Availability: Availability unknown check source stock center
Reference: PMID:18483067
Notes: decreased body size, nervous system phenotype, abnormal hippocampus morphology, astrocytosis, premature death, neonatal lethality, incomplete penetrance, seizures Allele Detail: Targeted

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Cite this (MGI Cat# 5307019, RRID:MGI:5307019)

Source Database: MGI, catalog # 5307019
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Affected Genes: Col3a1
Genomic Alteration: m1Lsmi
Availability: Availability unknown check source stock center
Reference: PMID:21071432
Notes: aortic dissection, premature death, abnormal aorta smooth muscle morphology, abnormal aorta elastic tissue morphology, aortic dissection, premature death, increased systemic arterial systolic blood pressure, increased vasoconstriction, abnormal response/metabolism to endogenous compounds Allele Detail: Spontaneous

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Cite this (MGI Cat# 5007742, RRID:MGI:5007742)

Source Database: MGI, catalog # 5007742
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Affected Genes: Cul9
Genomic Alteration: tm1.2Yxi
Availability: Availability unknown check source stock center
Reference: PMID:21487039
Notes: increased incidence of tumors by chemical induction, decreased body weight, decreased cellular sensitivity to gamma-irradiation, decreased cellular sensitivity to ultraviolet irradiation, increased liver tumor incidence, increased tumor incidence, premature death, increased sarcoma incidence, increased pituitary gland tumor incidence, cellular phenotype, increased lung tumor incidence, increased lymphoma incidence, increased ovary tumor incidence Allele Detail: Targeted

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Cite this (MGI Cat# 3720106, RRID:MGI:3720106)

Source Database: MGI, catalog # 3720106
Genetic Background: involves: FVB
Affected Genes:
Genomic Alteration: Tg(Thy1-App*R609D*K612E)6Vln
Availability: Availability unknown check source stock center
Reference: PMID:8635459
Notes: tonic-clonic seizures, abnormal respiration, decreased susceptibility to pharmacologically induced seizures, increased susceptibility to pharmacologically induced seizures, abnormal response to new environment, increased aggression towards mice, facial muscle spasm, abnormal locomotor activation, behavioral arrest, premature death, myoclonus, lethargy, increased thigmotaxis, clonic seizures, seizures Allele Detail: Transgenic

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Cite this (MGI Cat# 3801484, RRID:MGI:3801484)

Source Database: MGI, catalog # 3801484
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3H/HeSn
Affected Genes: Mecp2
Genomic Alteration: tm1Pplt
Availability: Availability unknown check source stock center
Reference: PMID:16467389
Notes: lethargy, weight loss, postnatal growth retardation, premature death, malocclusion Allele Detail: Targeted

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Cite this (MGI Cat# 2174949, RRID:MGI:2174949)

Source Database: MGI, catalog # 2174949
Genetic Background: involves: 129S5/SvEvBrd
Affected Genes: Ednrb
Genomic Alteration: tm1Ywa
Availability: Availability unknown check source stock center
Reference: PMID:8001159, PMID:10496965
Notes: intestinal obstruction, abnormal choroid pigmentation, abnormal coat/hair pigmentation, decreased acute inflammation, hypoalgesia, premature death, cachexia, abnormal hair follicle melanocyte morphology, postnatal growth retardation, white spotting, variable depigmentation, aganglionic megacolon Allele Detail: Targeted

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Cite this (MGI Cat# 5478500, RRID:MGI:5478500)

Source Database: MGI, catalog # 5478500
Genetic Background: MRL.Cg-Tlr9 Fas
Affected Genes: Fas, Tlr9
Genomic Alteration: tm1Aki; lpr
Availability: Availability unknown check source stock center
Reference: PMID:16973389
Notes: increased double-negative T cell number, premature death, kidney inflammation, increased susceptibility to systemic lupus erythematosus, enlarged spleen, increased IgG level, increased CD4-positive, alpha beta T cell number, abnormal plasmacytoid dendritic cell physiology, abnormal renal glomerulus morphology, increased autoantibody level, decreased autoantibody level, abnormal B cell activation, glomerulonephritis, increased circulating interferon-alpha level, increased IgG3 level, increased IgG2a level, enlarged lymph nodes Allele Detail: Spontaneous, Targeted

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Cite this (MGI Cat# 5510144, RRID:MGI:5510144)

Source Database: MGI, catalog # 5510144
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Affected Genes: Kit
Genomic Alteration: tm5.1Bsm
Availability: Availability unknown check source stock center
Reference: PMID:22652566
Notes: increased tumor growth/size, premature death, increased gastrointestinal tumor incidence, lethality, incomplete penetrance, decreased mean corpuscular volume, interstitial cells of Cajal hyperplasia Allele Detail: Targeted

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Cite this (MGI Cat# 5446806, RRID:MGI:5446806)

Source Database: MGI, catalog # 5446806
Genetic Background: involves: 129 * 129S6/SvEvTac * C57BL/6
Affected Genes: Bcs1l
Genomic Alteration: tm1.1Levp
Availability: Availability unknown check source stock center
Reference: PMID:22829922
Notes: hepatic steatosis, abnormal mitochondrial physiology, hypoactivity, increased liver iron level, hunched posture, liver fibrosis, premature death, slow postnatal weight gain, small liver, weight loss, abnormal liver morphology, abnormal cellular respiration, increased circulating lactate level, abnormal proximal convoluted tubule morphology, decreased body weight, Leydig cell hypoplasia, increased mitochondria size, decreased liver glycogen level Allele Detail: Targeted

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Cite this (MGI Cat# 3590544, RRID:MGI:3590544)

Source Database: MGI, catalog # 3590544
Genetic Background: involves: 129S1/Sv * C57BL/6J
Affected Genes: Cux1
Genomic Alteration: tm1Rhsc
Availability: Availability unknown check source stock center
Reference: PMID:11739170
Notes: decreased body size, decreased double-positive T cell number, cachexia, decreased total body fat amount, abnormal bone structure, abnormal tumor necrosis factor level, small thymus, neonatal lethality, incomplete penetrance, abnormal hair follicle morphology, postnatal growth retardation, decreased B cell number, thymus hypoplasia, thymus cortex hypoplasia, premature death, increased hair follicle number, alopecia, wavy vibrissae, abnormal myelopoiesis, abnormal T cell differentiation, decreased thymocyte number Allele Detail: Targeted

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Cite this (MGI Cat# 3817856, RRID:MGI:3817856)

Source Database: MGI, catalog # 3817856
Genetic Background: C57BL/6J-Foxp3
Affected Genes: Foxp3
Genomic Alteration: m1Btlr
Availability: Availability unknown check source stock center
Reference:
Notes: dry skin, alopecia, skin lesions, scaly skin, azoospermia, abnormal reproductive system development, premature death, decreased body size Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 3851214, RRID:MGI:3851214)

Source Database: MGI, catalog # 3851214
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/NJ
Affected Genes: Scn1a
Genomic Alteration: tm1Wac; Tg(Scn1a*)RH9Aesc
Availability: Availability unknown check source stock center
Reference: PMID:19409490
Notes: premature death Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3613447, RRID:MGI:3613447)

Source Database: MGI, catalog # 3613447
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6J
Affected Genes: Apc, Zbtb33
Genomic Alteration: tm1.1Bird; Min
Availability: Availability unknown check source stock center
Reference: PMID:16354691
Notes: premature death, increased intestinal adenoma incidence, decreased tumor growth/size Allele Detail: Targeted, Chemically induced (ENU)

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Cite this (MGI Cat# 2669401, RRID:MGI:2669401)

Source Database: MGI, catalog # 2669401
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Affected Genes: Cav1
Genomic Alteration: tm1Mls
Availability: Availability unknown check source stock center
Reference: PMID:16982927, PMID:17200204, PMID:17550335, PMID:16982844, PMID:14690422, PMID:17293479, PMID:11689550, PMID:12759258, PMID:11739396, PMID:11457855, PMID:16501011, PMID:12368209
Notes: abnormal compact bone morphology, increased cerebral infarction size, increased susceptibility to bacterial infection, increased circulating interleukin-6 level, increased circulating interferon-gamma level, impaired neutrophil recruitment, abnormal cytokine level, abnormal macrophage physiology, increased susceptibility to bacterial infection induced morbidity/mortality, abnormal chemokine level, increased circulating tumor necrosis factor level, abnormal homeostasis, absent caveolae, abnormal vesicle-mediated transport, absent caveolae, abnormal skeletal muscle fiber morphology, increased circulating triglyceride level, increased brown adipose tissue amount, homeostasis/metabolism phenotype, decreased circulating leptin level, increased food intake, decreased susceptibility to diet-induced obesity, liver/biliary system phenotype, slow postnatal weight gain, decreased body weight, decreased total body fat amount, absent caveolae, abnormal mammary gland morphology, abnormal mammary gland duct morphology, abnormal mammary fat pad morphology, abnormal blood homeostasis, abnormal circulating free fatty acids level, abnormal fat cell morphology, abnormal gonadal fat pad morphology, absent subcutaneous adipose tissue, abnormal lipid homeostasis, decreased white fat cell lipid droplet size, decreased white adipose tissue amount, decreased subcutaneous adipose tissue amount, increased circulating VLDL triglyceride level, impaired exercise endurance, abnormal vasoconstriction, absent caveolae, thick pulmonary interalveolar septum, abnormal vasodilation, abnormal pulmonary alveolar parenchyma morphology, mammary gland duct hyperplasia, abnormal mammary gland epithelium morphology, neoplasm, mammary gland hyperplasia, epidermal hyperplasia, increased incidence of tumors by chemical induction, increased bone trabecula number, increased compact bone area, premature bone ossification, increased trabecular bone thickness, increased bone strength, abnormal osteoclast morphology, abnormal long bone epiphysis morphology, abnormal bone trabecula morphology, abnormal bone mineralization, abnormal long bone metaphysis morphology, abnormal nitric oxide homeostasis, decreased susceptibility to endotoxin shock, abnormal neutrophil physiology, heart left ventricle hypertrophy, abnormal pulmonary endothelial cell surface, abnormal myocardial fiber morphology, cardiac hypertrophy, decreased cardiac muscle contractility, dilated heart right ventricle, abnormal myocardium layer morphology, lung inflammation, premature death, pulmonary hypertension, pulmonary hyperemia, thick pulmonary interalveolar septum, thick ventricular wall, congestive heart failure, cardiac fibrosis, thick interventricular septum Allele Detail: Targeted

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Cite this (MGI Cat# 2174763, RRID:MGI:2174763)

Source Database: MGI, catalog # 2174763
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Affected Genes: Tcirg1
Genomic Alteration: tm1Ypl
Availability: Availability unknown check source stock center
Reference: PMID:25811986, PMID:10581033
Notes: decreased body weight, abnormal bone marrow cavity morphology, rickets, osteopetrosis, osteopetrosis, decreased vitamin D level, decreased circulating calcium level, decreased compact bone thickness, increased bone mineral density, absent compact bone, abnormal long bone metaphysis morphology, abnormal bone mineralization, failure of tooth eruption, absent teeth, short limbs, abnormal long bone hypertrophic chondrocyte zone, premature death, abnormal osteoclast physiology Allele Detail: Targeted

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Cite this (MGI Cat# 4437767, RRID:MGI:4437767)

Source Database: MGI, catalog # 4437767
Genetic Background: involves: C57BL/6J * CBA/J
Affected Genes:
Genomic Alteration: Tg(Pkd1)6Mtru
Availability: Availability unknown check source stock center
Reference: PMID:20053665
Notes: decreased urine creatinine level, decreased urine urea nitrogen level, liver fibrosis, liver cysts, kidney epithelium hyperplasia, kidney cysts, pale kidney, polyuria, thick interventricular septum, premature death, kidney cortex cysts, increased urine osmolality, increased hepatocyte proliferation, increased heart weight, increased circulating sodium level, abnormal renal tubule epithelium morphology, increased cardiac muscle contractility, increased blood osmolality, hematuria, heart left ventricle hypertrophy, glomerulosclerosis, increased urine protein level, renal interstitial fibrosis, increased kidney cell proliferation, dilated renal tubules, thick ventricular wall, dilated heart, decreased hematocrit, cardiac hypertrophy, kidney medulla cysts, nephrocalcinosis, nephrolithiasis, renal cast, abnormal aortic valve cusp morphology Allele Detail: Transgenic

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Cite this (MGI Cat# 3652717, RRID:MGI:3652717)

Source Database: MGI, catalog # 3652717
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6 * SJL
Affected Genes: Xrcc4, Trp53, Tg(Nes-cre)1Kln
Genomic Alteration: tm1Brd; tm2Fwa; Tg(Nes-cre)1Kln; tm2.1Fwa
Availability: Availability unknown check source stock center
Reference: PMID:16670198
Notes: premature death, increased medulloblastoma incidence, enlarged cranium, abnormal cerebellum vermis morphology, abnormal cerebellar granule layer morphology Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 5432346, RRID:MGI:5432346)

Source Database: MGI, catalog # 5432346
Genetic Background: involves: C57BL/6 * SJL
Affected Genes:
Genomic Alteration: Tg(Ela1-Myc)160Bri
Availability: Availability unknown check source stock center
Reference: PMID:1986386
Notes: jaundice, increased metastatic potential, exocrine pancreas atrophy, premature death, small pancreas, increased pancreas tumor incidence, increased pancreatic acinar cell carcinoma incidence Allele Detail: Transgenic

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Cite this (MGI Cat# 5000009, RRID:MGI:5000009)

Source Database: MGI, catalog # 5000009
Genetic Background: involves: 129S4/SvJae * C57BL/6 * NMRI
Affected Genes: Col1a1, Gt(ROSA)26Sor
Genomic Alteration: tm1(rtTA*M2)Jae; Tg(CMV-rtTA)4Bjd; tm10(tetO*-RFP/RNAi:Rpa3)Slowe
Availability: Availability unknown check source stock center
Reference: PMID:21482754
Notes: premature death, weight loss Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3640190, RRID:MGI:3640190)

Source Database: MGI, catalog # 3640190
Genetic Background: C3.Cg-Reln
Affected Genes: Reln
Genomic Alteration: rl
Availability: Availability unknown check source stock center
Reference: PMID:7127145, PMID:4644329
Notes: abnormal stratification in cerebral cortex, abnormal dentate gyrus morphology, abnormal cerebral cortex morphology, abnormal hippocampus morphology, abnormal olfactory cortex morphology, abnormal entorhinal cortex morphology, abnormal neuronal migration, abnormal sensory neuron innervation pattern, slow postnatal weight gain, ataxia, behavior/neurological phenotype, postnatal growth retardation, abnormal hippocampus CA1 region morphology, diarrhea, premature death, abnormal hippocampus CA2 region morphology Allele Detail: Spontaneous

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