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on page 1 showing 20 out of 3,761 results

Cite this (MGI Cat# 5437688, RRID:MGI:5437688)

Source Database: MGI, catalog # 5437688
Genetic Background: involves: C57BL/6 * DBA/2
Affected Genes:
Genomic Alteration: Tg(SERPINC1-SV40)A1Pbr
Availability: Availability unknown check source stock center
Reference: PMID:1660504
Notes: abnormal liver morphology, increased metastatic potential, anisocytosis, abnormal hepatocyte physiology, premature death, increased hepatocellular carcinoma incidence, abnormal cell nucleus morphology Allele Detail: Transgenic

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Cite this (MGI Cat# 5314090, RRID:MGI:5314090)

Source Database: MGI, catalog # 5314090
Genetic Background: involves: 129P2/OlaHsd * 129S2/SvPas * BALB/cJ
Affected Genes: Cd19, Gt(ROSA)26Sor, Tcrb, Tcrd
Genomic Alteration: tm1Mom; tm10(Lmp1)Rsky; tm1(cre)Cgn
Availability: Availability unknown check source stock center
Reference: PMID:22341446
Notes: enlarged spleen, increased B cell number, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 3768518, RRID:MGI:3768518)

Source Database: MGI, catalog # 3768518
Genetic Background: involves: C3H * C57BL/6
Affected Genes: Tg(Prnp-MAPT*P301S)PS19Vle
Genomic Alteration: Tg(Prnp-MAPT*P301S)PS19Vle
Availability: Availability unknown check source stock center
Reference: PMID:17270732, PMID:21698260, PMID:26931567, PMID:20802182
Notes: reduced long term potentiation, hippocampus atrophy, astrocytosis, decreased paired-pulse facilitation, tau protein deposits, neurofibrillary tangles, abnormal entorhinal cortex morphology, abnormal amygdala morphology, abnormal dentate gyrus morphology, abnormal hippocampal mossy fiber morphology, abnormal spinal cord white matter morphology, weakness, tau protein deposits, weight loss, hunched posture, neurofibrillary tangles, paralysis, paresis, premature death, paralysis, neurodegeneration, decreased hippocampus volume, loss of hippocampal neurons, limb grasping, hunched posture, hippocampal neuron degeneration, dystrophic muscle, abnormal excitatory postsynaptic potential, abnormal hippocampus pyramidal cell morphology, tau protein deposits, premature death, abnormal CNS synaptic transmission, brain atrophy, dilated brain ventricles, abnormal cerebral cortex morphology, abnormal spatial learning, progressive muscle weakness Allele Detail: Transgenic

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Cite this (MGI Cat# 4429672, RRID:MGI:4429672)

Source Database: MGI, catalog # 4429672
Genetic Background: C3.Cg-a Zfp24/GrsrJ
Affected Genes: Zfp24
Genomic Alteration: hmcns
Availability: Availability unknown check source stock center
Reference: PMID:20080941
Notes: premature death, abnormal myelin sheath morphology, decreased spinal cord size, decreased brain size, abnormal spinal cord white matter morphology, tremors, decreased oligodendrocyte number, tonic seizures Allele Detail: Spontaneous

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Cite this (MGI Cat# 5444174, RRID:MGI:5444174)

Source Database: MGI, catalog # 5444174
Genetic Background: involves: C57BL/6NTac
Affected Genes: Pi4ka, Gt(ROSA)26Sor
Genomic Alteration: tm9(cre/ESR1)Arte; tm1.1Arte
Availability: Availability unknown check source stock center
Reference: PMID:22896614
Notes: abnormal intestine morphology, abnormal cecum morphology, abnormal digestive system morphology, abnormal duodenum morphology, distended stomach, premature death, abnormal gastric parietal cell morphology, abnormal stomach mucosa morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5285700, RRID:MGI:5285700)

Source Database: MGI, catalog # 5285700
Genetic Background: B6.129-Trp53 Espl1
Affected Genes: Espl1, Trp53
Genomic Alteration: Gt(XL058)Byg; tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:21799785
Notes: abnormal bone marrow cell physiology, premature death, abnormal splenocyte morphology, aneuploidy, increased splenocyte proliferation, altered tumor pathology, increased carcinoma incidence, increased lymphoma incidence, increased metastatic potential Allele Detail: Targeted, Gene trapped

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Cite this (MGI Cat# 5445344, RRID:MGI:5445344)

Source Database: MGI, catalog # 5445344
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J
Affected Genes: Flt3, Kmt2a
Genomic Alteration: tm1Clgr; tm1Dgg
Availability: Availability unknown check source stock center
Reference: PMID:22674806
Notes: thrombocytopenia, increased leukemia incidence, premature death, increased leukocyte cell number, increased erythroblast number, enlarged spleen, anemia Allele Detail: Targeted

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Cite this (MGI Cat# 3716846, RRID:MGI:3716846)

Source Database: MGI, catalog # 3716846
Genetic Background: involves: C57BL/6 * KOR
Affected Genes: Apoe
Genomic Alteration: shl
Availability: Availability unknown check source stock center
Reference: PMID:10087291
Notes: atherosclerotic lesions, alopecia, premature death, increased circulating cholesterol level, xanthoma Allele Detail: Spontaneous

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Cite this (MGI Cat# 4947965, RRID:MGI:4947965)

Source Database: MGI, catalog # 4947965
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
Affected Genes: Csrp3
Genomic Alteration: tm1.1Rkn
Availability: Availability unknown check source stock center
Reference: PMID:20044516
Notes: abnormal heart septum morphology, premature death, abnormal heart morphology, cardiomyopathy, increased cardiac muscle contractility Allele Detail: Targeted

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Cite this (MGI Cat# 5432345, RRID:MGI:5432345)

Source Database: MGI, catalog # 5432345
Genetic Background: involves: C57BL/6 * SJL
Affected Genes:
Genomic Alteration: Tg(Ela1-Myc)159Bri
Availability: Availability unknown check source stock center
Reference: PMID:1986386
Notes: increased metastatic potential, small pancreas, premature death, increased pancreatic acinar cell carcinoma incidence, jaundice, increased pancreas tumor incidence, exocrine pancreas atrophy Allele Detail: Transgenic

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Cite this (MGI Cat# 5501521, RRID:MGI:5501521)

Source Database: MGI, catalog # 5501521
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Affected Genes: Vdr
Genomic Alteration: tm1.1Pcn
Availability: Availability unknown check source stock center
Reference: PMID:23389957
Notes: decreased circulating phosphate level, abnormal bone ossification, abnormal vitamin D level, alopecia, decreased circulating calcium level, disorganized long bone epiphyseal plate, increased activity of parathyroid, weight loss, premature death, increased osteoid volume, postnatal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 3626205, RRID:MGI:3626205)

Source Database: MGI, catalog # 3626205
Genetic Background: involves: 129S4/SvJae
Affected Genes: Nhlh1
Genomic Alteration: tm1Irk
Availability: Availability unknown check source stock center
Reference: PMID:12077327
Notes: decreased heart rate variability, irregular heartbeat, premature death, ventricular premature beat, abnormal QT variability, abnormal parasympathetic nervous system physiology Allele Detail: Targeted

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Cite this (MGI Cat# 3653638, RRID:MGI:3653638)

Source Database: MGI, catalog # 3653638
Genetic Background: involves: C3H/HeJ * C57BL/6J
Affected Genes: Kl
Genomic Alteration: kl
Availability: Availability unknown check source stock center
Reference: PMID:12475907, PMID:11016890, PMID:12446599
Notes: postnatal growth retardation, decreased osteoclast cell number, decreased B cell number, decreased body weight, osteopetrosis, oxidative stress, premature death, abnormal nervous system physiology, abnormal long term object recognition memory, abnormal cued conditioning behavior, abnormal contextual conditioning behavior, increased insulin sensitivity, decreased circulating insulin level, decreased insulin secretion, hypoglycemia, short femur Allele Detail: Transgenic

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Cite this (MGI Cat# 3706822, RRID:MGI:3706822)

Source Database: MGI, catalog # 3706822
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
Affected Genes: Foxo1, Foxo3, Tg(Mx1-cre)1Cgn, Foxo4
Genomic Alteration: tm1Rdp; Tg(Mx1-cre)1Cgn
Availability: Availability unknown check source stock center
Reference: PMID:17254969
Notes: increased hemangiosarcoma incidence, premature death, increased hemangioma incidence, increased T cell derived lymphoma incidence, increased hamartoma incidence Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 5052381, RRID:MGI:5052381)

Source Database: MGI, catalog # 5052381
Genetic Background: involves: C57BL/6 * DBA/2
Affected Genes:
Genomic Alteration: Tg(HTT*/EGFP)150Nn
Availability: Availability unknown check source stock center
Reference: PMID:15836623
Notes: abnormal nervous system morphology, premature death, abnormal cerebral cortex morphology, abnormal hippocampus morphology, abnormal involuntary movement, abnormal striatum morphology, ataxia, tremors, neuronal intranuclear inclusions, limb grasping Allele Detail: Transgenic

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Cite this (MGI Cat# 4819582, RRID:MGI:4819582)

Source Database: MGI, catalog # 4819582
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
Affected Genes: Gt(ROSA)26Sor, Lin9
Genomic Alteration: tm1.1Sgau; tm1(cre/ERT)Brn
Availability: Availability unknown check source stock center
Reference: PMID:20404087
Notes: premature death, abnormal cell nucleus morphology, abnormal small intestinal crypt cell proliferation, abnormal small intestinal villus morphology, abnormal small intestine morphology, decreased fibroblast proliferation, abnormal mitosis Allele Detail: Targeted

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Cite this (MGI Cat# 2181781, RRID:MGI:2181781)

Source Database: MGI, catalog # 2181781
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Affected Genes: Ank3
Genomic Alteration: tm1Bnt
Availability: Availability unknown check source stock center
Reference: PMID:9832557
Notes: decreased Purkinje cell number, small cerebellum, tremors, hypoactivity, convulsive seizures, ataxia, abnormal gait, Purkinje cell degeneration, thin cerebellar molecular layer, impaired ability to fire action potentials, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 3809773, RRID:MGI:3809773)

Source Database: MGI, catalog # 3809773
Genetic Background: involves: 129 * C57BL/6 * CD-1
Affected Genes: Tg(Camk2a-tTA)1Mmay, Psmc1
Genomic Alteration: tm1Maye; Tg(Camk2a-tTA)1Mmay; Tg(tetO-cre)1Lin
Availability: Availability unknown check source stock center
Reference: PMID:18701681
Notes: alpha-synuclein inclusion body, neurodegeneration, increased neuron apoptosis, abnormal fear/anxiety-related behavior, abnormal spatial learning, thin cerebral cortex, enlarged brain ventricles, loss of cortex neurons, forebrain atrophy, postnatal growth retardation, premature death, abnormal eating behavior, gliosis Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3846426, RRID:MGI:3846426)

Source Database: MGI, catalog # 3846426
Genetic Background: B6.129S7-Cisd2
Affected Genes: Cisd2
Genomic Alteration: tm1Tfts
Availability: Availability unknown check source stock center
Reference: PMID:19451219
Notes: decreased total body fat amount, retinal neovascularization, thick epidermis, decreased insulin secretion, decreased trabecular bone thickness, decreased oxygen consumption, oliguria, decreased tidal volume, decreased hair follicle number, decreased food intake, decreased body mass index, decreased body size, decreased body weight, decreased subcutaneous adipose tissue amount, abnormal optic nerve morphology, premature death, demyelination, abnormal respiratory function, abnormal muscle fiber morphology, abnormal mitochondrion morphology, abnormal glucose homeostasis, abnormal defecation, abnormal coat/hair pigmentation, small thoracic cavity, abnormal myocardium layer morphology, decreased bone mineral density, premature aging, decreased fluid intake, corneal opacity, blindness, axon degeneration, impaired glucose tolerance, increased insulin sensitivity, kyphosis, lordosis, muscle degeneration, exophthalmos, prominent ears, abnormal respiratory electron transport chain, neurodegeneration, postnatal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 5790646, RRID:MGI:5790646)

Source Database: MGI, catalog # 5790646
Genetic Background: involves: BALB/cAnNHsd * C3H/HeNHsd
Affected Genes: Gnptab
Genomic Alteration: nym
Availability: Availability unknown check source stock center
Reference: PMID:25107912
Notes: abnormal pancreas morphology, brain atrophy, cerebellum atrophy, decreased brain size, progressive muscle weakness, Purkinje cell axonal dystrophy, abnormal cerebellum white matter morphology, thick skin, premature death, lysosomal protein accumulation, brain inflammation, astrocytosis, abnormal spine curvature, abnormal cognition, Purkinje cell degeneration, prenatal lethality, incomplete penetrance, penis prolapse, limb grasping, impaired coordination, small nasal bridge, decreased body size, decreased survivor rate, flattened snout, kyphosis, postnatal growth retardation, thick eyelids, abnormal cerebellar cortex morphology, abnormal cerebellar molecular layer, abnormal chondrocyte morphology, abnormal enzyme/coenzyme activity, abnormal hippocampus CA1 region morphology, abnormal hippocampus CA3 region morphology, abnormal fertility/fecundity, abnormal skin turgor, demyelination, axonal spheroids, abnormal pancreatic acinar cell morphology, abnormal skeleton morphology, abnormal facial morphology, abnormal gait, ataxia Allele Detail: Chemically induced (ENU)

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