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on page 1 showing 20 out of 3,715 results from 1 sources

Cite this (MGI Cat# 5523996, RRID:MGI:5523996)

Source Database: MGI, catalog # 5523996
Genetic Background: (C57BL/6J x 129S6/SvEvTac-Scn1a)F1
Affected Genes: Scn1a
Genomic Alteration: tm1Kea
Availability: Availability unknown check source stock center
Reference: PMID:24152123
Notes: premature death, seizures Allele Detail: Targeted

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Cite this (MGI Cat# 5437688, RRID:MGI:5437688)

Source Database: MGI, catalog # 5437688
Genetic Background: involves: C57BL/6 * DBA/2
Affected Genes:
Genomic Alteration: Tg(SERPINC1-SV40)A1Pbr
Availability: Availability unknown check source stock center
Reference: PMID:1660504
Notes: abnormal cell nucleus morphology, abnormal hepatocyte physiology, anisocytosis, increased hepatocellular carcinoma incidence, increased metastatic potential, premature death, abnormal liver morphology Allele Detail: Transgenic

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Cite this (MGI Cat# 3768518, RRID:MGI:3768518)

Source Database: MGI, catalog # 3768518
Genetic Background: involves: C3H * C57BL/6
Affected Genes:
Genomic Alteration: Tg(Prnp-MAPT*P301S)PS19Vle
Availability: Availability unknown check source stock center
Reference: PMID:17270732, PMID:20802182, PMID:26931567, PMID:21698260
Notes: abnormal CNS synaptic transmission, brain atrophy, dilated brain ventricles, abnormal cerebral cortex morphology, abnormal dentate gyrus morphology, abnormal excitatory postsynaptic potential, hippocampus atrophy, astrocytosis, decreased paired-pulse facilitation, abnormal hippocampus pyramidal cell morphology, dystrophic muscle, hippocampal neuron degeneration, hunched posture, hunched posture, limb grasping, loss of hippocampal neurons, neurodegeneration, neurofibrillary tangles, neurofibrillary tangles, paralysis, premature death, premature death, progressive muscle weakness, reduced long term potentiation, tau protein deposits, tau protein deposits, tau protein deposits, weakness, abnormal spinal cord white matter morphology, abnormal hippocampal mossy fiber morphology, abnormal amygdala morphology, abnormal entorhinal cortex morphology, decreased hippocampus volume, paralysis, paresis, weight loss, abnormal spatial learning Allele Detail: Transgenic

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Cite this (MGI Cat# 4429672, RRID:MGI:4429672)

Source Database: MGI, catalog # 4429672
Genetic Background: C3.Cg-a Zfp24/GrsrJ
Affected Genes: Zfp24
Genomic Alteration: hmcns
Availability: Availability unknown check source stock center
Reference: PMID:20080941
Notes: abnormal myelin sheath morphology, abnormal spinal cord white matter morphology, decreased brain size, decreased spinal cord size, premature death, decreased oligodendrocyte number, tonic seizures, tremors Allele Detail: Spontaneous

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Cite this (MGI Cat# 5444174, RRID:MGI:5444174)

Source Database: MGI, catalog # 5444174
Genetic Background: involves: C57BL/6NTac
Affected Genes: Gt(ROSA)26Sor, Pi4ka
Genomic Alteration: tm9(cre/ESR1)Arte; tm1.1Arte
Availability: Availability unknown check source stock center
Reference: PMID:22896614
Notes: abnormal cecum morphology, abnormal digestive system morphology, abnormal duodenum morphology, abnormal gastric parietal cell morphology, abnormal intestine morphology, abnormal stomach mucosa morphology, distended stomach, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 3716846, RRID:MGI:3716846)

Source Database: MGI, catalog # 3716846
Genetic Background: involves: C57BL/6 * KOR
Affected Genes: Apoe
Genomic Alteration: shl
Availability: Availability unknown check source stock center
Reference: PMID:10087291
Notes: alopecia, increased circulating cholesterol level, premature death, xanthoma, atherosclerotic lesions Allele Detail: Spontaneous

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Cite this (MGI Cat# 5285700, RRID:MGI:5285700)

Source Database: MGI, catalog # 5285700
Genetic Background: B6.129-Trp53 Espl1
Affected Genes: Espl1, Trp53
Genomic Alteration: Gt(XL058)Byg; tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:21799785
Notes: altered tumor pathology, increased carcinoma incidence, increased lymphoma incidence, increased metastatic potential, premature death, abnormal bone marrow cell physiology, abnormal splenocyte morphology, aneuploidy, increased splenocyte proliferation Allele Detail: Targeted, Gene trapped

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Cite this (MGI Cat# 5445344, RRID:MGI:5445344)

Source Database: MGI, catalog # 5445344
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6J
Affected Genes: Flt3, Kmt2a
Genomic Alteration: tm1Clgr; tm1Dgg
Availability: Availability unknown check source stock center
Reference: PMID:22674806
Notes: anemia, thrombocytopenia, enlarged spleen, increased erythroblast number, increased leukocyte cell number, increased leukemia incidence, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 4947965, RRID:MGI:4947965)

Source Database: MGI, catalog # 4947965
Genetic Background: either: (involves: Black Swiss) or (involves: C57BL/6N)
Affected Genes: Csrp3
Genomic Alteration: tm1.1Rkn
Availability: Availability unknown check source stock center
Reference: PMID:20044516
Notes: abnormal heart morphology, abnormal heart septum morphology, cardiomyopathy, increased cardiac muscle contractility, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 5432345, RRID:MGI:5432345)

Source Database: MGI, catalog # 5432345
Genetic Background: involves: C57BL/6 * SJL
Affected Genes:
Genomic Alteration: Tg(Ela1-Myc)159Bri
Availability: Availability unknown check source stock center
Reference: PMID:1986386
Notes: exocrine pancreas atrophy, increased metastatic potential, increased pancreas tumor incidence, increased pancreatic acinar cell carcinoma incidence, jaundice, premature death, small pancreas Allele Detail: Transgenic

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Cite this (MGI Cat# 5501521, RRID:MGI:5501521)

Source Database: MGI, catalog # 5501521
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Affected Genes: Vdr
Genomic Alteration: tm1.1Pcn
Availability: Availability unknown check source stock center
Reference: PMID:23389957
Notes: abnormal bone ossification, abnormal vitamin D level, alopecia, decreased circulating calcium level, decreased circulating phosphate level, disorganized long bone epiphyseal plate, increased activity of parathyroid, increased osteoid volume, postnatal growth retardation, premature death, weight loss Allele Detail: Targeted

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Cite this (MGI Cat# 3626205, RRID:MGI:3626205)

Source Database: MGI, catalog # 3626205
Genetic Background: involves: 129S4/SvJae
Affected Genes: Nhlh1
Genomic Alteration: tm1Irk
Availability: Availability unknown check source stock center
Reference: PMID:12077327
Notes: abnormal QT variability, abnormal parasympathetic nervous system physiology, decreased heart rate variability, irregular heartbeat, premature death, ventricular premature beat Allele Detail: Targeted

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Cite this (MGI Cat# 3653638, RRID:MGI:3653638)

Source Database: MGI, catalog # 3653638
Genetic Background: involves: C3H/HeJ * C57BL/6J
Affected Genes: Kl
Genomic Alteration: kl
Availability: Availability unknown check source stock center
Reference: PMID:12475907, PMID:11016890, PMID:12446599
Notes: abnormal contextual conditioning behavior, abnormal cued conditioning behavior, abnormal long term object recognition memory, abnormal nervous system physiology, oxidative stress, postnatal growth retardation, premature death, decreased osteoclast cell number, decreased B cell number, decreased body weight, osteopetrosis, short femur, hypoglycemia, decreased insulin secretion, increased insulin sensitivity, decreased circulating insulin level Allele Detail: Transgenic

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Cite this (MGI Cat# 3706822, RRID:MGI:3706822)

Source Database: MGI, catalog # 3706822
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
Affected Genes: Foxo1, Foxo3, Tg(Mx1-cre)1Cgn, Foxo4
Genomic Alteration: Tg(Mx1-cre)1Cgn; tm1Rdp
Availability: Availability unknown check source stock center
Reference: PMID:17254969
Notes: increased hemangioma incidence, increased hemangiosarcoma incidence, increased hamartoma incidence, premature death, increased T cell derived lymphoma incidence Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 5052381, RRID:MGI:5052381)

Source Database: MGI, catalog # 5052381
Genetic Background: involves: C57BL/6 * DBA/2
Affected Genes:
Genomic Alteration: Tg(HTT*/EGFP)150Nn
Availability: Availability unknown check source stock center
Reference: PMID:15836623
Notes: abnormal involuntary movement, abnormal nervous system morphology, ataxia, limb grasping, premature death, abnormal cerebral cortex morphology, abnormal hippocampus morphology, abnormal striatum morphology, neuronal intranuclear inclusions, tremors Allele Detail: Transgenic

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Cite this (MGI Cat# 4819582, RRID:MGI:4819582)

Source Database: MGI, catalog # 4819582
Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * SJL
Affected Genes: Gt(ROSA)26Sor, Lin9
Genomic Alteration: tm1.1Sgau; tm1(cre/ERT)Brn
Availability: Availability unknown check source stock center
Reference: PMID:20404087
Notes: abnormal mitosis, abnormal cell nucleus morphology, abnormal small intestinal crypt cell proliferation, abnormal small intestinal villus morphology, abnormal small intestine morphology, decreased fibroblast proliferation, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 2181781, RRID:MGI:2181781)

Source Database: MGI, catalog # 2181781
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Affected Genes: Ank3
Genomic Alteration: tm1Bnt
Availability: Availability unknown check source stock center
Reference: PMID:9832557
Notes: Purkinje cell degeneration, abnormal gait, ataxia, convulsive seizures, decreased Purkinje cell number, hypoactivity, impaired ability to fire action potentials, premature death, small cerebellum, thin cerebellar molecular layer, tremors Allele Detail: Targeted

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Cite this (MGI Cat# 3809773, RRID:MGI:3809773)

Source Database: MGI, catalog # 3809773
Genetic Background: involves: 129 * C57BL/6 * CD-1
Affected Genes: Psmc1
Genomic Alteration: Tg(Camk2a-tTA)1Mmay; tm1Maye; Tg(tetO-cre)1Lin
Availability: Availability unknown check source stock center
Reference: PMID:18701681
Notes: postnatal growth retardation, premature death, abnormal eating behavior, abnormal fear/anxiety-related behavior, abnormal spatial learning, thin cerebral cortex, enlarged brain ventricles, loss of cortex neurons, increased neuron apoptosis, neurodegeneration, gliosis, alpha-synuclein inclusion body, forebrain atrophy Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3846426, RRID:MGI:3846426)

Source Database: MGI, catalog # 3846426
Genetic Background: B6.129S7-Cisd2
Affected Genes: Cisd2
Genomic Alteration: tm1Tfts
Availability: Availability unknown check source stock center
Reference: PMID:19451219
Notes: abnormal myocardium layer morphology, small thoracic cavity, abnormal coat/hair pigmentation, abnormal defecation, prominent ears, exophthalmos, abnormal glucose homeostasis, abnormal mitochondrion morphology, abnormal muscle fiber morphology, abnormal respiratory function, axon degeneration, blindness, corneal opacity, decreased total body fat amount, decreased body mass index, decreased body size, decreased body weight, decreased bone mineral density, decreased trabecular bone thickness, decreased fluid intake, decreased food intake, decreased hair follicle number, decreased insulin secretion, abnormal respiratory electron transport chain, decreased oxygen consumption, decreased subcutaneous adipose tissue amount, decreased tidal volume, oliguria, demyelination, impaired glucose tolerance, increased insulin sensitivity, kyphosis, lordosis, muscle degeneration, neurodegeneration, postnatal growth retardation, premature aging, premature death, retinal neovascularization, thick epidermis, abnormal optic nerve morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5790646, RRID:MGI:5790646)

Source Database: MGI, catalog # 5790646
Genetic Background: involves: BALB/cAnNHsd * C3H/HeNHsd
Affected Genes: Gnptab
Genomic Alteration: nym
Availability: Availability unknown check source stock center
Reference: PMID:25107912
Notes: abnormal facial morphology, abnormal skeleton morphology, abnormal spine curvature, decreased body size, decreased survivor rate, flattened snout, kyphosis, postnatal growth retardation, premature death, thick eyelids, abnormal cerebellar cortex morphology, abnormal cerebellar molecular layer, abnormal chondrocyte morphology, abnormal enzyme/coenzyme activity, abnormal hippocampus CA1 region morphology, abnormal hippocampus CA3 region morphology, abnormal pancreas morphology, abnormal pancreatic acinar cell morphology, brain inflammation, lysosomal protein accumulation, thick skin, abnormal fertility/fecundity, abnormal gait, impaired coordination, limb grasping, penis prolapse, prenatal lethality, incomplete penetrance, Purkinje cell degeneration, abnormal cognition, ataxia, brain atrophy, cerebellum atrophy, decreased brain size, progressive muscle weakness, Purkinje cell axonal dystrophy, abnormal cerebellum white matter morphology, astrocytosis, axonal spheroids, demyelination, abnormal skin turgor, small nasal bridge Allele Detail: Chemically induced (ENU)

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