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on page 1 showing 20 out of 3,744 results from 1 sources

Cite this (MGI Cat# 5796166, RRID:MGI:5796166)

Source Database: MGI, catalog # 5796166
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * FVB/N
Affected Genes: Rb1, Prkar1a, Tg(Col1a1-cre)1Kry, Trp53
Genomic Alteration: tm2Brn; Tg(Col1a1-cre)1Kry; tm1.2Lsk; tm1Brn
Availability: Availability unknown check source stock center
Reference: PMID:26659571
Notes: increased cell migration, premature death, increased osteosarcoma incidence Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3845660, RRID:MGI:3845660)

Source Database: MGI, catalog # 3845660
Genetic Background: involves: 129P2/OlaHsd
Affected Genes: Otx1
Genomic Alteration: tm1Asim
Availability: Availability unknown check source stock center
Reference: PMID:9477321, PMID:10068635
Notes: absent lateral semicircular canal, seizures, decreased brain weight, abnormal telencephalon development, abnormal inner ear morphology, absent ciliary process, abnormal cerebral cortex morphology, absent Harderian gland, absent lacrimal glands, premature death, decreased brain size Allele Detail: Targeted

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Cite this (MGI Cat# 6094247, RRID:MGI:6094247)

Source Database: MGI, catalog # 6094247
Genetic Background: BXSB.129P2(B6)-H2-K1 H2-D1/Dcr
Affected Genes: H2-D1, Yaa, H2-K1
Genomic Alteration: tm1Bpe; Yaa
Availability: Availability unknown check source stock center
Reference: PMID:21964024
Notes: increased susceptibility to systemic lupus erythematosus, premature death Allele Detail: Spontaneous, Targeted

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Cite this (MGI Cat# 3848459, RRID:MGI:3848459)

Source Database: MGI, catalog # 3848459
Genetic Background: involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6
Affected Genes: Dnmt1, Mlh1
Genomic Alteration: tm1Lisk; tm1Jae
Availability: Availability unknown check source stock center
Reference: PMID:11940649
Notes: premature death, increased intestinal adenocarcinoma incidence, increased intestinal adenoma incidence, increased lymphoma incidence Allele Detail: Targeted

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Cite this (MGI Cat# 3758489, RRID:MGI:3758489)

Source Database: MGI, catalog # 3758489
Genetic Background: Not Specified
Affected Genes: Ophn1
Genomic Alteration: tm1Bill
Availability: Availability unknown check source stock center
Reference: PMID:17728457
Notes: abnormal behavior, abnormal response to novelty, abnormal dendrite morphology, dilated third ventricle, abnormal spatial learning, thin cerebral cortex, hydroencephaly, hyperactivity, decreased anxiety-related response, dilated lateral ventricles, abnormal excitatory postsynaptic potential, increased thigmotaxis, premature death, increased exploration in new environment, abnormal aggression-related behavior, decreased aggression towards mice, increased brain size Allele Detail: Targeted

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Cite this (MGI Cat# 5706585, RRID:MGI:5706585)

Source Database: MGI, catalog # 5706585
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
Affected Genes: Clcn3
Genomic Alteration: Tg(tetO-cre)3Jig; Tg(Myh6-tTA)6Smbf; tm1.1Jrhm
Availability: Availability unknown check source stock center
Reference: PMID:19615374
Notes: dilated cardiomyopathy, congestive heart failure, enlarged heart, abnormal heart echocardiography feature, decreased ventricle muscle contractility, abnormal myocardial fiber physiology, increased heart weight, myocardial hypertrophy, premature death Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3714968, RRID:MGI:3714968)

Source Database: MGI, catalog # 3714968
Genetic Background: involves: 129 * BALB/c * C57BL/6
Affected Genes: Spi1
Genomic Alteration: tm1.3Dgt
Availability: Availability unknown check source stock center
Reference: PMID:15146183
Notes: abnormal proerythroblast morphology, spleen hyperplasia, premature death, abnormal liver morphology, abnormal definitive hematopoiesis, decreased B cell number, abnormal spleen morphology, enlarged spleen, increased T cell derived lymphoma incidence, increased liver weight, increased neutrophil cell number, liver hyperplasia, increased spleen weight, increased leukemia incidence, abnormal chromosome number Allele Detail: Targeted

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Cite this (MGI Cat# 5582314, RRID:MGI:5582314)

Source Database: MGI, catalog # 5582314
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CBA
Affected Genes: Tg(Mx1-cre)1Cgn, Kras
Genomic Alteration: tm4Tyj; Tg(Mx1-cre)1Cgn
Availability: Availability unknown check source stock center
Reference: PMID:16720837, PMID:14699048
Notes: myeloid hyperplasia, enlarged spleen, increased monocyte cell number, increased splenocyte proliferation, abnormal erythropoiesis, anisopoikilocytosis, decreased mean corpuscular hemoglobin, increased circulating erythropoietin level, polychromatophilia, reticulocytosis, enlarged spleen, anemia, anemia, abnormal myelopoiesis, abnormal erythropoiesis, enlarged liver, increased leukocyte cell number, premature death Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3810319, RRID:MGI:3810319)

Source Database: MGI, catalog # 3810319
Genetic Background: involves: 129X1/SvJ
Affected Genes: Gt(ROSA)26Sor, Tlx3
Genomic Alteration: tm1(cre)Qima; tm1(Smo/EYFP)Amc
Availability: Availability unknown check source stock center
Reference: PMID:18691547
Notes: premature death, increased medulloblastoma incidence Allele Detail: Targeted

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Cite this (MGI Cat# 3814412, RRID:MGI:3814412)

Source Database: MGI, catalog # 3814412
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Affected Genes: Trp53
Genomic Alteration: tm1Glo
Availability: Availability unknown check source stock center
Reference: PMID:10760284
Notes: increased metastatic potential, increased carcinoma incidence, increased lymphoma incidence, premature death, increased tumor incidence, increased sarcoma incidence, increased fibrosarcoma incidence, increased squamous cell carcinoma incidence, increased hemangiosarcoma incidence, increased osteosarcoma incidence Allele Detail: Targeted

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Cite this (MGI Cat# 3624014, RRID:MGI:3624014)

Source Database: MGI, catalog # 3624014
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv
Affected Genes: Ednrb
Genomic Alteration: tm2(rtTA)Tilg; tm3(tetO)Tilg
Availability: Availability unknown check source stock center
Reference: PMID:10591209
Notes: megacolon, pigmentation phenotype, abnormal enteric neuron morphology, premature death, absent coat pigmentation, digestive/alimentary phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 4462851, RRID:MGI:4462851)

Source Database: MGI, catalog # 4462851
Genetic Background: involves: 129S/SvEv * 129S2/SvPas * BALB/c * C57BL/6
Affected Genes: Ssbp2, Trp53
Genomic Alteration: tm1Lana; tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:20348955
Notes: premature death, increased T cell derived lymphoma incidence, thymus hypoplasia Allele Detail: Targeted

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Cite this (MGI Cat# 5634093, RRID:MGI:5634093)

Source Database: MGI, catalog # 5634093
Genetic Background: involves: C57BL/6 * DBA/2
Affected Genes:
Genomic Alteration: Tg(Mbp-SNCA)29Ema
Availability: Availability unknown check source stock center
Reference: PMID:16291942
Notes: loss of basal ganglia neurons, premature death, abnormal axon morphology, seizures, abnormal dendrite morphology, abnormal mitochondrion morphology, abnormal motor coordination/balance, abnormal mitochondrial crista morphology, tremors, abnormal corpus callosum morphology, abnormal neocortex morphology, demyelination, impaired coordination, abnormal mitochondrial shape, abnormal neurite morphology, abnormal sexual interaction, ataxia, astrocytosis, increased mitochondria size, alpha-synuclein inclusion body, neurodegeneration Allele Detail: Transgenic

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Cite this (MGI Cat# 5007701, RRID:MGI:5007701)

Source Database: MGI, catalog # 5007701
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Affected Genes: Tg(Mx1-cre)1Cgn, Gt(ROSA)26Sor, Npm1
Genomic Alteration: TgTn(pb-sb-GrOnc)#aGsva; tm1Gsva; tm4(CAG-hsb5)Nki; Tg(Mx1-cre)1Cgn
Availability: Availability unknown check source stock center
Reference: PMID:21441929
Notes: increased acute promyelocytic leukemia incidence, increased B cell derived lymphoma incidence, increased hemangiosarcoma incidence, increased lymphoma incidence, increased leukemia incidence, premature death Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 5559229, RRID:MGI:5559229)

Source Database: MGI, catalog # 5559229
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * SJL
Affected Genes: Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas
Genomic Alteration: Tg(APPSwFlLon,PSEN1*M146L*L286V)6799Vas; Tg(Thy1-MAPT*)30Schd
Availability: Availability unknown check source stock center
Reference: PMID:24076100
Notes: decreased brain weight, neurofibrillary tangles, impaired coordination, decreased hippocampus pyramidal cell number, decreased body weight, abnormal neurite morphology, amyloid beta deposits, premature death Allele Detail: Transgenic

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Cite this (MGI Cat# 5467595, RRID:MGI:5467595)

Source Database: MGI, catalog # 5467595
Genetic Background: either: (involves: 129S4/SvJaeSor * C57BL/6) or (involves: 129S4/SvJaeSor * CBA/J)
Affected Genes: Pou4f3
Genomic Alteration: tm1.1(HBEGF)Jsto
Availability: Availability unknown check source stock center
Reference: PMID:23100430
Notes: premature death, abnormal gait, decreased vestibular hair cell number, abnormal utricle morphology, abnormal motor capabilities/coordination/movement, abnormal vestibular system physiology, weight loss, abnormal vestibular hair cell stereociliary bundle morphology, abnormal vestibular hair cell morphology, circling, head bobbing Allele Detail: Targeted

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Cite this (MGI Cat# 5467971, RRID:MGI:5467971)

Source Database: MGI, catalog # 5467971
Genetic Background: involves: 129S4/SvJae * C57BL/6J * C57BL/6N
Affected Genes: Aldh2, Fancd2
Genomic Alteration: tm1a(EUCOMM)Wtsi; tm1Hou
Availability: Availability unknown check source stock center
Reference: PMID:22922648, PMID:21734703
Notes: abnormal hematopoietic stem cell physiology, decreased erythrocyte cell number, increased T cell derived lymphoma incidence, kinked tail, weight loss, increased sensitivity to xenobiotic induced morbidity/mortality, increased lymphoma incidence, increased double-positive T cell number, increased mean corpuscular volume, thrombocytopenia, decreased hematocrit, abnormal thymus morphology, lethargy, premature death, embryonic lethality during organogenesis, abnormal spleen morphology, increased acute lymphoblastic leukemia incidence, increased CD8-positive, alpha-beta T cell number, impaired hematopoiesis, exencephaly, enlarged spleen, decreased hemoglobin content, decreased erythrocyte cell number, anemia, decreased hematopoietic stem cell number, decreased hemoglobin content, decreased bone marrow cell number, decreased body weight, anophthalmia, decreased leukocyte cell number, abnormal lymphopoiesis, abnormal eye morphology, abnormal chest morphology, abnormal bone marrow cell morphology/development, anemia, extramedullary hematopoiesis, pancytopenia, increased physiological sensitivity to xenobiotic, increased sensitivity to induced cell death, decreased bone marrow cell number Allele Detail: Targeted

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Cite this (MGI Cat# 3826786, RRID:MGI:3826786)

Source Database: MGI, catalog # 3826786
Genetic Background: Not Specified
Affected Genes: Pkhd1
Genomic Alteration: tm1Gwu
Availability: Availability unknown check source stock center
Reference: PMID:18235088, PMID:18782757
Notes: premature death, dilated pancreatic duct, renal necrosis, renal fibrosis, prenatal lethality, incomplete penetrance, pancreas cysts, liver fibrosis, liver cysts, kidney cysts, hepatic necrosis, gastrointestinal ulcer, dilated renal tubules, dilated proximal convoluted tubules, abnormal renal tubule epithelial cell primary cilium morphology, dilated pancreatic duct, decreased glomerular capillary number, abnormal brain morphology, abnormal liver morphology, dilated renal tubules, abnormal papillary duct morphology, increased glomerular capsule space, mesangial cell hyperplasia Allele Detail: Targeted

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Cite this (MGI Cat# 4999865, RRID:MGI:4999865)

Source Database: MGI, catalog # 4999865
Genetic Background: either: (involves: 129P2/OlaHsd * 129S6/SvEvTac) or (involves: 129P2/OlaHsd * Black Swiss) or (involves: 129P2/OlaHsd * C57BL/6)
Affected Genes: Nfic
Genomic Alteration: tm1Rmg
Availability: Availability unknown check source stock center
Reference: PMID:12529411
Notes: long upper incisors, abnormal lower incisor morphology, abnormal dentin morphology, brittle teeth, abnormal molar socket morphology, abnormal tooth development, small mandible, reproductive system phenotype, absent lower incisors, premature death, absent molar root, abnormal tooth root development, abnormal molar morphology, abnormal upper incisor morphology, decreased body size, abnormal eating behavior Allele Detail: Targeted

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Cite this (MGI Cat# 3582548, RRID:MGI:3582548)

Source Database: MGI, catalog # 3582548
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Rb1
Genomic Alteration: tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:12498715, PMID:1406933
Notes: increased thyroid tumor incidence, premature death, cachexia, neoplasm, increased pituitary gland tumor incidence, increased pituitary gland tumor incidence Allele Detail: Targeted

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