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on page 1 showing 20 out of 1,134 results from 1 sources

Cite this (MGI Cat# 2384396, RRID:MGI:2384396)

Source Database: MGI, catalog # 2384396
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Affected Genes: Foxb1
Genomic Alteration: tm1Blh
Availability: Availability unknown check source stock center
Reference: PMID:9118797
Notes: open neural tube, postnatal lethality, incomplete penetrance, lethality throughout fetal growth and development, incomplete penetrance, decreased embryo size, limb grasping, galactostasis, decreased body size, decreased survivor rate, caudal body truncation Allele Detail: Targeted

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Cite this (MGI Cat# 2683447, RRID:MGI:2683447)

Source Database: MGI, catalog # 2683447
Genetic Background: either: 129/Sv or C57BL/6J or (involves: 129/Sv * C57BL/6J)
Affected Genes: Pparg
Genomic Alteration: tm1Auw
Availability: Availability unknown check source stock center
Reference: PMID:14603033
Notes: decreased body temperature, decreased brown adipose tissue mass, postnatal lethality, incomplete penetrance, abnormal circulating alanine transaminase level, abnormal glucose homeostasis, impaired glucose tolerance, hyperlipidemia, decreased white adipose tissue mass, increased circulating triglyceride level, increased liver triglyceride level, insulin resistance, decreased body weight, increased circulating free fatty acid level, increased circulating aspartate transaminase level, enlarged liver, abnormal brown adipose tissue morphology, hepatic steatosis, postnatal growth retardation, lipodystrophy Allele Detail: Targeted

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Cite this (MGI Cat# 3710633, RRID:MGI:3710633)

Source Database: MGI, catalog # 3710633
Genetic Background: B6.129X1-Gpd2
Affected Genes: Gpd2
Genomic Alteration: tm1Lbr
Availability: Availability unknown check source stock center
Reference: PMID:12093799
Notes: decreased epididymal fat pad weight, prenatal lethality, incomplete penetrance, homeostasis/metabolism phenotype, reduced fertility, postnatal lethality, incomplete penetrance, decreased susceptibility to weight gain, decreased parametrial fat pad weight, decreased body mass index, decreased litter size, decreased white adipose tissue amount Allele Detail: Targeted

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Cite this (MGI Cat# 3695037, RRID:MGI:3695037)

Source Database: MGI, catalog # 3695037
Genetic Background: Not Specified
Affected Genes: Glrb
Genomic Alteration: spa
Availability: Availability unknown check source stock center
Reference: PMID:8733750, PMID:4323808
Notes: abnormal gait, abnormal posture, muscle spasm, impaired swimming, postnatal lethality, incomplete penetrance, abnormal spinal nerve morphology, reduced male fertility, abnormal maternal nurturing, impaired righting response, enlarged adrenal glands, fragile skeleton, muscle spasm, abnormal spinal cord ventral horn morphology, abnormal vertebral column morphology, hemorrhage, tremors, abnormal intervertebral disk morphology, abnormal brain dura mater morphology, abnormal spinal cord morphology, abnormal adrenal cortex morphology, abnormal dorsal root ganglion morphology, edema, abnormal Purkinje cell morphology, hyperekplexia, increased startle reflex, decreased body size, short stride length Allele Detail: Spontaneous

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Cite this (MGI Cat# 3688874, RRID:MGI:3688874)

Source Database: MGI, catalog # 3688874
Genetic Background: Not Specified
Affected Genes: Egr3
Genomic Alteration: tm1Jmi
Availability: Availability unknown check source stock center
Reference: PMID:9731539, PMID:19954518, PMID:11978828
Notes: tremors, postnatal lethality, incomplete penetrance, abnormal somatic sensory system morphology, abnormal excitatory postsynaptic potential, abnormal muscle spindle morphology, abnormal dorsal root ganglion morphology, abnormal somatic nervous system physiology, ataxia, abnormal proprioceptive neuron morphology, abnormal nervous system physiology, absent muscle spindles, abnormal proprioceptive neuron morphology, decreased motor neuron number, abnormal cholinergic neuron morphology, abnormal limb posture, blepharoptosis, abnormal gait, scoliosis Allele Detail: Targeted

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Cite this (MGI Cat# 5292104, RRID:MGI:5292104)

Source Database: MGI, catalog # 5292104
Genetic Background: B6.129S4-Nrk
Affected Genes: Nrk
Genomic Alteration: tm1Mkom
Availability: Availability unknown check source stock center
Reference: PMID:21715335
Notes: dystocia, increased spongiotrophoblast size, enlarged placenta, neonatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, pregnancy-related premature death, increased placenta weight Allele Detail: Targeted

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Cite this (MGI Cat# 4821310, RRID:MGI:4821310)

Source Database: MGI, catalog # 4821310
Genetic Background: CF-1
Affected Genes:
Genomic Alteration: sb
Availability: Availability unknown check source stock center
Reference:
Notes: decreased survivor rate, kyphoscoliosis, decreased body length, abnormal spine curvature, abnormal vertebral column morphology, lordosis, abnormal thoracic cage shape, decreased thoracic vertebrae number, reduced female fertility, reduced male fertility, abnormal tail development, decreased rib number, postnatal lethality, incomplete penetrance, rib fusion, short tail, abnormal cervical vertebrae morphology, abnormal lumbar vertebrae morphology, abnormal sacral vertebrae morphology, abnormal skeleton morphology Allele Detail: Spontaneous

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Cite this (MGI Cat# 3623588, RRID:MGI:3623588)

Source Database: MGI, catalog # 3623588
Genetic Background: involves: 129 * C57BL/6
Affected Genes: Npr3
Genomic Alteration: tm1Unc
Availability: Availability unknown check source stock center
Reference: PMID:10377427
Notes: increased hematocrit, abnormal urine nucleotide level, increased length of long bones, increased osteoblast cell number, long tail, hypovolemia, hunched posture, domed cranium, polyuria, polydipsia, delayed bone ossification, decreased body weight, increased body length, small thoracic cage, dehydration, abnormal long bone epiphyseal plate proliferative zone, abnormal osteoclast morphology, decreased urine osmolality, increased erythrocyte cell number, hypotension, abnormal bone trabecula morphology, abnormal bone remodeling, increased hemoglobin content, abnormal skeleton development, abnormal blood homeostasis, reduced fertility, postnatal lethality, incomplete penetrance, increased circulating alkaline phosphatase level, elongated vertebral body, elongated metatarsal bones Allele Detail: Targeted

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Cite this (MGI Cat# 3716660, RRID:MGI:3716660)

Source Database: MGI, catalog # 3716660
Genetic Background: B6.129S7(Cg)-Pik3ca
Affected Genes: Pik3ca
Genomic Alteration: tm1Jdo
Availability: Availability unknown check source stock center
Reference: PMID:17540175
Notes: neonatal lethality, incomplete penetrance, abnormal lymphatic vessel morphology, decreased incidence of tumors by chemical induction, abnormal lymphangiogenesis, postnatal lethality, incomplete penetrance, decreased body weight, chylous ascites Allele Detail: Targeted

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Cite this (MGI Cat# 3617775, RRID:MGI:3617775)

Source Database: MGI, catalog # 3617775
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Gab1
Genomic Alteration: tm1Wbm
Availability: Availability unknown check source stock center
Reference: PMID:10995442
Notes: postnatal lethality, incomplete penetrance, abnormal behavior Allele Detail: Targeted

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Cite this (MGI Cat# 5796492, RRID:MGI:5796492)

Source Database: MGI, catalog # 5796492
Genetic Background: involves: C57BL/6 * CBA
Affected Genes:
Genomic Alteration: Tg(Pten)1Srn
Availability: Availability unknown check source stock center
Reference: PMID:22405073, PMID:26780512
Notes: abnormal cell physiology, decreased cell proliferation, abnormal brown adipose tissue morphology, decreased circulating cholesterol level, decreased circulating insulin level, decreased susceptibility to hepatic steatosis, increased adipocyte glucose uptake, decreased brown fat cell lipid droplet size, increased energy expenditure, decreased body fat mass, decreased body weight, abnormal adipose tissue morphology, decreased circulating insulin-like growth factor I level, abnormal excitatory postsynaptic potential, increased basal metabolism, decreased epididymal fat pad weight, decreased embryo size, decreased circulating leptin level, postnatal lethality, incomplete penetrance, polyphagia, increased insulin sensitivity, decreased fasted circulating glucose level, abnormal brown adipose tissue physiology, extended life span, decreased incidence of tumors by chemical induction, enhanced coordination, decreased white fat cell size Allele Detail: Transgenic

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Cite this (MGI Cat# 5497000, RRID:MGI:5497000)

Source Database: MGI, catalog # 5497000
Genetic Background: involves: 129S1/Sv * C57BL/6J
Affected Genes: Slc6a4, Slc18a2
Genomic Alteration: tm1.1Bgir; tm1(cre)Xz
Availability: Availability unknown check source stock center
Reference: PMID:21814181
Notes: nervous system phenotype, postnatal lethality, incomplete penetrance, decreased anxiety-related response, abnormal emotion/affect behavior, abnormal catecholamine level, decreased serotonin level, hypoactivity Allele Detail: Targeted

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Cite this (MGI Cat# 5896655, RRID:MGI:5896655)

Source Database: MGI, catalog # 5896655
Genetic Background: involves: 129S2/SvPas * C57BL/6J * C57BL/6N
Affected Genes: Emx1, Brpf1
Genomic Alteration: tm1c(EUCOMM)Wtsi; tm1(cre)Krj
Availability: Availability unknown check source stock center
Reference: PMID:25757017, PMID:25568313, PMID:27939640
Notes: decreased neuronal precursor proliferation, abnormal hippocampus CA1 region morphology, increased subiculum size, abnormal hippocampus region morphology, abnormal hippocampus pyramidal cell layer, decreased radial glial cell number, abnormal hippocampus development, abnormal hippocampal mossy fiber morphology, abnormal hippocampus morphology, abnormal neocortex morphology, abnormal neuronal migration, decreased dentate gyrus size, postnatal lethality, incomplete penetrance, abnormal corpus callosum morphology, abnormal neuronal stem cell morphology, decreased neuronal precursor cell number, abnormal cell cycle checkpoint function, abnormal hippocampus neuron morphology, abnormal radial glial cell morphology, abnormal dentate gyrus morphology, abnormal behavior, decreased neuronal precursor proliferation, limb grasping, abnormal nest building behavior, decreased neocortex size, decreased food intake, decreased corpus callosum size, decreased body size, abnormal neocortex morphology, prenatal lethality, incomplete penetrance, nervous system phenotype, postnatal lethality, incomplete penetrance, prenatal growth retardation, thin cortical plate, abnormal cell physiology Allele Detail: Targeted

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Cite this (MGI Cat# 2448446, RRID:MGI:2448446)

Source Database: MGI, catalog # 2448446
Genetic Background: involves: DBA/1J
Affected Genes: Spta1
Genomic Alteration: sph-ha
Availability: Availability unknown check source stock center
Reference: PMID:6234993
Notes: abnormal erythrocyte morphology, hemolytic anemia, enlarged liver, abnormal reticulocyte morphology, infertility, decreased hematocrit, postnatal lethality, incomplete penetrance, decreased hemoglobin content, jaundice, abnormal skin pigmentation, erythroblastosis, enlarged spleen, hypochromic microcytic anemia, prenatal lethality, incomplete penetrance, microcytosis, microcytic anemia, postnatal lethality, incomplete penetrance, cardiac hypertrophy, decreased mean corpuscular volume, enlarged spleen, jaundice, abnormal bone marrow morphology, jaundice Allele Detail: Spontaneous

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Cite this (MGI Cat# 3626194, RRID:MGI:3626194)

Source Database: MGI, catalog # 3626194
Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Affected Genes: Ep300
Genomic Alteration: tm3Pkb
Availability: Availability unknown check source stock center
Reference: PMID:16237459
Notes: postnatal lethality, incomplete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 5766740, RRID:MGI:5766740)

Source Database: MGI, catalog # 5766740
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cJ
Affected Genes: Cftr
Genomic Alteration: tm1Hsc
Availability: Availability unknown check source stock center
Reference: PMID:8589719, PMID:11102538
Notes: postnatal lethality, incomplete penetrance, abnormal intestine physiology Allele Detail: Targeted

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Cite this (MGI Cat# 4999807, RRID:MGI:4999807)

Source Database: MGI, catalog # 4999807
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * ICR
Affected Genes: Nek7
Genomic Alteration: tm1Mot
Availability: Availability unknown check source stock center
Reference: PMID:20473324
Notes: postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, binucleate, polyploidy, embryonic lethality during organogenesis, incomplete penetrance, decreased birth weight, chromosomal instability, postnatal growth retardation, perinatal lethality, incomplete penetrance, aneuploidy, abnormal mitosis, lethality throughout fetal growth and development, incomplete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 2447790, RRID:MGI:2447790)

Source Database: MGI, catalog # 2447790
Genetic Background: involves: 129 * C57BL/6J
Affected Genes: Adcyap1r1
Genomic Alteration: tm1Bbt
Availability: Availability unknown check source stock center
Reference: PMID:11193864, PMID:10792006, PMID:11425915, PMID:11792830
Notes: increased circulating insulin level, shortened circadian behavior period, prolonged diestrus, impaired glucose tolerance, decreased circulating insulin level, delayed circadian behavior phase, postnatal lethality, incomplete penetrance, reduced female fertility, increased susceptibility to bacterial infection, prolonged estrous cycle, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 5442772, RRID:MGI:5442772)

Source Database: MGI, catalog # 5442772
Genetic Background: either: (involves: 129P2/OlaHsd * C57BL/6) or B6.129P2-Tph2
Affected Genes: Tph2
Genomic Alteration: tm1Pasq
Availability: Availability unknown check source stock center
Reference: PMID:23007167
Notes: behavior/neurological phenotype, postnatal growth retardation, postnatal lethality, incomplete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 2175201, RRID:MGI:2175201)

Source Database: MGI, catalog # 2175201
Genetic Background: Not Specified
Affected Genes: Pax6
Genomic Alteration: Sey-2H
Availability: Availability unknown check source stock center
Reference:
Notes: exencephaly, postnatal lethality, incomplete penetrance, perinatal lethality, incomplete penetrance, decreased birth body size, embryonic lethality, incomplete penetrance, white spotting Allele Detail: Chemically and radiation induced

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