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on page 1 showing 20 out of 1,313 results from 1 sources

Cite this (MGI Cat# 4999766, RRID:MGI:4999766)

Source Database: MGI, catalog # 4999766
Genetic Background: involves: 129 * C57BL/6
Affected Genes: Slc39a14
Genomic Alteration: tm1Thir
Availability: Availability unknown check source stock center
Reference: PMID:21445361
Notes: decreased length of long bones, abnormal growth hormone level, abnormal liver zinc level, decreased body size, decreased body weight, decreased bone mineral density, decreased bone volume, decreased circulating insulin-like growth factor I level, decreased bone trabecula number, abnormal gluconeogenesis, short tibia, torticollis, increased bone trabecular spacing, abnormal chondrocyte differentiation, short femur, scoliosis, postnatal growth retardation, osteoporosis Allele Detail: Targeted

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Cite this (MGI Cat# 5140928, RRID:MGI:5140928)

Source Database: MGI, catalog # 5140928
Genetic Background: involves: 129S4/SvJae * 129S4/SvJaeSor * C57BL/6
Affected Genes: Pdgfrb
Genomic Alteration: Tg(Prm-cre)70Og; tm14(Pdgfrb)Sor
Availability: Availability unknown check source stock center
Reference: PMID:21664579
Notes: postnatal lethality, complete penetrance, postnatal growth retardation Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2657159, RRID:MGI:2657159)

Source Database: MGI, catalog # 2657159
Genetic Background: involves: 129S4/SvJae * BALB/c
Affected Genes: Dnmt1
Genomic Alteration: tm3Jae; tm2Enl
Availability: Availability unknown check source stock center
Reference: PMID:12702876
Notes: postnatal growth retardation, increased tumor incidence, reproductive system phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 5007926, RRID:MGI:5007926)

Source Database: MGI, catalog # 5007926
Genetic Background: B6.129S6-Mefv
Affected Genes: Mefv
Genomic Alteration: tm3.1(MEFV)Chae
Availability: Availability unknown check source stock center
Reference: PMID:21600797
Notes: increased leukocyte cell number, arthritis, cachexia, decreased body weight, dermatitis, increased inflammatory response, postnatal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 5583018, RRID:MGI:5583018)

Source Database: MGI, catalog # 5583018
Genetic Background: involves: C57BL/6 * CBA
Affected Genes:
Genomic Alteration: Tg(IVL-KLK5)#Hov
Availability: Availability unknown check source stock center
Reference: PMID:24534191
Notes: skin inflammation, excessive scratching, increased pruritus, lymph node inflammation, parakeratosis, abnormal enzyme/coenzyme activity, abnormal coat appearance, acanthosis, abnormal vibrissa morphology, abnormal skin appearance, enlarged spleen, decreased hair follicle number, abnormal epidermal layer morphology, kinked vibrissae, postnatal growth retardation, hyperkeratosis, scaly skin, sparse vibrissae, sparse hair, short vibrissae, impaired skin barrier function, abnormal inguinal lymph node morphology, abnormal hair follicle morphology, abnormal dermis papillary layer morphology, abnormal circulating cytokine level, decreased birth body size, delayed hair appearance, dry skin, enlarged lymph nodes, increased IgE level, increased activated T cell number, erythroderma Allele Detail: Transgenic

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Cite this (MGI Cat# 2679917, RRID:MGI:2679917)

Source Database: MGI, catalog # 2679917
Genetic Background: involves: 129X1/SvJ
Affected Genes: Foxj1
Genomic Alteration: tm1Slb
Availability: Availability unknown check source stock center
Reference: PMID:10873152, PMID:21745638, PMID:19906869, PMID:22357932
Notes: absent respiratory motile cilia, abnormal postnatal subventricular zone morphology, abnormal brain ependyma morphology, abnormal brain development, hydroencephaly, postnatal lethality, complete penetrance, postnatal lethality, complete penetrance, small olfactory bulb, transposition of great arteries, abnormal olfactory bulb development, absent nodal flow, astrocytosis, absent oviduct epithelium motile cilium, dilated lateral ventricles, postnatal growth retardation, abnormal embryonic cilium location or orientation, dextrocardia, situs inversus, hydroencephaly, decreased embryonic cilium length, absent brain ependyma motile cilia, abnormal primitive node morphology, abnormal brain ventricle morphology Allele Detail: Targeted

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Cite this (MGI Cat# 2683447, RRID:MGI:2683447)

Source Database: MGI, catalog # 2683447
Genetic Background: either: 129/Sv or C57BL/6J or (involves: 129/Sv * C57BL/6J)
Affected Genes: Pparg
Genomic Alteration: tm1Auw
Availability: Availability unknown check source stock center
Reference: PMID:14603033
Notes: decreased brown adipose tissue mass, hepatic steatosis, increased circulating aspartate transaminase level, decreased body temperature, postnatal lethality, incomplete penetrance, hyperlipidemia, abnormal circulating alanine transaminase level, increased circulating triglyceride level, impaired glucose tolerance, abnormal glucose homeostasis, increased liver triglyceride level, increased circulating free fatty acid level, postnatal growth retardation, decreased body weight, decreased white adipose tissue mass, enlarged liver, abnormal brown adipose tissue morphology, lipodystrophy, insulin resistance Allele Detail: Targeted

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Cite this (MGI Cat# 3641262, RRID:MGI:3641262)

Source Database: MGI, catalog # 3641262
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Affected Genes: Atp2b2, Pparg
Genomic Alteration: tm2Mae; m1Mae
Availability: Availability unknown check source stock center
Reference: PMID:16845470
Notes: abnormal vibrissae reflex, abnormal blinking, decreased body size, tremors, abnormal motor coordination/balance, absent startle reflex, abnormal gait, impaired righting response, impaired balance, ataxia, abnormal reflex, decreased grip strength, head bobbing, impaired hearing, absent pinna reflex, postnatal growth retardation, abnormal prepulse inhibition Allele Detail: Targeted, Spontaneous

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Cite this (MGI Cat# 3693851, RRID:MGI:3693851)

Source Database: MGI, catalog # 3693851
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Ckb, Ckmt1
Genomic Alteration: tm2Bew; tm1Bew
Availability: Availability unknown check source stock center
Reference: PMID:15639173
Notes: decreased body weight, decreased brain size, abnormal hippocampal mossy fiber morphology, abnormal spatial learning, small hippocampus, decreased startle reflex, decreased brain weight, postnatal growth retardation, abnormal nest building behavior Allele Detail: Targeted

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Cite this (MGI Cat# 3696369, RRID:MGI:3696369)

Source Database: MGI, catalog # 3696369
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB
Affected Genes: Xpa, Ercc2
Genomic Alteration: tm3Jhjh; tm1Hvs
Availability: Availability unknown check source stock center
Reference: PMID:16904611
Notes: ataxia, postnatal growth retardation, impaired balance, postnatal lethality, complete penetrance, tremors, Purkinje cell degeneration Allele Detail: Targeted

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Cite this (MGI Cat# 3625034, RRID:MGI:3625034)

Source Database: MGI, catalog # 3625034
Genetic Background: Not Specified
Affected Genes: Pmp22
Genomic Alteration: tm1Lnot
Availability: Availability unknown check source stock center
Reference: PMID:16436605
Notes: abnormal Schwann cell morphology, abnormal myelin sheath morphology, abnormal neuron morphology, abnormal axon morphology, abnormal gait, abnormal sexual interaction, hindlimb paralysis, muscle weakness, postnatal growth retardation, demyelination, tremors, limb grasping Allele Detail: Targeted

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Cite this (MGI Cat# 3525103, RRID:MGI:3525103)

Source Database: MGI, catalog # 3525103
Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Affected Genes: Npr2
Genomic Alteration: tm1Gar
Availability: Availability unknown check source stock center
Reference: PMID:15572448
Notes: long upper incisors, premature death, small uterus, absent estrous cycle, absent corpus luteum, small ovary, thin uterine horn, decreased long bone epiphyseal plate size, abnormal skeleton development, decreased body size, postnatal growth retardation, abnormal uterus morphology, thin myometrium, malocclusion, long incisors, abnormal cranium morphology, cardiovascular system phenotype, decreased width of hypertrophic chondrocyte zone, thin endometrium, female infertility, long lower incisors, limb grasping Allele Detail: Targeted

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Cite this (MGI Cat# 2175844, RRID:MGI:2175844)

Source Database: MGI, catalog # 2175844
Genetic Background: involves: 129S2/SvPas * CD-1
Affected Genes: Egfr
Genomic Alteration: tm1Mag
Availability: Availability unknown check source stock center
Reference: PMID:7618084
Notes: abnormal tongue morphology, curly vibrissae, wavy vibrissae, abnormal hair follicle inner root sheath morphology, abnormal lung development, abnormal coat appearance, abnormal esophageal epithelium morphology, decreased brain size, abnormal olfactory bulb morphology, abnormal colon morphology, cachexia, abnormal hepatocyte morphology, decreased Purkinje cell number, abnormal cerebellum external granule cell layer morphology, absent eyelids, abnormal cerebral cortex morphology, small cerebellum, thin cerebral cortex, eyelids open at birth, increased circulating creatinine level, increased blood urea nitrogen level, dilated kidney collecting duct, abnormal liver morphology, postnatal growth retardation, abnormal filiform papillae morphology, abnormal fungiform papillae morphology, abnormal hair follicle development, perinatal lethality, complete penetrance, distorted hair follicle pattern, delayed hair appearance, abnormal hair shaft morphology, abnormal hair follicle orientation Allele Detail: Targeted

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Cite this (MGI Cat# 3790970, RRID:MGI:3790970)

Source Database: MGI, catalog # 3790970
Genetic Background: NOD.Cg-Vdr/CmatJ
Affected Genes: Vdr
Genomic Alteration: tm1Ska
Availability: Availability unknown check source stock center
Reference: PMID:17959935
Notes: postnatal growth retardation, decreased regulatory T cell number, decreased bone mineral density, abnormal T cell number, increased long bone epiphyseal plate size, increased susceptibility to autoimmune diabetes, decreased circulating calcium level, abnormal dendritic cell differentiation, abnormal glucose tolerance, decreased interleukin-6 secretion, abnormal interleukin-1 secretion, alopecia, abnormal chemokine secretion Allele Detail: Targeted

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Cite this (MGI Cat# 5501521, RRID:MGI:5501521)

Source Database: MGI, catalog # 5501521
Genetic Background: involves: C57BL/6 * CBA/JNCrlj * SJL
Affected Genes: Vdr
Genomic Alteration: tm1.1Pcn
Availability: Availability unknown check source stock center
Reference: PMID:23389957
Notes: increased osteoid volume, disorganized long bone epiphyseal plate, abnormal bone ossification, abnormal vitamin D level, alopecia, decreased circulating calcium level, weight loss, decreased circulating phosphate level, premature death, postnatal growth retardation, increased activity of parathyroid Allele Detail: Targeted

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Cite this (MGI Cat# 3653638, RRID:MGI:3653638)

Source Database: MGI, catalog # 3653638
Genetic Background: involves: C3H/HeJ * C57BL/6J
Affected Genes: Kl
Genomic Alteration: kl
Availability: Availability unknown check source stock center
Reference: PMID:12475907, PMID:11016890, PMID:12446599
Notes: abnormal long term object recognition memory, abnormal nervous system physiology, abnormal contextual conditioning behavior, oxidative stress, increased insulin sensitivity, decreased insulin secretion, hypoglycemia, short femur, decreased body weight, abnormal cued conditioning behavior, decreased circulating insulin level, decreased osteoclast cell number, osteopetrosis, premature death, postnatal growth retardation, decreased B cell number Allele Detail: Transgenic

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Cite this (MGI Cat# 3606961, RRID:MGI:3606961)

Source Database: MGI, catalog # 3606961
Genetic Background: involves: FVB/N
Affected Genes:
Genomic Alteration: Tg(KRT14-HPV16E7)2304Plam
Availability: Availability unknown check source stock center
Reference: PMID:8627712
Notes: postnatal growth retardation, cataract Allele Detail: Transgenic

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Cite this (MGI Cat# 3809773, RRID:MGI:3809773)

Source Database: MGI, catalog # 3809773
Genetic Background: involves: 129 * C57BL/6 * CD-1
Affected Genes: Tg(Camk2a-tTA)1Mmay, Psmc1
Genomic Alteration: tm1Maye; Tg(Camk2a-tTA)1Mmay; Tg(tetO-cre)1Lin
Availability: Availability unknown check source stock center
Reference: PMID:18701681
Notes: loss of cortex neurons, thin cerebral cortex, postnatal growth retardation, abnormal spatial learning, abnormal fear/anxiety-related behavior, forebrain atrophy, increased neuron apoptosis, neurodegeneration, alpha-synuclein inclusion body, abnormal eating behavior, enlarged brain ventricles, gliosis, premature death Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 5790646, RRID:MGI:5790646)

Source Database: MGI, catalog # 5790646
Genetic Background: involves: BALB/cAnNHsd * C3H/HeNHsd
Affected Genes: Gnptab
Genomic Alteration: nym
Availability: Availability unknown check source stock center
Reference: PMID:25107912
Notes: limb grasping, penis prolapse, decreased body size, ataxia, abnormal spine curvature, flattened snout, Purkinje cell axonal dystrophy, astrocytosis, abnormal skeleton morphology, progressive muscle weakness, abnormal gait, impaired coordination, abnormal chondrocyte morphology, thick skin, abnormal facial morphology, decreased survivor rate, abnormal cognition, Purkinje cell degeneration, abnormal fertility/fecundity, lysosomal protein accumulation, brain inflammation, abnormal pancreatic acinar cell morphology, abnormal pancreas morphology, abnormal hippocampus CA3 region morphology, decreased brain size, cerebellum atrophy, prenatal lethality, incomplete penetrance, abnormal skin turgor, brain atrophy, small nasal bridge, kyphosis, postnatal growth retardation, premature death, abnormal hippocampus CA1 region morphology, thick eyelids, abnormal cerebellum white matter morphology, abnormal cerebellar cortex morphology, abnormal cerebellar molecular layer, demyelination, axonal spheroids, abnormal enzyme/coenzyme activity Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 4999807, RRID:MGI:4999807)

Source Database: MGI, catalog # 4999807
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * ICR
Affected Genes: Nek7
Genomic Alteration: tm1Mot
Availability: Availability unknown check source stock center
Reference: PMID:20473324
Notes: preweaning lethality, complete penetrance, binucleate, decreased birth weight, abnormal mitosis, lethality throughout fetal growth and development, incomplete penetrance, chromosomal instability, aneuploidy, polyploidy, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, embryonic lethality during organogenesis, incomplete penetrance, postnatal growth retardation Allele Detail: Targeted

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