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on page 1 showing 20 out of 1,113 results from 1 sources

Cite this (MGI Cat# 4881714, RRID:MGI:4881714)

Source Database: MGI, catalog # 4881714
Genetic Background: involves: 129S/SvEv * BALB/cJ * C57BL/6
Affected Genes: Ackr3
Genomic Alteration: tm1.1Twb
Availability: Availability unknown check source stock center
Reference: PMID:21246655
Notes: cyanosis, hemorrhage, neonatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, respiratory distress, abnormal heart and great artery attachment, dilated heart atrium, enlarged heart, thick pulmonary valve, abnormal atrioventricular cushion morphology, abnormal cardiovascular system physiology, aortic valve stenosis, overriding aortic valve, perimembraneous ventricular septal defect, pulmonary valve stenosis, thick aortic valve, abnormal semilunar valve morphology Allele Detail: Targeted

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Cite this (MGI Cat# 3040322, RRID:MGI:3040322)

Source Database: MGI, catalog # 3040322
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Affected Genes: Cyr61
Genomic Alteration: tm1Lfl
Availability: Availability unknown check source stock center
Reference: PMID:12446788, PMID:17023674
Notes: pale placenta, abnormal chorionic plate morphology, embryonic lethality during organogenesis, incomplete penetrance, neonatal lethality, complete penetrance, failure of chorioallantoic fusion, abnormal placenta morphology, abnormal placental labyrinth vasculature morphology, hemorrhage, abnormal dorsal aorta morphology, abnormal artery morphology, abnormal apoptosis, complete atrioventricular septal defect, ventricular septal defect, failure of atrioventricular cushion closure, common atrioventricular valve, abnormal interventricular septum morphology, abnormal heart development, dilated dorsal aorta Allele Detail: Targeted

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Cite this (MGI Cat# 3797591, RRID:MGI:3797591)

Source Database: MGI, catalog # 3797591
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Phox2b
Genomic Alteration: tm2Jbr
Availability: Availability unknown check source stock center
Reference: PMID:18198276
Notes: abnormal breathing pattern, abnormal lung volume, abnormal respiration, apnea, cyanosis, abnormal brain interneuron morphology, hypoventilation, neonatal lethality, complete penetrance, respiratory failure Allele Detail: Targeted

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Cite this (MGI Cat# 2175079, RRID:MGI:2175079)

Source Database: MGI, catalog # 2175079
Genetic Background: involves: 129S/SvEv
Affected Genes: Igf1r
Genomic Alteration: tm1Arge
Availability: Availability unknown check source stock center
Reference: PMID:8402901
Notes: abnormal brainstem morphology, thin epidermis, abnormal hair follicle morphology, atelectasis, cyanosis, decreased oligodendrocyte progenitor number, small hair follicles, thin epidermis stratum spinosum, decreased birth weight, neonatal lethality, complete penetrance, respiratory failure, muscle hypoplasia, delayed bone ossification, abnormal spinal cord morphology, translucent skin, decreased hair follicle number Allele Detail: Targeted

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Cite this (MGI Cat# 3037267, RRID:MGI:3037267)

Source Database: MGI, catalog # 3037267
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Pou2f2
Genomic Alteration: tm1Bal
Availability: Availability unknown check source stock center
Reference: PMID:14978099
Notes: decreased B cell number, decreased immunoglobulin level, neonatal lethality, complete penetrance, arrested B cell differentiation Allele Detail: Targeted

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Cite this (MGI Cat# 2175131, RRID:MGI:2175131)

Source Database: MGI, catalog # 2175131
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Myf6
Genomic Alteration: tm1Wb
Availability: Availability unknown check source stock center
Reference: PMID:7588068
Notes: abnormal cervical vertebrae morphology, abnormal intercostal muscle morphology, abnormal myotome morphology, abnormal sternocostal joint morphology, abnormal sternum ossification, rib bifurcation, rib fusion, short ribs, truncated ribs, neonatal lethality, complete penetrance, abnormal rib morphology, abnormal myotome development, respiratory distress Allele Detail: Targeted

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Cite this (MGI Cat# 3054527, RRID:MGI:3054527)

Source Database: MGI, catalog # 3054527
Genetic Background: involves: FVB
Affected Genes:
Genomic Alteration: Tg(DM15)26Bew
Availability: Availability unknown check source stock center
Reference: PMID:15317754, PMID:8673131
Notes: abnormal P wave, decreased food intake, abnormal impulse conducting system conduction, abnormal motor coordination/ balance, abnormal muscle relaxation, abnormal myocardial fiber morphology, abnormal skeletal muscle fiber morphology, thick interventricular septum, cardiac interstitial fibrosis, cardiomyopathy, dystrophic muscle, hypotension, irregular heartbeat, heart left ventricle hypertrophy, myopathy, thick ventricular wall, abnormal myocardial fiber morphology, cardiomyopathy, hunched posture, neonatal lethality, complete penetrance, decreased food intake, abnormal hair texture, pregnancy-related premature death, centrally nucleated skeletal muscle fibers, increased variability of skeletal muscle fiber size Allele Detail: Transgenic

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Cite this (MGI Cat# 2183210, RRID:MGI:2183210)

Source Database: MGI, catalog # 2183210
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Ascl1
Genomic Alteration: tm1And
Availability: Availability unknown check source stock center
Reference: PMID:8221886
Notes: neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 5301973, RRID:MGI:5301973)

Source Database: MGI, catalog # 5301973
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Affected Genes: Lmnb1, Lmnb2
Genomic Alteration: tm1Yxz
Availability: Availability unknown check source stock center
Reference: PMID:22116031
Notes: abnormal cell physiology, abnormal pulmonary alveolus morphology, neonatal lethality, complete penetrance, decreased embryo size, decreased fetal size, respiratory failure, thin diaphragm muscle, abnormal phrenic nerve innervation pattern to diaphragm, abnormal neuron differentiation, abnormal neuronal migration, abnormal neuronal precursor proliferation, abnormal stratification in cerebral cortex, increased neuronal precursor cell number, microcephaly, thin cerebral cortex Allele Detail: Targeted

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Cite this (MGI Cat# 2175049, RRID:MGI:2175049)

Source Database: MGI, catalog # 2175049
Genetic Background: either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6)
Affected Genes: Grin1
Genomic Alteration: tm1Stl
Availability: Availability unknown check source stock center
Reference: PMID:8313466
Notes: neonatal lethality, complete penetrance, ataxia, abnormal suckling behavior, apnea, cyanosis, abnormal brainstem morphology, absence of NMDA-mediated synaptic currents Allele Detail: Targeted

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Cite this (MGI Cat# 4437276, RRID:MGI:4437276)

Source Database: MGI, catalog # 4437276
Genetic Background: FVB.C-Prdm16
Affected Genes: Prdm16
Genomic Alteration: csp1
Availability: Availability unknown check source stock center
Reference: PMID:20007998
Notes: narrow snout, narrow maxilla, cleft secondary palate, abnormal tongue morphology, respiratory distress, distended abdomen, neonatal lethality, complete penetrance, respiratory failure, abnormal palatal shelf elevation, short snout, abnormal snout morphology, abnormal nasal bone morphology, short nasal bone, short maxilla, small mandible, short Meckel's cartilage, micrognathia, mandible hypoplasia, abnormal mandible morphology, premature bone ossification, abnormal choroid plexus morphology, abnormal sublingual duct morphology, abnormal submandibular duct morphology, abnormal sublingual gland morphology, submandibular gland hypoplasia, abnormal retina morphology, small lung, abnormal lung morphology, abnormal heart ventricle morphology, abnormal heart morphology, ventricular hypoplasia, pulmonary hypoplasia Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 2172287, RRID:MGI:2172287)

Source Database: MGI, catalog # 2172287
Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Affected Genes: Fgf9
Genomic Alteration: tm1Dor
Availability: Availability unknown check source stock center
Reference: PMID:11493531, PMID:16308329, PMID:18653563, PMID:11290325
Notes: cleft palate, abnormal cecum morphology, abnormal digestive system physiology, abnormal small intestine crypts of Lieberkuhn morphology, abnormal small intestine morphology, disorganized testis cords, abnormal mesenchymal cell proliferation involved in lung development, cyanosis, decreased fetal weight, dilated heart atrium, dilated heart ventricle, hypoxia, respiratory failure, neonatal lethality, complete penetrance, abnormal testis morphology, epididymis hypoplasia, abnormal Sertoli cell development, abnormal testis cord formation, endocrine/exocrine gland phenotype, abnormal Leydig cell differentiation, decreased number of peritubular myoid cells, pulmonary hypoplasia, perinatal lethality, complete penetrance, abnormal branching involved in lung morphogenesis, decreased lung weight, abnormal primary sex determination, ovotestis, primary sex reversal, testis hypoplasia Allele Detail: Targeted

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Cite this (MGI Cat# 3701801, RRID:MGI:3701801)

Source Database: MGI, catalog # 3701801
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Ptges3
Genomic Alteration: Gt(W069F07)Wrst
Availability: Availability unknown check source stock center
Reference: PMID:17000766
Notes: abnormal breathing pattern, atelectasis, pale lung, abnormal surfactant secretion, impaired lung alveolus development, abnormal skin appearance, decreased type II pneumocyte number, impaired skin barrier function, lethargy, neonatal lethality, complete penetrance, shiny skin, small lung Allele Detail: Gene trapped

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Cite this (MGI Cat# 2170585, RRID:MGI:2170585)

Source Database: MGI, catalog # 2170585
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Hoxa2, Hoxa1
Genomic Alteration: tm2Mrc; tm1Mrc
Availability: Availability unknown check source stock center
Reference: PMID:10529419
Notes: abnormal hindbrain morphology, abnormal middle ear ossicle morphology, absent outer ear, neonatal lethality, complete penetrance, small middle ear ossicles Allele Detail: Targeted

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Cite this (MGI Cat# 3809892, RRID:MGI:3809892)

Source Database: MGI, catalog # 3809892
Genetic Background: Not Specified
Affected Genes: Dlx6
Genomic Alteration: tm1Jlr
Availability: Availability unknown check source stock center
Reference: PMID:18697905
Notes: decreased tympanic ring size, aerophagia, abnormal gonial bone morphology, craniofacial phenotype, small mandible, neonatal lethality, complete penetrance, mandibular condyloid process hypoplasia, absent mandibular coronoid process Allele Detail: Targeted

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Cite this (MGI Cat# 5570667, RRID:MGI:5570667)

Source Database: MGI, catalog # 5570667
Genetic Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj
Affected Genes: Runx2
Genomic Alteration: Tg(Col2a1-cre)1Star; tm1.1Yyon
Availability: Availability unknown check source stock center
Reference: PMID:23553905
Notes: neonatal lethality, complete penetrance, delayed bone ossification, delayed endochondral bone ossification, respiratory distress Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2674287, RRID:MGI:2674287)

Source Database: MGI, catalog # 2674287
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6
Affected Genes: Meox1, Meox2
Genomic Alteration: Tg(Mx1-TAX)2627Arnh; tm1Vpa
Availability: Availability unknown check source stock center
Reference: PMID:12925591
Notes: abnormal somite development, absent ribs, absent vertebrae, decreased body length, abnormal skeletal muscle morphology, vestigial tail, neonatal lethality, complete penetrance Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3722059, RRID:MGI:3722059)

Source Database: MGI, catalog # 3722059
Genetic Background: C3HeB/FeJ-Dync1h1
Affected Genes: Dync1h1
Genomic Alteration: Cra1
Availability: Availability unknown check source stock center
Reference: PMID:12730604
Notes: aphagia, decreased spinal cord ventral horn cell number, neonatal lethality, complete penetrance, neuronal intranuclear inclusions, paralysis Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 2652468, RRID:MGI:2652468)

Source Database: MGI, catalog # 2652468
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Affected Genes: Map1b
Genomic Alteration: Gt(IRESBetageo)2Pgr
Availability: Availability unknown check source stock center
Reference: PMID:11085878
Notes: abnormal cerebellar foliation, abnormal cerebellum morphology, abnormal cerebral cortex morphology, abnormal corpus callosum morphology, abnormal dentate gyrus morphology, abnormal hippocampus morphology, abnormal limb posture, abnormal olfactory bulb morphology, absent subplate, enlarged lateral ventricles, enlarged third ventricle, neonatal lethality, complete penetrance, unresponsive to tactile stimuli Allele Detail: Gene trapped

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Cite this (MGI Cat# 3818641, RRID:MGI:3818641)

Source Database: MGI, catalog # 3818641
Genetic Background: involves: 101/Rl * C3H/Rl
Affected Genes: Tyr
Genomic Alteration: c-14CoS
Availability: Availability unknown check source stock center
Reference: PMID:7117820
Notes: neonatal lethality, complete penetrance, neonatal lethality, complete penetrance Allele Detail: Radiation induced

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