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on page 1 showing 20 out of 1,129 results

Cite this (MGI Cat# 4881714, RRID:MGI:4881714)

Source Database: MGI, catalog # 4881714
Genetic Background: involves: 129S/SvEv * BALB/cJ * C57BL/6
Affected Genes: Ackr3
Genomic Alteration: tm1.1Twb
Availability: Availability unknown check source stock center
Reference: PMID:21246655
Notes: abnormal atrioventricular cushion morphology, thick pulmonary valve, enlarged heart, thick aortic valve, pulmonary valve stenosis, perimembraneous ventricular septal defect, abnormal semilunar valve morphology, overriding aortic valve, aortic valve stenosis, abnormal cardiovascular system physiology, dilated heart atrium, abnormal heart and great artery attachment, respiratory distress, perinatal lethality, incomplete penetrance, neonatal lethality, complete penetrance, hemorrhage, cyanosis Allele Detail: Targeted

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Cite this (MGI Cat# 3040322, RRID:MGI:3040322)

Source Database: MGI, catalog # 3040322
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Affected Genes: Cyr61
Genomic Alteration: tm1Lfl
Availability: Availability unknown check source stock center
Reference: PMID:12446788, PMID:17023674
Notes: neonatal lethality, complete penetrance, dilated dorsal aorta, abnormal heart development, abnormal chorionic plate morphology, complete atrioventricular septal defect, ventricular septal defect, failure of atrioventricular cushion closure, abnormal placental labyrinth vasculature morphology, abnormal apoptosis, abnormal artery morphology, embryonic lethality during organogenesis, incomplete penetrance, abnormal dorsal aorta morphology, hemorrhage, abnormal placenta morphology, failure of chorioallantoic fusion, common atrioventricular valve, abnormal interventricular septum morphology, pale placenta Allele Detail: Targeted

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Cite this (MGI Cat# 3797591, RRID:MGI:3797591)

Source Database: MGI, catalog # 3797591
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Phox2b
Genomic Alteration: tm2Jbr
Availability: Availability unknown check source stock center
Reference: PMID:18198276
Notes: abnormal respiration, apnea, respiratory failure, abnormal lung volume, cyanosis, abnormal breathing pattern, abnormal brain interneuron morphology, neonatal lethality, complete penetrance, hypoventilation Allele Detail: Targeted

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Cite this (MGI Cat# 2175079, RRID:MGI:2175079)

Source Database: MGI, catalog # 2175079
Genetic Background: involves: 129S/SvEv
Affected Genes: Igf1r
Genomic Alteration: tm1Arge
Availability: Availability unknown check source stock center
Reference: PMID:8402901
Notes: respiratory failure, neonatal lethality, complete penetrance, small hair follicles, abnormal spinal cord morphology, translucent skin, decreased oligodendrocyte progenitor number, thin epidermis stratum spinosum, delayed bone ossification, cyanosis, decreased birth weight, atelectasis, abnormal hair follicle morphology, thin epidermis, abnormal brainstem morphology, muscle hypoplasia, decreased hair follicle number Allele Detail: Targeted

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Cite this (MGI Cat# 3037267, RRID:MGI:3037267)

Source Database: MGI, catalog # 3037267
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Pou2f2
Genomic Alteration: tm1Bal
Availability: Availability unknown check source stock center
Reference: PMID:14978099
Notes: decreased immunoglobulin level, decreased B cell number, neonatal lethality, complete penetrance, arrested B cell differentiation Allele Detail: Targeted

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Cite this (MGI Cat# 2175131, RRID:MGI:2175131)

Source Database: MGI, catalog # 2175131
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Myf6
Genomic Alteration: tm1Wb
Availability: Availability unknown check source stock center
Reference: PMID:7588068
Notes: abnormal sternum ossification, abnormal rib morphology, abnormal cervical vertebrae morphology, short ribs, neonatal lethality, complete penetrance, abnormal myotome morphology, abnormal myotome development, abnormal sternocostal joint morphology, abnormal intercostal muscle morphology, respiratory distress, rib fusion, truncated ribs, rib bifurcation Allele Detail: Targeted

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Cite this (MGI Cat# 3054527, RRID:MGI:3054527)

Source Database: MGI, catalog # 3054527
Genetic Background: involves: FVB
Affected Genes:
Genomic Alteration: Tg(DM15)26Bew
Availability: Availability unknown check source stock center
Reference: PMID:15317754, PMID:8673131
Notes: cardiomyopathy, abnormal hair texture, abnormal P wave, abnormal myocardial fiber morphology, decreased food intake, thick ventricular wall, myopathy, heart left ventricle hypertrophy, dystrophic muscle, neonatal lethality, complete penetrance, decreased food intake, abnormal myocardial fiber morphology, hypotension, hunched posture, increased variability of skeletal muscle fiber size, abnormal motor coordination/balance, pregnancy-related premature death, abnormal impulse conducting system conduction, abnormal muscle relaxation, cardiac interstitial fibrosis, abnormal skeletal muscle fiber morphology, thick interventricular septum, irregular heartbeat, cardiomyopathy, centrally nucleated skeletal muscle fibers Allele Detail: Transgenic

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Cite this (MGI Cat# 2183210, RRID:MGI:2183210)

Source Database: MGI, catalog # 2183210
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Ascl1
Genomic Alteration: tm1And
Availability: Availability unknown check source stock center
Reference: PMID:8221886
Notes: neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 3621037, RRID:MGI:3621037)

Source Database: MGI, catalog # 3621037
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
Affected Genes: Gja1
Genomic Alteration: tm1Kdr; tm1.1Kwi
Availability: Availability unknown check source stock center
Reference: PMID:11135457
Notes: neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 5301973, RRID:MGI:5301973)

Source Database: MGI, catalog # 5301973
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Affected Genes: Lmnb1, Lmnb2
Genomic Alteration: tm1Yxz
Availability: Availability unknown check source stock center
Reference: PMID:22116031
Notes: decreased fetal size, thin cerebral cortex, abnormal neuron differentiation, abnormal phrenic nerve innervation pattern to diaphragm, thin diaphragm muscle, respiratory failure, microcephaly, increased neuronal precursor cell number, abnormal pulmonary alveolus morphology, neonatal lethality, complete penetrance, decreased embryo size, abnormal neuronal migration, abnormal neuronal precursor proliferation, abnormal stratification in cerebral cortex, abnormal cell physiology Allele Detail: Targeted

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Cite this (MGI Cat# 2175049, RRID:MGI:2175049)

Source Database: MGI, catalog # 2175049
Genetic Background: either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6)
Affected Genes: Grin1
Genomic Alteration: tm1Stl
Availability: Availability unknown check source stock center
Reference: PMID:8313466
Notes: neonatal lethality, complete penetrance, cyanosis, apnea, abnormal suckling behavior, ataxia, abnormal brainstem morphology, absence of NMDA-mediated synaptic currents Allele Detail: Targeted

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Cite this (MGI Cat# 4437276, RRID:MGI:4437276)

Source Database: MGI, catalog # 4437276
Genetic Background: FVB.C-Prdm16
Affected Genes: Prdm16
Genomic Alteration: csp1
Availability: Availability unknown check source stock center
Reference: PMID:20007998
Notes: cleft secondary palate, neonatal lethality, complete penetrance, abnormal heart morphology, ventricular hypoplasia, pulmonary hypoplasia, respiratory failure, abnormal tongue morphology, submandibular gland hypoplasia, abnormal heart ventricle morphology, abnormal lung morphology, distended abdomen, abnormal retina morphology, short maxilla, respiratory distress, abnormal sublingual gland morphology, narrow snout, short Meckel's cartilage, abnormal sublingual duct morphology, abnormal choroid plexus morphology, premature bone ossification, abnormal mandible morphology, mandible hypoplasia, micrognathia, small mandible, short nasal bone, abnormal nasal bone morphology, abnormal snout morphology, short snout, abnormal submandibular duct morphology, narrow maxilla, abnormal palatal shelf elevation, small lung Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 2172287, RRID:MGI:2172287)

Source Database: MGI, catalog # 2172287
Genetic Background: involves: 129S6/SvEvTac * C57BL/6
Affected Genes: Fgf9
Genomic Alteration: tm1Dor
Availability: Availability unknown check source stock center
Reference: PMID:11493531, PMID:18653563, PMID:16308329, PMID:11290325
Notes: abnormal small intestine crypts of Lieberkuhn morphology, decreased number of peritubular myoid cells, abnormal testis morphology, decreased fetal weight, dilated heart atrium, dilated heart ventricle, decreased lung weight, abnormal cecum morphology, epididymis hypoplasia, abnormal Sertoli cell development, abnormal testis cord formation, cleft palate, abnormal branching involved in lung morphogenesis, ovotestis, abnormal mesenchymal cell proliferation involved in lung development, cyanosis, respiratory failure, pulmonary hypoplasia, perinatal lethality, complete penetrance, neonatal lethality, complete penetrance, abnormal small intestine morphology, disorganized testis cords, abnormal digestive system physiology, primary sex reversal, hypoxia, abnormal primary sex determination, testis hypoplasia, endocrine/exocrine gland phenotype, abnormal Leydig cell differentiation Allele Detail: Targeted

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Cite this (MGI Cat# 3701801, RRID:MGI:3701801)

Source Database: MGI, catalog # 3701801
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Ptges3
Genomic Alteration: Gt(W069F07)Wrst
Availability: Availability unknown check source stock center
Reference: PMID:17000766
Notes: atelectasis, small lung, abnormal breathing pattern, pale lung, abnormal surfactant secretion, impaired lung alveolus development, abnormal skin appearance, decreased type II pneumocyte number, impaired skin barrier function, lethargy, neonatal lethality, complete penetrance, shiny skin Allele Detail: Gene trapped

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Cite this (MGI Cat# 2170585, RRID:MGI:2170585)

Source Database: MGI, catalog # 2170585
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Hoxa2, Hoxa1
Genomic Alteration: tm2Mrc; tm1Mrc
Availability: Availability unknown check source stock center
Reference: PMID:10529419
Notes: neonatal lethality, complete penetrance, small middle ear ossicles, abnormal middle ear ossicle morphology, abnormal hindbrain morphology, absent outer ear Allele Detail: Targeted

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Cite this (MGI Cat# 3809892, RRID:MGI:3809892)

Source Database: MGI, catalog # 3809892
Genetic Background: Not Specified
Affected Genes: Dlx6
Genomic Alteration: tm1Jlr
Availability: Availability unknown check source stock center
Reference: PMID:18697905
Notes: aerophagia, mandibular condyloid process hypoplasia, absent mandibular coronoid process, craniofacial phenotype, small mandible, neonatal lethality, complete penetrance, decreased tympanic ring size, abnormal gonial bone morphology Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 5902457, RRID:MGI:5902457)

Source Database: MGI, catalog # 5902457
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * C57BL/6J * CBA/J
Affected Genes: H2afv, Mapk1
Genomic Alteration: tm1Gela; Tg(Wnt1-cre)11Rth
Availability: Availability unknown check source stock center
Reference: PMID:26395480
Notes: abnormal Meckel's cartilage morphology, failure of palatal shelf elevation, maxilla hypoplasia, abnormal mandible morphology, neonatal lethality, complete penetrance, small mandibular condyloid process, cleft palate, micrognathia, abnormal tongue morphology, abnormal mandibular coronoid process morphology, abnormal tongue muscle morphology, decreased tongue size, abnormal extrinsic tongue muscle morphology, small mandible, abnormal mandibular angle morphology, small Meckel's cartilage Allele Detail: Transgenic, Targeted

  • From Current Category

Cite this (MGI Cat# 5570667, RRID:MGI:5570667)

Source Database: MGI, catalog # 5570667
Genetic Background: involves: C57BL/6 * C57BL/6NCrlj * CBA/JNCrlj
Affected Genes: Runx2
Genomic Alteration: Tg(Col2a1-cre)1Star; tm1.1Yyon
Availability: Availability unknown check source stock center
Reference: PMID:23553905
Notes: neonatal lethality, complete penetrance, respiratory distress, delayed bone ossification, delayed endochondral bone ossification Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2674287, RRID:MGI:2674287)

Source Database: MGI, catalog # 2674287
Genetic Background: involves: 129P2/OlaHsd * C3H/HeJ * C57BL/6
Affected Genes: Meox2, Meox1
Genomic Alteration: Tg(Mx1-TAX)2627Arnh; tm1Vpa
Availability: Availability unknown check source stock center
Reference: PMID:12925591
Notes: decreased body length, absent ribs, abnormal skeletal muscle morphology, neonatal lethality, complete penetrance, vestigial tail, abnormal somite development, absent vertebrae Allele Detail: Targeted, Transgenic

  • From Current Category

Cite this (MGI Cat# 3722059, RRID:MGI:3722059)

Source Database: MGI, catalog # 3722059
Genetic Background: C3HeB/FeJ-Dync1h1
Affected Genes: Dync1h1
Genomic Alteration: Cra1
Availability: Availability unknown check source stock center
Reference: PMID:12730604
Notes: neuronal intranuclear inclusions, neonatal lethality, complete penetrance, decreased spinal cord ventral horn cell number, aphagia, paralysis Allele Detail: Chemically induced (ENU)

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