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on page 1 showing 20 out of 1,139 results

Cite this (MGI Cat# 2656901, RRID:MGI:2656901)

Source Database: MGI, catalog # 2656901
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Affected Genes: Kif5a
Genomic Alteration: tm1Gsn
Availability: Availability unknown check source stock center
Reference: PMID:12682084
Notes: nervous system phenotype, abnormal breathing pattern, neonatal lethality, complete penetrance, cyanosis, atelectasis, abnormal motor neuron morphology Allele Detail: Targeted

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Cite this (MGI Cat# 2674285, RRID:MGI:2674285)

Source Database: MGI, catalog # 2674285
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Meox1, Meox2
Genomic Alteration: tm1Vpa; tm1Bmk
Availability: Availability unknown check source stock center
Reference: PMID:12925591
Notes: absent ribs, abnormal myotome development, decreased brown adipose tissue amount, fused dorsal root ganglion, abnormal dorsal root ganglion morphology, loose skin, abnormal vertebral column morphology, abnormal vertebrae morphology, abnormal sternum morphology, abnormal spinal nerve morphology, abnormal somite size, abnormal sclerotome morphology, abnormal somite shape, abnormal axial skeleton morphology, abnormal dermomyotome development, abnormal epaxial muscle morphology, occipital bone hypoplasia, abnormal somite development, cyanosis, vestigial tail, neonatal lethality, complete penetrance, abnormal skeletal muscle morphology, abnormal hypaxial muscle morphology, decreased body length, absent caudal vertebrae, abnormal dorsal-ventral polarity of the somites Allele Detail: Targeted

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Cite this (MGI Cat# 5440186, RRID:MGI:5440186)

Source Database: MGI, catalog # 5440186
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Ctnnb1
Genomic Alteration: Tg(Foxn1-cre)1Tbo; tm2Kem; tm2.1Kem
Availability: Availability unknown check source stock center
Reference: PMID:22991437
Notes: neonatal lethality, complete penetrance, skin lesions Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3044767, RRID:MGI:3044767)

Source Database: MGI, catalog # 3044767
Genetic Background: B6.129S2-Spi1
Affected Genes: Spi1
Genomic Alteration: tm1Kast
Availability: Availability unknown check source stock center
Reference: PMID:14739214
Notes: absent B cells, failure of myelopoiesis, neonatal lethality, complete penetrance, abnormal fetal derived definitive erythrocyte cell number, abnormal erythropoiesis Allele Detail: Targeted

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Cite this (MGI Cat# 3708884, RRID:MGI:3708884)

Source Database: MGI, catalog # 3708884
Genetic Background: involves: C57BL/6
Affected Genes: Lrp4
Genomic Alteration: mte
Availability: Availability unknown check source stock center
Reference: PMID:17119023
Notes: abnormal phrenic nerve morphology, small lung, abnormal mammary gland bud morphology, abnormal vibrissa morphology, single kidney, failure of neuromuscular synapse presynaptic differentiation, syndactyly, failure of neuromuscular synapse postsynaptic differentiation, abnormal tooth development, abnormal apical ectodermal ridge morphology, abnormal autopod morphology, abnormal neuromuscular synapse morphology, abnormal hair follicle development, abnormal digit morphology, oligodactyly, ectopic digits, cyanosis, atelectasis, no spontaneous movement, respiratory failure, neonatal lethality, complete penetrance, fused metatarsal bones, fused metacarpal bones, absent kidney Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 2167059, RRID:MGI:2167059)

Source Database: MGI, catalog # 2167059
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Affected Genes: Prrx1, Prrx2
Genomic Alteration: tm1Mjk; tm1Tex
Availability: Availability unknown check source stock center
Reference: PMID:9876178, PMID:9882503
Notes: abnormal tooth development, abnormal bone ossification, abnormal long bone hypertrophic chondrocyte zone, abnormal epiphyseal plate morphology, syndactyly, absent triquetrum, postaxial polydactyly, preaxial polydactyly, abnormal autopod morphology, abnormal ameloblast differentiation, respiratory failure, abnormal apical ectodermal ridge morphology, oligodactyly, abnormal digit morphology, neonatal lethality, complete penetrance, abnormal carpal bone morphology, absent maxillary zygomatic process, absent incisors, growth retardation of incisors, abnormal mandible morphology, absent maxillary shelf, absent Meckel's cartilage, abnormal ear position, abnormal limb morphology, cyanosis, aphagia, abnormal hindlimb zeugopod morphology, abnormal phalanx morphology, ectopic digits, outer ear hypoplasia, short mandible, eyelids open at birth, neonatal lethality, complete penetrance, absent eyelids, abnormal odontoblast differentiation, cleft secondary palate, respiratory distress Allele Detail: Targeted

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Cite this (MGI Cat# 2673173, RRID:MGI:2673173)

Source Database: MGI, catalog # 2673173
Genetic Background: 129S/SvEv-Hoxb4
Affected Genes: Hoxb4
Genomic Alteration: tm1Bay
Availability: Availability unknown check source stock center
Reference: PMID:8097432
Notes: abnormal cervical axis morphology, abnormal sternebra morphology, cervical vertebral transformation, neonatal lethality, complete penetrance, split sternum Allele Detail: Targeted

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Cite this (MGI Cat# 2663068, RRID:MGI:2663068)

Source Database: MGI, catalog # 2663068
Genetic Background: involves: 129P2/OlaHsd
Affected Genes: Dach1
Genomic Alteration: tm1Krs
Availability: Availability unknown check source stock center
Reference: PMID:12508235, PMID:20869363
Notes: neonatal lethality, complete penetrance, absent gastric milk in neonates, respiratory distress, decreased pancreatic alpha cell number, small pancreatic islets, decreased pancreatic beta cell number, decreased pancreatic beta cell proliferation, endocrine/exocrine gland phenotype, cyanosis, nervous system phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 2662384, RRID:MGI:2662384)

Source Database: MGI, catalog # 2662384
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Sp3
Genomic Alteration: tm1Sus
Availability: Availability unknown check source stock center
Reference: PMID:17584888, PMID:10675334, PMID:11472836, PMID:12676787
Notes: abnormal osteoblast differentiation, abnormal ameloblast morphology, abnormal tooth development, abnormal enamel development, decreased birth body size, abnormal pulmonary alveolus morphology, abnormal dentin development, neonatal lethality, complete penetrance, respiratory failure, abnormal bone mineralization, abnormal phalanx morphology, abnormal cranium morphology, abnormal metatarsal bone morphology, abnormal metacarpal bone morphology, abnormal cervical atlas morphology, abnormal xiphoid process morphology, abnormal trophoblast glycogen cell morphology, abnormal spongiotrophoblast cell morphology, abnormal vertebral body morphology, abnormal supraoccipital bone morphology, abnormal presphenoid bone morphology, abnormal parietal bone morphology, abnormal nasal bone morphology, abnormal interparietal bone morphology, delayed bone ossification, abnormal frontal bone morphology, abnormal basicranium morphology, abnormal basisphenoid bone morphology, abnormal sternum ossification, delayed intramembranous bone ossification, delayed endochondral bone ossification, abnormal sagittal suture morphology, small thymus, decreased CD4-positive, alpha beta T cell number, abnormal B cell differentiation, abnormal erythropoiesis, abnormal placenta labyrinth morphology, decreased spongiotrophoblast size, liver hypoplasia Allele Detail: Targeted

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Cite this (MGI Cat# 3606230, RRID:MGI:3606230)

Source Database: MGI, catalog # 3606230
Genetic Background: involves: 129S6/SvEvTac * C3H * C57BL/6
Affected Genes: Fgfr1
Genomic Alteration: tm3.2Cxd; Tg(T-cre)1Lwd
Availability: Availability unknown check source stock center
Reference: PMID:16120640
Notes: abnormal hindlimb morphology, abnormal axial skeleton morphology, abnormal forelimb stylopod morphology, abnormal cartilage development, oligodactyly, neonatal lethality, complete penetrance, abnormal forelimb zeugopod morphology, abnormal somite size, abnormal apical ectodermal ridge morphology, abnormal forelimb bud morphology, abnormal neural plate morphology Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 2654618, RRID:MGI:2654618)

Source Database: MGI, catalog # 2654618
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J
Affected Genes: Pitx2
Genomic Alteration: tm3.1Jfm
Availability: Availability unknown check source stock center
Reference: PMID:12397115
Notes: abnormal pharyngeal arch artery morphology, anomalous pulmonary venous connection, cyanosis, double outlet right ventricle, abnormal atrioventricular cushion morphology, ventricular septal defect, abnormal left-right axis patterning, abnormal vein morphology, double aortic arch, right aortic arch, embryo phenotype, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 4410313, RRID:MGI:4410313)

Source Database: MGI, catalog # 4410313
Genetic Background: involves: C57BL/6
Affected Genes: Efemp2
Genomic Alteration: tm1.2Tynk
Availability: Availability unknown check source stock center
Reference: PMID:19855011
Notes: neonatal lethality, complete penetrance, abnormal aorta elastic tissue morphology, abnormal aorta morphology, diaphragmatic hernia Allele Detail: Targeted

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Cite this (MGI Cat# 3764932, RRID:MGI:3764932)

Source Database: MGI, catalog # 3764932
Genetic Background: involves: 129S2/SvPas
Affected Genes: Cyp26b1
Genomic Alteration: tm1.1Ptk
Availability: Availability unknown check source stock center
Reference: PMID:17584971
Notes: abnormal craniofacial morphology, decreased male germ cell number, respiratory distress, neonatal lethality, complete penetrance, abnormal male germ cell apoptosis, small testis, abnormal limb morphology Allele Detail: Targeted

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Cite this (MGI Cat# 3702521, RRID:MGI:3702521)

Source Database: MGI, catalog # 3702521
Genetic Background: involves: 129 * CD-1
Affected Genes: Gsk3b
Genomic Alteration: tm1Jrw
Availability: Availability unknown check source stock center
Reference: PMID:17293880
Notes: split sternum, cleft secondary palate, abnormal sternum ossification, xiphoid process foramen, delayed bone ossification, neonatal lethality, complete penetrance, palatal shelves fail to meet at midline Allele Detail: Targeted

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Cite this (MGI Cat# 3722060, RRID:MGI:3722060)

Source Database: MGI, catalog # 3722060
Genetic Background: C3H/HeH-Dync1h1
Affected Genes: Dync1h1
Genomic Alteration: Loa
Availability: Availability unknown check source stock center
Reference: PMID:12730604
Notes: neuronal intranuclear inclusions, decreased spinal cord ventral horn cell number, absent suckling reflex, abnormal axonal transport, abnormal motor neuron innervation pattern, neonatal lethality, complete penetrance, aphagia, paralysis Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 3609425, RRID:MGI:3609425)

Source Database: MGI, catalog # 3609425
Genetic Background: involves: 129P2/OlaHsd
Affected Genes: Chuk
Genomic Alteration: tm1Aki
Availability: Availability unknown check source stock center
Reference: PMID:10195895
Notes: short tail, shortened head, small cranium, thick epidermis, abnormal craniofacial bone morphology, tight skin, cellular phenotype, abnormal epidermis stratum corneum morphology, abnormal epidermis stratum basale morphology, impaired skin barrier function, absent epidermis stratum granulosum, abnormal hair follicle development, abnormal keratinocyte differentiation, abnormal limb bud morphology, abnormal limb morphology, abnormal epidermis stratum spinosum morphology, abnormal epidermis suprabasal layer morphology, epidermal hyperplasia, neonatal lethality, complete penetrance, parakeratosis, shiny skin, short limbs, short snout Allele Detail: Targeted

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Cite this (MGI Cat# 3767808, RRID:MGI:3767808)

Source Database: MGI, catalog # 3767808
Genetic Background: Not Specified
Affected Genes: Isl2
Genomic Alteration: tm3.1(Mnx1-Lhx3)Slp
Availability: Availability unknown check source stock center
Reference: PMID:10952312, PMID:16772167
Notes: abnormal axon morphology, abnormal motor neuron innervation pattern, respiratory failure, abnormal motor neuron morphology, abnormal axon morphology, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 5707211, RRID:MGI:5707211)

Source Database: MGI, catalog # 5707211
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6J * C57BL/6N
Affected Genes: Spag17
Genomic Alteration: tm1d(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:23418344
Notes: hydroencephaly, pulmonary edema, impaired mucociliary clearance, immotile respiratory cilia, abnormal suckling behavior, growth/size/body region phenotype, absent gastric milk in neonates, abnormal respiratory motile cilium morphology, respiratory failure, enlarged lateral ventricles, abnormal respiratory motile cilium physiology, neonatal lethality, complete penetrance, hypoactivity, respiratory distress, abnormal pulmonary alveolus epithelium morphology, cyanosis, enlarged brain ventricles, decreased heart rate, atelectasis Allele Detail: Targeted

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Cite this (MGI Cat# 3819846, RRID:MGI:3819846)

Source Database: MGI, catalog # 3819846
Genetic Background: involves: C57BL/6
Affected Genes: Nalcn
Genomic Alteration: tm1.1Dren
Availability: Availability unknown check source stock center
Reference: PMID:17448995
Notes: apnea, abnormal nerve conduction, decreased physiological sensitivity to xenobiotic, abnormal nervous system electrophysiology, abnormal breathing pattern, embryo phenotype, abnormal channel response, behavior/neurological phenotype, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 6195291, RRID:MGI:6195291)

Source Database: MGI, catalog # 6195291
Genetic Background: involves: CD-1
Affected Genes: Ifitm5
Genomic Alteration: em1Pmof
Availability: Availability unknown check source stock center
Reference: PMID:29174564
Notes: decreased bone mineralization, abnormal bone marrow cavity morphology, abnormal bone ossification, abnormal compact bone morphology, abnormal intramembranous bone ossification, impaired osteoblast differentiation, disorganized long bone epiphyseal plate, abnormal limb morphology, abnormal long bone diaphysis morphology, short mandible, abnormal neurocranium morphology, abnormal osteoblast physiology, abnormal osteoclast morphology, short limbs, neonatal lethality, complete penetrance, mandible hypoplasia, abnormal rib morphology, increased width of hypertrophic chondrocyte zone, abnormal thoracic cage morphology, abnormal trabecular bone morphology, absent compact bone, bowed radius, bowed tibia, bowed ulna, clavicle hypoplasia, decreased alkaline phosphatase activity Allele Detail: Endonuclease-mediated

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