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on page 1 showing 20 out of 2,966 results

Cite this (MGI Cat# 5781561, RRID:MGI:5781561)

Source Database: MGI, catalog # 5781561
Genetic Background: B6JTyr;B6N-Agtr2/Wtsi
Affected Genes: Agtr2
Genomic Alteration: tm1a(EUCOMM)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: decreased body weight, decreased circulating LDL cholesterol level, decreased circulating alanine transaminase level Allele Detail: Targeted

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Cite this (MGI Cat# 4358789, RRID:MGI:4358789)

Source Database: MGI, catalog # 4358789
Genetic Background: involves: 129S4/SvJae * C57BL/6
Affected Genes: Pla2g4a
Genomic Alteration: tm1Jvb
Availability: Availability unknown check source stock center
Reference: PMID:11249852
Notes: increased blood osmolality, abnormal response/metabolism to endogenous compounds, decreased urine osmolality, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 3619044, RRID:MGI:3619044)

Source Database: MGI, catalog # 3619044
Genetic Background: B6.Cg-Lep Mapk8
Affected Genes: Lep, Mapk8
Genomic Alteration: tm1Wag; ob
Availability: Availability unknown check source stock center
Reference: PMID:12447443
Notes: decreased circulating glucose level, decreased circulating insulin level, decreased body weight Allele Detail: Spontaneous, Targeted

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Cite this (MGI Cat# 3811816, RRID:MGI:3811816)

Source Database: MGI, catalog # 3811816
Genetic Background: involves: 129P2/OlaHsd * FVB/N
Affected Genes: Myc
Genomic Alteration: tm1Atp
Availability: Availability unknown check source stock center
Reference: PMID:11742404
Notes: spleen hypoplasia, decreased white adipose tissue amount, decreased T cell proliferation, lymphoid hypoplasia, lymph node hypoplasia, decreased body size, small lymphoid organs, postnatal growth retardation, decreased fetal size, decreased bone marrow cell number, decreased fibroblast proliferation, short tail, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 3050469, RRID:MGI:3050469)

Source Database: MGI, catalog # 3050469
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Affected Genes: Ptpn11
Genomic Alteration: tm1Bgn
Availability: Availability unknown check source stock center
Reference: PMID:15273746
Notes: enlarged spleen, increased leukocyte cell number, myeloid hyperplasia, small cranium, increased cell proliferation, decreased body weight, decreased cardiomyocyte apoptosis, abnormal heart development, decreased body length, flattened snout, broad snout, enlarged mitral valve, double outlet right ventricle, hepatic necrosis, increased neutrophil cell number, perinatal lethality, incomplete penetrance, increased lymphocyte cell number, ventricular septal defect Allele Detail: Targeted

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Cite this (MGI Cat# 5806513, RRID:MGI:5806513)

Source Database: MGI, catalog # 5806513
Genetic Background: C57BL/6J-Kbtbd2
Affected Genes: Kbtbd2
Genomic Alteration: m1Btlr
Availability: Availability unknown check source stock center
Reference: PMID:27708159
Notes: increased circulating alanine transaminase level, homeostasis/metabolism phenotype, increased circulating aspartate transaminase level, increased circulating insulin level, increased fasted circulating glucose level, increased lean body mass, increased liver triglyceride level, increased liver weight, insulin resistance, male infertility, pale liver, postnatal growth retardation, abnormal white adipose tissue physiology, decreased adiponectin level, decreased body size, enlarged liver, decreased inguinal fat pad weight, decreased epididymal fat pad weight, decreased circulating leptin level, decreased body weight, female infertility, hepatic steatosis Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 4889117, RRID:MGI:4889117)

Source Database: MGI, catalog # 4889117
Genetic Background: B6.Cg-Lep Akt2
Affected Genes: Akt2, Lep
Genomic Alteration: tm1.1Mbb; ob
Availability: Availability unknown check source stock center
Reference: PMID:19883618
Notes: increased circulating insulin level, abnormal lipid homeostasis, decreased liver weight, decreased body weight, increased circulating glucose level, decreased liver triglyceride level, decreased circulating cholesterol level Allele Detail: Spontaneous, Targeted

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Cite this (MGI Cat# 5782069, RRID:MGI:5782069)

Source Database: MGI, catalog # 5782069
Genetic Background: C57BL/6N-Elk4/H
Affected Genes: Elk4
Genomic Alteration: tm1a(EUCOMM)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: decreased mature B cell number, decreased body weight, corneal opacity, decreased circulating HDL cholesterol level, increased circulating alkaline phosphatase level, abnormal cornea morphology, decreased lean body mass, increased B cell number, decreased circulating cholesterol level, increased T cell number, decreased circulating serum albumin level, abnormal retina morphology, decreased T cell number, abnormal bone structure, decreased bone mineral density, increased lactate dehydrogenase level, abnormal tail movements, decreased circulating triglyceride level, decreased CD8-positive, alpha-beta T cell number, decreased CD4-positive, alpha beta T cell number, abnormal bone mineralization, decreased circulating total protein level Allele Detail: Targeted

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Cite this (MGI Cat# 3497709, RRID:MGI:3497709)

Source Database: MGI, catalog # 3497709
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
Affected Genes: Neurod1
Genomic Alteration: Tg(RIP1-Neurod1)1Jle; tm1Jle
Availability: Availability unknown check source stock center
Reference: PMID:10398678, PMID:11152640
Notes: decreased Purkinje cell number, absent endocochlear potential, decreased body weight, postnatal growth retardation, abnormal motor coordination/balance, abnormal cerebellar foliation, abnormal neuron differentiation, abnormal Purkinje cell morphology, abnormal vestibulocochlear ganglion morphology, abnormal sensory neuron innervation pattern, reduced modiolus, abnormal vestibular ganglion morphology, abnormal cochlear sensory epithelium morphology, hearing/vestibular/ear phenotype, absent dentate gyrus, thin external granule cell layer, absent cochlear ganglion, impaired balance, small cerebellum, abnormal cerebellar granule layer morphology, ataxia, decreased sensory neuron number, deafness Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3783638, RRID:MGI:3783638)

Source Database: MGI, catalog # 3783638
Genetic Background: involves: 129P1/Re
Affected Genes: Lama2
Genomic Alteration: dy
Availability: Availability unknown check source stock center
Reference: PMID:16589799
Notes: abnormal skeletal muscle fiber morphology, progressive muscle weakness, increased variability of skeletal muscle fiber size, dystrophic muscle, kyphosis, paresis, ataxia, cachexia, premature death, centrally nucleated skeletal muscle fibers, abnormal sexual interaction, abnormal sarcolemma morphology, decreased body weight Allele Detail: Spontaneous

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Cite this (MGI Cat# 5902185, RRID:MGI:5902185)

Source Database: MGI, catalog # 5902185
Genetic Background: C57BL/6N-Gif
Affected Genes: Gif
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:27329747
Notes: abnormal hepatocyte morphology, increased CD4-positive, alpha beta T cell number, increased T cell number, decreased circulating cholesterol level, decreased body weight, abnormal circulating lipoprotein level, increased susceptibility to bacterial infection induced morbidity/mortality, decreased circulating glucose level, increased blood urea nitrogen level, decreased circulating glycerol level, decreased circulating iron level, decreased circulating serum albumin level, decreased erythrocyte cell number, extramedullary hematopoiesis, abnormal megakaryocyte morphology, abnormal vitamin B12 level, increased susceptibility to bacterial infection, increased mean corpuscular volume, maternal effect Allele Detail: Targeted

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Cite this (MGI Cat# 2663265, RRID:MGI:2663265)

Source Database: MGI, catalog # 2663265
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Prkaca
Genomic Alteration: tm1Gsm
Availability: Availability unknown check source stock center
Reference: PMID:11875122, PMID:11886853
Notes: postnatal growth retardation, reproductive system phenotype, asthenozoospermia, postnatal lethality, incomplete penetrance, postnatal growth retardation, decreased urine protein level, male infertility, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 3043097, RRID:MGI:3043097)

Source Database: MGI, catalog # 3043097
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Kcna3
Genomic Alteration: tm1Gvd
Availability: Availability unknown check source stock center
Reference: PMID:12588802, PMID:14981264
Notes: increased muscle cell glucose uptake, increased insulin sensitivity, decreased circulating insulin level, increased basal metabolism, decreased susceptibility to diet-induced obesity, decreased body weight, abnormal glucose homeostasis Allele Detail: Targeted

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Cite this (MGI Cat# 3605109, RRID:MGI:3605109)

Source Database: MGI, catalog # 3605109
Genetic Background: involves: DBA/2 * DU6i
Affected Genes: Bodw4, Bodw3
Genomic Alteration: DBA/2; DU6i
Availability: Availability unknown check source stock center
Reference: PMID:16151693
Notes: decreased body weight Allele Detail: QTL

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Cite this (MGI Cat# 3818682, RRID:MGI:3818682)

Source Database: MGI, catalog # 3818682
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Rhcg
Genomic Alteration: tm1Ibmm
Availability: Availability unknown check source stock center
Reference: PMID:19020613
Notes: renal tubular acidosis, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 3761138, RRID:MGI:3761138)

Source Database: MGI, catalog # 3761138
Genetic Background: B6.129P2-Hrh1
Affected Genes: Hrh1
Genomic Alteration: tm1Wtn
Availability: Availability unknown check source stock center
Reference: PMID:16680192, PMID:15331534
Notes: increased triglyceride level, increased white adipose tissue amount, decreased body weight, decreased circulating insulin level, increased fat cell size, decreased food intake, increased body weight, increased circulating free fatty acid level, decreased total body fat amount, abnormal response/metabolism to endogenous compounds, increased liver triglyceride level, increased IgG level, decreased interferon-gamma secretion, increased IgM level, increased food intake, abnormal circadian feeding behavior, increased brown adipose tissue amount, decreased interleukin-5 secretion, decreased inflammatory response, decreased interleukin-13 secretion, increased circulating leptin level Allele Detail: Targeted

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Cite this (RGD Cat# 61010, RRID:RGD_61010)

Source Database: RGD, catalog # 61010
Genetic Background: inbred strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:8696337
Notes: abnormal cardiac stroke volume, decreased body weight, hypertension, increased systemic arterial blood pressure The A1-sb and A3 substrains of SHR which had been bred as parallel lines from F20 to F36 were crossed (?) and further inbred with selection of offspring of parents that died of stroke (Okamoto et al 1974, 1986, Yamori 1984). To NIH in 1976, and designated SHRSP/A3N. Pathophysiology reviewed by Volpe and Rabbatu (1994). Iffa Credo, L'arbresle, France, Max-Delbruck-Center for Molecular Medicine, Berlin-Buch

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Cite this (MGI Cat# 5691569, RRID:MGI:5691569)

Source Database: MGI, catalog # 5691569
Genetic Background: Not Specified
Affected Genes: Pacsin1
Genomic Alteration: tm1.1Bqu
Availability: Availability unknown check source stock center
Reference: PMID:21926968
Notes: abnormal inhibitory postsynaptic currents, decreased body weight, abnormal vesicle-mediated transport, decreased synaptic depression, abnormal miniature inhibitory postsynaptic currents, abnormal retinal outer plexiform layer morphology, increased hippocampus volume, mortality/aging, abnormal synapse morphology, abnormal synaptic vesicle morphology, abnormal synaptic vesicle number, abnormal synaptic vesicle recycling, decreased excitatory postsynaptic current amplitude, tonic-clonic seizures, abnormal miniature excitatory postsynaptic currents, reduced fertility, abnormal nervous system electrophysiology Allele Detail: Targeted

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Cite this (MGI Cat# 3716903, RRID:MGI:3716903)

Source Database: MGI, catalog # 3716903
Genetic Background: C3HeB/FeJ-Mhdawbs1/Ieg
Affected Genes:
Genomic Alteration: Mhdawbs1
Availability: Availability unknown check source stock center
Reference:
Notes: decreased body weight, kinked tail, belly spot Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 3623123, RRID:MGI:3623123)

Source Database: MGI, catalog # 3623123
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Drd2
Genomic Alteration: tm1Schm
Availability: Availability unknown check source stock center
Reference: PMID:10391470
Notes: decreased body size, abnormal dopamine level, abnormal locomotor behavior, bradykinesia, decreased body weight, hunched posture, premature death Allele Detail: Targeted

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