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on page 1 showing 20 out of 2,925 results

Cite this (MGI Cat# 4361581, RRID:MGI:4361581)

Source Database: MGI, catalog # 4361581
Genetic Background: CBA/H
Affected Genes:
Genomic Alteration: fm
Availability: Availability unknown check source stock center
Reference:
Notes: hypoactivity, weight loss, abnormal lymph node morphology, abnormal neuron morphology, abnormal Peyer's patch morphology, foam cell reticulosis, decreased body weight, abnormal spleen morphology, abnormal liver morphology, premature death, abnormal thymus morphology Allele Detail: Spontaneous

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Cite this (MGI Cat# 3609490, RRID:MGI:3609490)

Source Database: MGI, catalog # 3609490
Genetic Background: involves: C57BL/6J * M. m. castaneus
Affected Genes: Pbwg22
Genomic Alteration: M. m. castaneus
Availability: Availability unknown check source stock center
Reference: PMID:16174331
Notes: decreased body weight Allele Detail: QTL

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Cite this (MGI Cat# 4366906, RRID:MGI:4366906)

Source Database: MGI, catalog # 4366906
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Gigyf2
Genomic Alteration: Gt(XH076)Byg
Availability: Availability unknown check source stock center
Reference: PMID:19744960
Notes: decreased body length, decreased body weight, postnatal lethality, incomplete penetrance, neonatal lethality, incomplete penetrance, abnormal food intake Allele Detail: Gene trapped

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Cite this (MGI Cat# 2175179, RRID:MGI:2175179)

Source Database: MGI, catalog # 2175179
Genetic Background: involves: 129S1/Sv
Affected Genes: Ntf3
Genomic Alteration: tm1Par
Availability: Availability unknown check source stock center
Reference: PMID:9364058, PMID:8841198, PMID:10681461, PMID:7991545, PMID:19755105
Notes: enlarged heart, small trigeminal ganglion, small dorsal root ganglion, decreased sensory neuron number, perinatal lethality, incomplete penetrance, cardiac hypertrophy, decreased heart rate, dilated heart right ventricle, small L4 dorsal root ganglion, small geniculate ganglion, small nodose ganglion, small petrosal ganglion, small trigeminal ganglion, abnormal somatic nervous system morphology, perinatal lethality, incomplete penetrance, decreased body weight, abnormal motor capabilities/coordination/movement, decreased spinal cord size, postnatal lethality, complete penetrance, abnormal blood vessel morphology, abnormal heart morphology, abnormal proprioceptive neuron morphology, abnormal posture, abnormal semilunar valve morphology, abnormal atrioventricular valve morphology, abnormal heart development, abnormal pulmonary vein morphology, dilated pulmonary artery, abnormal heart ventricle outflow tract morphology, abnormal atrium myocardial trabeculae morphology, thick mitral valve cusps, abnormal heart left ventricle size, sinus venosus hypoplasia, pulmonary alveolar hemorrhage, abnormal heart ventricle morphology, overriding aortic valve, persistent truncus arteriosis, pulmonary edema, pulmonary valve stenosis, atrium myocardium hypoplasia, vascular smooth muscle hypotrophy, perimembraneous ventricular septal defect, abnormal cardiovascular system morphology, abnormal heart valve morphology, abnormal sinus venosus morphology, aneurysm, ostium secundum atrial septal defect, premature closure of the ductus arteriosus, thick aortic valve cusps, heart right ventricle outflow tract stenosis, dilated heart atrium, abnormal dorsal root ganglion morphology, decreased sensory neuron number Allele Detail: Targeted

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Cite this (MGI Cat# 5513111, RRID:MGI:5513111)

Source Database: MGI, catalog # 5513111
Genetic Background: involves: 129S1/Sv * C57BL/6J
Affected Genes: Mnx1, Tardbp
Genomic Alteration: tm1.2Cjks; tm1.1Ckjs; tm4(cre)Tmj
Availability: Availability unknown check source stock center
Reference: PMID:22718760
Notes: astrocytosis, abnormal spinal cord ventral horn morphology, limb grasping, impaired coordination, muscle weakness, kyphosis, weight loss, premature death, muscular atrophy, motor neuron degeneration, increased microglial cell activation, decreased body weight, abnormal motor neuron morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5445419, RRID:MGI:5445419)

Source Database: MGI, catalog # 5445419
Genetic Background: involves: 129P2/OlaHsd * FVB/N
Affected Genes: Cftr
Genomic Alteration: tm1Eur
Availability: Availability unknown check source stock center
Reference: PMID:7556083
Notes: abnormal gallbladder physiology, decreased body weight, abnormal intestinal goblet cell morphology, decreased intestinal epithelial chloride transmembrane transport, abnormal large intestine crypts of Lieberkuhn morphology, postnatal growth retardation, decreased respiratory epithelial chloride transmembrane transport Allele Detail: Targeted

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Cite this (MGI Cat# 3775301, RRID:MGI:3775301)

Source Database: MGI, catalog # 3775301
Genetic Background: involves: 129/Sv * C57BL/6 * FVB/N
Affected Genes: Igf1r
Genomic Alteration: tm1.2Mhz
Availability: Availability unknown check source stock center
Reference: PMID:10875258
Notes: respiratory failure, neonatal lethality, complete penetrance, decreased body weight, abnormal muscle morphology Allele Detail: Targeted

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Cite this (MGI Cat# 3029166, RRID:MGI:3029166)

Source Database: MGI, catalog # 3029166
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Grb14
Genomic Alteration: tm1Daly
Availability: Availability unknown check source stock center
Reference: PMID:14749734
Notes: increased heart weight, increased insulin sensitivity, decreased liver weight, improved glucose tolerance, decreased body weight, decreased spleen weight Allele Detail: Targeted

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Cite this (MGI Cat# 3723215, RRID:MGI:3723215)

Source Database: MGI, catalog # 3723215
Genetic Background: involves: DBA/2OlaHsd * NMRI8/Fbn
Affected Genes: Mtbcq5
Genomic Alteration: NMRI8/Fbn
Availability: Availability unknown check source stock center
Reference: PMID:17517159
Notes: decreased body weight Allele Detail: QTL

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Cite this (MGI Cat# 3040259, RRID:MGI:3040259)

Source Database: MGI, catalog # 3040259
Genetic Background: involves: C57BL/6J * M. m. castaneus
Affected Genes: Pbwg6
Genomic Alteration: M. m. castaneus
Availability: Availability unknown check source stock center
Reference: PMID:16174331, PMID:15056934
Notes: decreased body weight, postnatal growth retardation Allele Detail: QTL

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Cite this (MGI Cat# 4840214, RRID:MGI:4840214)

Source Database: MGI, catalog # 4840214
Genetic Background: involves: 129S4/SvJaeSor * 129S6/SvEvTac
Affected Genes: Myf5, Stat5a, Stat5b
Genomic Alteration: tm3(cre)Sor; tm2Mam; tm1Mam
Availability: Availability unknown check source stock center
Reference: PMID:17158201
Notes: decreased body length, impaired glucose tolerance, increased circulating triglyceride level, increased total body fat amount, decreased circulating insulin-like growth factor I level, decreased body weight, decreased lean body mass Allele Detail: Targeted

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Cite this (RGD Cat# 10045593, RRID:RGD_10045593)

Source Database: RGD, catalog # 10045593
Genetic Background: mutant strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:25005781
Notes: Duchenne muscular dystrophy, centrally nucleated skeletal muscle fibers, decreased body weight, decreased skeletal muscle fiber diameter, increased creatine kinase level, increased heart weight, increased tibialis anterior weight, muscle degeneration By CRISPR/Cas9 system, mutation was introduced in dystrophin (Dmd) gene of Wistar-Imamichi rat. The resulting mutation is a 329-bp deletion around exon 3 and 2-bp substitution in exon16. National BioResource Project for the Rat in Japan

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Cite this (MGI Cat# 3045764, RRID:MGI:3045764)

Source Database: MGI, catalog # 3045764
Genetic Background: involves: B6.129P2-Lipc/J * SPRET/EiJ
Affected Genes: Bsbob
Genomic Alteration: C57BL/6J; SPRET/EiJ
Availability: Availability unknown check source stock center
Reference: PMID:15181537, PMID:15166164
Notes: decreased gonadal fat pad weight, decreased percent body fat/body weight, decreased total body fat amount, decreased retroperitoneal fat pad weight, decreased body weight, decreased total body fat amount, decreased white adipose tissue amount Allele Detail: QTL

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Cite this (MGI Cat# 6113593, RRID:MGI:6113593)

Source Database: MGI, catalog # 6113593
Genetic Background: C57BL/6J-Pappa2
Affected Genes: Pappa2
Genomic Alteration: m3Btlr
Availability: Availability unknown check source stock center
Reference:
Notes: decreased body weight Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 3505857, RRID:MGI:3505857)

Source Database: MGI, catalog # 3505857
Genetic Background: involves: 129/Sv * C57BL/6
Affected Genes: C3
Genomic Alteration: tm1Hrc
Availability: Availability unknown check source stock center
Reference: PMID:10698180, PMID:10593909
Notes: increased circulating free fatty acid level, decreased body weight, decreased total body fat amount, decreased white adipose tissue amount, abnormal glucose homeostasis, abnormal energy expenditure, abnormal energy expenditure, abnormal lipid homeostasis, abnormal glucose homeostasis, decreased circulating glucose level, decreased circulating leptin level, polyphagia, decreased circulating triglyceride level, decreased total body fat amount, decreased circulating insulin level, increased triglyceride level, abnormal lipid homeostasis, increased circulating free fatty acid level, polyphagia, increased brown adipose tissue amount, decreased circulating leptin level, decreased circulating glucose level Allele Detail: Targeted

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Cite this (MGI Cat# 2664581, RRID:MGI:2664581)

Source Database: MGI, catalog # 2664581
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Affected Genes: Esr1
Genomic Alteration: tm1Ksk
Availability: Availability unknown check source stock center
Reference: PMID:11014235, PMID:8248223, PMID:11380688, PMID:8895349, PMID:8584021, PMID:11095962, PMID:14745006, PMID:9832446, PMID:15283680, PMID:10805804, PMID:9391155, PMID:9037078, PMID:10558910, PMID:11114183, PMID:11311804, PMID:12603601
Notes: short tibia, increased spleen germinal center number, abnormal lymph node cell ratio, glomerulonephritis, cortical renal glomerulopathies, abnormal spleen physiology, increased IgG3 level, renal glomerular immunoglobulin deposits, increased anti-double stranded DNA antibody level, increased urine protein level, increased plasma cell number, abnormal kidney physiology, failure of ejaculation, decreased aggression towards males, decreased bone mineral content, short femur, decreased circulating insulin-like growth factor I level, abnormal circulating protein level, decreased compact bone area, decreased body weight, decreased bone mineral density, decreased bone strength, decreased lung weight, decreased heart weight, increased circulating cholesterol level, insulin resistance, increased circulating leptin level, increased gonadal fat pad weight, increased retroperitoneal fat pad weight, increased total body fat amount, obese, increased circulating HDL cholesterol level, decreased CD8-positive, alpha-beta T cell number, thymus hypoplasia, increased double-positive T cell number, decreased CD4-positive, alpha beta T cell number, absent corpus luteum, oligozoospermia, increased vertical activity, failure of ejaculation, reduced male mating frequency, decreased aggression, hyperactivity, abnormal female reproductive system physiology, reduced male fertility, abnormal hypothalamus morphology, abnormal ovary morphology, uterus hypoplasia, decreased testis weight, abnormal seminiferous tubule epithelium morphology, dilated seminiferous tubules, abnormal epididymis morphology, increased circulating testosterone level, decreased testis weight, dilated rete testis, abnormal spermatogenesis, asthenozoospermia, seminiferous tubule degeneration, abnormal seminiferous tubule morphology, female infertility, abnormal mating receptivity, reduced male mating frequency, oligozoospermia, male infertility, impaired fertilization, teratozoospermia, detached sperm flagellum, ovarian follicular cyst, pup cannibalization, abnormal mating receptivity, increased aggression towards females, reduced male mating frequency, abnormal pup retrieval, decreased bone ossification, short ulna, decreased bone mineralization, abnormal immunoglobulin level, abnormal response/metabolism to endogenous compounds, abnormal class switch recombination, abnormal bone marrow cell number, abnormal B cell number, increased circulating estradiol level, decreased osteoblast cell number, increased compact bone area, abnormal maternal nurturing, abnormal endometrium morphology, abnormal innervation, abnormal mesonephros morphology, abnormal uterus morphology, small uterus, skeleton phenotype, decreased circulating insulin-like growth factor I level, decreased length of long bones, decreased uterus weight, increased body weight, short femur Allele Detail: Targeted

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Cite this (MGI Cat# 3606700, RRID:MGI:3606700)

Source Database: MGI, catalog # 3606700
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Capn7
Genomic Alteration: tm1Dgen
Availability: Availability unknown check source stock center
Reference:
Notes: decreased body weight, preweaning lethality, incomplete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 4946609, RRID:MGI:4946609)

Source Database: MGI, catalog # 4946609
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Ranbp1
Genomic Alteration: tm1Yyo
Availability: Availability unknown check source stock center
Reference: PMID:21310149
Notes: postnatal growth retardation, azoospermia, male infertility, decreased body weight, abnormal male germ cell apoptosis, abnormal spermatogenesis, reproductive system phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 5781642, RRID:MGI:5781642)

Source Database: MGI, catalog # 5781642
Genetic Background: B6JTyr;B6N-Ide/Wtsi
Affected Genes: Ide
Genomic Alteration: tm1a(EUCOMM)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: abnormal cranium morphology, decreased circulating cholesterol level, decreased body weight, decreased total body fat amount, decreased circulating aspartate transaminase level, decreased circulating alanine transaminase level, abnormal maxilla morphology, abnormal incisor morphology, increased heart weight, increased circulating amylase level, abnormal hair texture Allele Detail: Targeted

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Cite this (MGI Cat# 3652539, RRID:MGI:3652539)

Source Database: MGI, catalog # 3652539
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Serp1
Genomic Alteration: tm1Hori
Availability: Availability unknown check source stock center
Reference: PMID:16705175
Notes: decreased circulating insulin level, postnatal lethality, incomplete penetrance, premature death, small adrenal glands, decreased body weight, abnormal skeletal muscle morphology, small pituitary gland, small adenohypophysis, decreased circulating growth hormone level, small thyroid gland, decreased bone mass, impaired glucose tolerance Allele Detail: Targeted

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