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on page 1 showing 20 out of 2,061 results

Cite this (MGI Cat# 3772884, RRID:MGI:3772884)

Source Database: MGI, catalog # 3772884
Genetic Background: FVB/N-Tg(Prnp-TBP*)71-27Xjl
Affected Genes:
Genomic Alteration: Tg(Prnp-TBP*)71-27Xjl
Availability: Availability unknown check source stock center
Reference: PMID:17994014
Notes: limb grasping, Purkinje cell degeneration, poor grooming, premature death, sporadic seizures, axon degeneration, weight loss, abnormal neuron morphology, abnormal neurite morphology, impaired coordination, decreased body size, gliosis, tremors Allele Detail: Transgenic

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Cite this (MGI Cat# 2662383, RRID:MGI:2662383)

Source Database: MGI, catalog # 2662383
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Affected Genes: Sp3
Genomic Alteration: tm1Sus
Availability: Availability unknown check source stock center
Reference: PMID:17584888
Notes: abnormal erythroid progenitor cell morphology, decreased body size Allele Detail: Targeted

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Cite this (MGI Cat# 3811816, RRID:MGI:3811816)

Source Database: MGI, catalog # 3811816
Genetic Background: involves: 129P2/OlaHsd * FVB/N
Affected Genes: Myc
Genomic Alteration: tm1Atp
Availability: Availability unknown check source stock center
Reference: PMID:11742404
Notes: spleen hypoplasia, decreased white adipose tissue amount, decreased T cell proliferation, lymphoid hypoplasia, lymph node hypoplasia, decreased body size, small lymphoid organs, postnatal growth retardation, decreased fetal size, decreased bone marrow cell number, decreased fibroblast proliferation, short tail, decreased body weight Allele Detail: Targeted

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Cite this (MGI Cat# 4359909, RRID:MGI:4359909)

Source Database: MGI, catalog # 4359909
Genetic Background: involves: 129S4/SvJaeSor
Affected Genes: Ghr
Genomic Alteration: tm1.2Masp
Availability: Availability unknown check source stock center
Reference: PMID:19460757
Notes: postnatal growth retardation, decreased body size Allele Detail: Targeted

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Cite this (MGI Cat# 5806513, RRID:MGI:5806513)

Source Database: MGI, catalog # 5806513
Genetic Background: C57BL/6J-Kbtbd2
Affected Genes: Kbtbd2
Genomic Alteration: m1Btlr
Availability: Availability unknown check source stock center
Reference: PMID:27708159
Notes: increased circulating alanine transaminase level, homeostasis/metabolism phenotype, increased circulating aspartate transaminase level, increased circulating insulin level, increased fasted circulating glucose level, increased lean body mass, increased liver triglyceride level, increased liver weight, insulin resistance, male infertility, pale liver, postnatal growth retardation, abnormal white adipose tissue physiology, decreased adiponectin level, decreased body size, enlarged liver, decreased inguinal fat pad weight, decreased epididymal fat pad weight, decreased circulating leptin level, decreased body weight, female infertility, hepatic steatosis Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 5521558, RRID:MGI:5521558)

Source Database: MGI, catalog # 5521558
Genetic Background: C57BL/6-Gt(ROSA)26Sor
Affected Genes: Gt(ROSA)26Sor
Genomic Alteration: tm4(H1/tetO-RNAi:Ezh2)Arte
Availability: Availability unknown check source stock center
Reference: PMID:23712803
Notes: small lymph nodes, impaired mammary gland growth during pregnancy, decreased mammary gland epithelial cell proliferation, decreased body size, abnormal mammary gland development, prenatal lethality, complete penetrance, abnormal mammary gland duct morphology Allele Detail: Targeted

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Cite this (MGI Cat# 2176329, RRID:MGI:2176329)

Source Database: MGI, catalog # 2176329
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Affected Genes: Marcks
Genomic Alteration: tm1Pjb
Availability: Availability unknown check source stock center
Reference: PMID:7862670, PMID:9184108, PMID:8922669
Notes: abnormal corpus callosum morphology, open neural tube, abnormal suckling behavior, abnormal cortical marginal zone morphology, perinatal lethality, incomplete penetrance, abnormal anterior commissure morphology, abnormal retina morphology, decreased brain size, exencephaly, dilated brain ventricles, decreased body size, ectopic neuron, microcephaly, omphalocele, abnormal brain development, abnormal cerebral cortex morphology, abnormal cortical marginal zone morphology, abnormal brain commissure morphology, abnormal hippocampal commissure morphology, abnormal scalp morphology, acrania Allele Detail: Targeted

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Cite this (MGI Cat# 6110172, RRID:MGI:6110172)

Source Database: MGI, catalog # 6110172
Genetic Background: involves: C57BL/6
Affected Genes: Ttc25
Genomic Alteration: em#Omra
Availability: Availability unknown check source stock center
Reference: PMID:27486780
Notes: dextrocardia, heterotaxia, lung situs inversus, hydroencephaly, impaired mucociliary clearance, absent nodal flow, decreased body size, preweaning lethality, incomplete penetrance Allele Detail: Endonuclease-mediated

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Cite this (MGI Cat# 5635532, RRID:MGI:5635532)

Source Database: MGI, catalog # 5635532
Genetic Background: involves: FVB/N * SKH1
Affected Genes:
Genomic Alteration: Tg(KRT14-rtTA)F42Efu; Tg(tetO-GJB2*G45E,-EGFP)#Tww
Availability: Availability unknown check source stock center
Reference: PMID:22031297
Notes: orthokeratosis, wrinkled skin, thick epidermis, postnatal lethality, incomplete penetrance, sebaceous gland atrophy, increased hair follicle apoptosis, hyperkeratosis, decreased body size, acanthosis, abnormal skin morphology, abnormal keratinocyte physiology, abnormal keratinocyte morphology, abnormal hair follicle morphology, abnormal epidermis stratum corneum morphology, abnormal epidermal layer morphology, scaly skin, abnormal dermal layer morphology, reddish skin Allele Detail: Transgenic

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Cite this (MGI Cat# 5770003, RRID:MGI:5770003)

Source Database: MGI, catalog # 5770003
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6N
Affected Genes: E2f1, Klhl40
Genomic Alteration: tm1.1Itl; tm1Njd
Availability: Availability unknown check source stock center
Reference: PMID:25940086
Notes: mortality/aging, decreased body size Allele Detail: Targeted

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Cite this (MGI Cat# 6157359, RRID:MGI:6157359)

Source Database: MGI, catalog # 6157359
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Eprs, Rps6kb1
Genomic Alteration: tm2.1Xen; tm1Nte
Availability: Availability unknown check source stock center
Reference: PMID:28178239
Notes: decreased epididymal fat pad weight, decreased body size, decreased inguinal fat pad weight, decreased interscapular fat pad weight, decreased mesenteric fat pad weight, decreased retroperitoneal fat pad weight Allele Detail: Targeted

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Cite this (MGI Cat# 3623123, RRID:MGI:3623123)

Source Database: MGI, catalog # 3623123
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Drd2
Genomic Alteration: tm1Schm
Availability: Availability unknown check source stock center
Reference: PMID:10391470
Notes: decreased body size, abnormal dopamine level, abnormal locomotor behavior, bradykinesia, decreased body weight, hunched posture, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 2656246, RRID:MGI:2656246)

Source Database: MGI, catalog # 2656246
Genetic Background: involves: 129S4/SvJae
Affected Genes: Sema3a
Genomic Alteration: tm1Mcf
Availability: Availability unknown check source stock center
Reference: PMID:8849723, PMID:18032673
Notes: heart right ventricle hypertrophy, premature death, abnormal cerebral cortex pyramidal cell morphology, weakness, abnormal sternum morphology, decreased survivor rate, thin cerebral cortex, decreased body size, dilated heart right ventricle, postnatal lethality, incomplete penetrance, dilated heart right atrium, split xiphoid process, abnormal cerebral cortex morphology, abnormal rib morphology, cervical vertebral fusion, respiratory system phenotype, decreased food intake, asymmetric sternocostal joints, rib fusion, abnormal posture, lethality at weaning, incomplete penetrance, abnormal sensory neuron innervation pattern, prenatal lethality, incomplete penetrance, abnormal neuron differentiation, decreased brain size Allele Detail: Targeted

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Cite this (MGI Cat# 4456087, RRID:MGI:4456087)

Source Database: MGI, catalog # 4456087
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Sirt1
Genomic Alteration: tm1Mcby
Availability: Availability unknown check source stock center
Reference: PMID:28273169, PMID:17877786
Notes: abnormal palatal rugae morphology, male infertility, female infertility, ocular hypotelorism, perinatal lethality, abnormal salivary gland morphology, decreased body size, increased autoantibody level, lethargy, short snout, female infertility, abnormal lacrimal gland morphology, decreased body size, hyperpnea, abnormal eyelid morphology, decreased body weight, eyelids fail to open, male infertility Allele Detail: Targeted

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Cite this (MGI Cat# 2174766, RRID:MGI:2174766)

Source Database: MGI, catalog # 2174766
Genetic Background: involves: 129/Sv * C57BL/6J * SJL
Affected Genes: Terc
Genomic Alteration: tm1Rdp
Availability: Availability unknown check source stock center
Reference: PMID:17360455, PMID:12505991, PMID:15084742, PMID:10064584, PMID:15731767, PMID:10654945, PMID:9335332, PMID:11809709
Notes: reduced female fertility, decreased fetal size, prenatal lethality, incomplete penetrance, abnormal telomere length, open neural tube, infertility, prenatal lethality, incomplete penetrance, decreased litter size, abnormal meiosis, hypoactivity, increased cardiomyocyte apoptosis, abnormal telomere length, abnormal developmental patterning, increased embryonic tissue cell apoptosis, increased left ventricle diastolic pressure, abnormal cardiovascular system physiology, abnormal fetal cardiomyocyte proliferation, abnormal myocardial fiber morphology, abnormal telomere length, abnormal cardiac muscle relaxation, weight loss, decreased left ventricle developed pressure, cardiac hypertrophy, congestive heart failure, premature death, abnormal cardiac muscle contractility, heart left ventricle hypertrophy, dilated cardiomyopathy, decreased myocardial fiber number, decreased heart left ventricle weight, decreased heart weight, abnormal telomere length, decreased incidence of tumors by chemical induction, homeostasis/metabolism phenotype, abnormal spleen B cell follicle morphology, abnormal telomere length, decreased spleen germinal center number, decreased T cell proliferation, increased B cell apoptosis, decreased B cell proliferation, abnormal angiogenesis, decreased incidence of induced tumors, abnormal telomere length, decreased body size, decreased body weight, abnormal male germ cell apoptosis, kyphosis, testicular atrophy, increased apoptosis, abnormal telomere length, abnormal male germ cell apoptosis, abnormal oocyte morphology, abnormal spermatocyte morphology, premature aging, abnormal male meiosis, abnormal female meiosis, abnormal chromosome morphology, abnormal intestine morphology, abnormal telomere length, alopecia Allele Detail: Targeted

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Cite this (MGI Cat# 2180387, RRID:MGI:2180387)

Source Database: MGI, catalog # 2180387
Genetic Background: involves: C57BLKS
Affected Genes: Itpr1
Genomic Alteration: opt
Availability: Availability unknown check source stock center
Reference: PMID:9302515, PMID:8530061, PMID:8987786
Notes: decreased body size, impaired coordination, impaired balance, abnormal locomotor behavior, lethality at weaning, complete penetrance, decreased body size, abnormal locomotor behavior, seizures, lethality at weaning, complete penetrance, opisthotonus, impaired righting response, lethality at weaning, complete penetrance, decreased body size, seizures, nervous system phenotype, abnormal cell physiology, weakness, seizures, nervous system phenotype, abnormal locomotor coordination Allele Detail: Spontaneous

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Cite this (MGI Cat# 5052337, RRID:MGI:5052337)

Source Database: MGI, catalog # 5052337
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J
Affected Genes: Arl13b, Pax3
Genomic Alteration: tm1(cre)Joe; hnn; tm1Tc
Availability: Availability unknown check source stock center
Reference: PMID:21539826
Notes: decreased body size, postnatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, respiratory distress Allele Detail: Chemically induced (ENU), Targeted

  • From Current Category

Cite this (MGI Cat# 5432002, RRID:MGI:5432002)

Source Database: MGI, catalog # 5432002
Genetic Background: involves: 129S4/SvJae * CD-1
Affected Genes: Vhl
Genomic Alteration: Tg(Sp7-tTA,tetO-EGFP/cre)1Amc; tm1Jae
Availability: Availability unknown check source stock center
Reference: PMID:22464323
Notes: increased osteoblast cell number, increased hematopoietic stem cell number, abnormal angiogenesis, increased trabecular bone mass, increased erythroid progenitor cell number, increased erythrocyte cell number, increased circulating erythropoietin level, increased bone trabecula number, extramedullary hematopoiesis, increased trabecular bone volume, polycythemia, increased hematocrit, enlarged spleen, decreased lymphocyte cell number, decreased bone marrow cell number, decreased body size, abnormal foot pad morphology, abnormal blood cell morphology/development Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 2677318, RRID:MGI:2677318)

Source Database: MGI, catalog # 2677318
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Recql4
Genomic Alteration: tm1Abe
Availability: Availability unknown check source stock center
Reference: PMID:12915449
Notes: growth retardation of incisors, abnormal small intestine morphology, postnatal lethality, incomplete penetrance, neonatal lethality, incomplete penetrance, decreased body weight, vision/eye phenotype, small thymus, abnormal long bone metaphysis morphology, skin lesions, postnatal growth retardation, alopecia, abnormal thymus corticomedullary boundary morphology, absent coat pigmentation, growth retardation of molars, decreased body size, decreased spleen white pulp amount Allele Detail: Targeted

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Cite this (MGI Cat# 5771805, RRID:MGI:5771805)

Source Database: MGI, catalog # 5771805
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * C57BL/6 * CBA
Affected Genes: Smarcb1, Trp53
Genomic Alteration: tm1Brn; tm2Sho; Tg(GFAP-cre)#Gtm
Availability: Availability unknown check source stock center
Reference: PMID:26363008
Notes: decreased survivor rate, decreased oligodendrocyte number, gliosis, abnormal limb posture, abnormal hippocampus morphology, abnormal brain white matter morphology, abnormal gait, increased brain tumor incidence, lethargy, seizures, tremors, circling, ataxia, decreased body weight, abnormal cerebellar granule cell migration, abnormal cerebral cortex morphology, abnormal cerebellum morphology, decreased body size, abnormal cerebellum external granule cell layer morphology, abnormal cerebellar layer morphology, impaired coordination, hindlimb paralysis, abnormal stride length, abnormal locomotor behavior, excessive scratching, abnormal corpus callosum morphology, dystonia Allele Detail: Targeted, Transgenic

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