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on page 1 showing 20 out of 3,868 results

Cite this (MGI Cat# 3770662, RRID:MGI:3770662)

Source Database: MGI, catalog # 3770662
Genetic Background: NOD.Cg-Prkdc Il2rg/Sz
Affected Genes: Prkdc, Il2rg
Genomic Alteration: tm1Wjl; scid
Availability: Availability unknown check source stock center
Reference: PMID:15879151, PMID:18785974
Notes: abnormal spleen B cell follicle morphology, lymph node hypoplasia, decreased mean corpuscular volume, abnormal response to transplant, decreased immature B cell number, increased cellular sensitivity to X-ray irradiation, premature death, decreased NK cell number, abnormal splenic cell ratio, decreased leukocyte cell number, abnormal response to transplant, decreased CD4-positive, alpha beta T cell number, decreased CD8-positive, alpha-beta T cell number, decreased immunoglobulin level, abnormal immune system organ morphology, abnormal thymus morphology, decreased mature B cell number, small lymph nodes Allele Detail: Spontaneous, Targeted

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Cite this (MGI Cat# 3761491, RRID:MGI:3761491)

Source Database: MGI, catalog # 3761491
Genetic Background: involves: C57BL/10 * CBA * FVB/N
Affected Genes: Lrfn2
Genomic Alteration: Tg(H2-K-Myc)1Brn; Tg(CD2-Myb/en)5Kmw
Availability: Availability unknown check source stock center
Reference: PMID:17577922
Notes: hemorrhage, abnormal erythropoiesis, abnormal lymph node morphology, enlarged lymph nodes, enlarged spleen, extramedullary hematopoiesis, abnormal common myeloid progenitor cell morphology, abnormal bone marrow cell morphology/development, premature death, spleen hyperplasia Allele Detail: Transgenic

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Cite this (MGI Cat# 5789376, RRID:MGI:5789376)

Source Database: MGI, catalog # 5789376
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * BALB/c * C57BL/6 * C57BL/6J
Affected Genes: Alk
Genomic Alteration: Tg(Th-MYCN)41Waw; tm2.1Ics
Availability: Availability unknown check source stock center
Reference: PMID:29321660, PMID:24811913
Notes: increased neuroblastoma incidence, premature death, increased neuroblastoma incidence Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 3770689, RRID:MGI:3770689)

Source Database: MGI, catalog # 3770689
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6
Affected Genes: Ngfr, Plg
Genomic Alteration: tm1Jld; tm1Jae
Availability: Availability unknown check source stock center
Reference: PMID:17395831
Notes: decreased body size, increased hepatocyte apoptosis, hepatic necrosis, premature death, increased hepatocyte proliferation Allele Detail: Targeted

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Cite this (MGI Cat# 4415196, RRID:MGI:4415196)

Source Database: MGI, catalog # 4415196
Genetic Background: B6.129-Idua
Affected Genes: Idua
Genomic Alteration: tm1.1Kmke
Availability: Availability unknown check source stock center
Reference: PMID:19751987
Notes: broad snout, short femur, decreased percent body fat/body weight, premature death, increased diameter of femur, increased bone mineral density, increased urine glycosaminoglycan level, abnormal zygomatic bone morphology, abnormal lysosome morphology, abnormal foam cell morphology Allele Detail: Targeted

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Cite this (MGI Cat# 3695429, RRID:MGI:3695429)

Source Database: MGI, catalog # 3695429
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6 * CBA * FVB/N
Affected Genes: Smad4, Kras, Cdkn2a
Genomic Alteration: Tg(Pdx1-cre)89.1Dam; tm4Rdp; tm1Rdp; tm4Tyj
Availability: Availability unknown check source stock center
Reference: PMID:17114584
Notes: increased pancreatic ductal adenocarcinoma incidence, premature death, increased tumor incidence, increased stomach tumor incidence Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 5790358, RRID:MGI:5790358)

Source Database: MGI, catalog # 5790358
Genetic Background: involves: 129S2/SvPas * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Affected Genes: Trp53
Genomic Alteration: tm2.1Umol; tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:23538418
Notes: increased reproductive system tumor incidence, decreased cellular sensitivity to gamma-irradiation, increased carcinoma incidence, increased lymphoma incidence, increased B cell derived lymphoma incidence, premature death, increased T cell derived lymphoma incidence, increased hematopoietic stem cell number, increased sarcoma incidence Allele Detail: Targeted

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Cite this (MGI Cat# 4441488, RRID:MGI:4441488)

Source Database: MGI, catalog # 4441488
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * BALB/cJ * C57BL/6 * FVB/N
Affected Genes: Pggt1b, Fntb, Kras, Lyz2
Genomic Alteration: tm1(cre)Ifo; tm1Mbrg; tm4Tyj; tm1.2Mbrg; tm1.1Mbrg
Availability: Availability unknown check source stock center
Reference: PMID:20308544
Notes: increased lung tumor incidence, decreased tumor growth/size, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 3652539, RRID:MGI:3652539)

Source Database: MGI, catalog # 3652539
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Serp1
Genomic Alteration: tm1Hori
Availability: Availability unknown check source stock center
Reference: PMID:16705175
Notes: small adenohypophysis, small thyroid gland, small pituitary gland, small adrenal glands, premature death, postnatal lethality, incomplete penetrance, impaired glucose tolerance, decreased circulating growth hormone level, decreased bone mass, decreased body weight, abnormal skeletal muscle morphology, decreased circulating insulin level Allele Detail: Targeted

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Cite this (MGI Cat# 3717420, RRID:MGI:3717420)

Source Database: MGI, catalog # 3717420
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
Affected Genes: Pthlh
Genomic Alteration: tm1Hmk; Tg(Col2a1-PTHLH)2Ecw; Tg(PTHLH)7Wmp
Availability: Availability unknown check source stock center
Reference: PMID:9751753
Notes: long lower incisors, premature death, malocclusion, short maxilla, decreased body weight, decreased body size, chondrodystrophy Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3045949, RRID:MGI:3045949)

Source Database: MGI, catalog # 3045949
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Kit
Genomic Alteration: tm3Ber
Availability: Availability unknown check source stock center
Reference: PMID:15067126
Notes: white spotting, absent coat pigmentation, abnormal coat/hair pigmentation, lethality at weaning, incomplete penetrance, variable depigmentation, increased megakaryocyte cell number, increased B cell number, premature death, reproductive system phenotype, decreased mast cell number, arrested B cell differentiation, spleen hyperplasia, enlarged spleen, meteorism, digestive/alimentary phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 6279211, RRID:MGI:6279211)

Source Database: MGI, catalog # 6279211
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Affected Genes: Krit1
Genomic Alteration: tm1Kwhi; Tg(Cdh5-cre/ERT2)1Rha
Availability: Availability unknown check source stock center
Reference: PMID:27027284, PMID:27513872
Notes: abnormal venule morphology, abnormal brain vasculature morphology, premature death, abnormal brain vasculature morphology Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2176491, RRID:MGI:2176491)

Source Database: MGI, catalog # 2176491
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Affected Genes: Ggt1
Genomic Alteration: tm1Zuk
Availability: Availability unknown check source stock center
Reference: PMID:8755578, PMID:11095909, PMID:12810527, PMID:11463821, PMID:11089562
Notes: cataract, abnormal postnatal growth/weight/body size, abnormal lens morphology, abnormal reproductive system development, cataract, male infertility, small testis, abnormal ovarian folliculogenesis, skeleton phenotype, abnormal long bone epiphyseal plate proliferative zone, decreased bone mass, disproportionate dwarf, absent corpus luteum, oligozoospermia, decreased circulating cysteine level, abnormal glucose homeostasis, abnormal body weight, premature death, premature death, female infertility, abnormal coat/hair pigmentation, nuclear cataracts, diluted coat color Allele Detail: Targeted

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Cite this (MGI Cat# 3776781, RRID:MGI:3776781)

Source Database: MGI, catalog # 3776781
Genetic Background: involves: C57BL/6J * CBA
Affected Genes: Del(MTmt-Tk-mt-Nd5)1Jiha
Genomic Alteration: Del(MTmt-Tk-mt-Nd5)1Jiha
Availability: Availability unknown check source stock center
Reference: PMID:15953585, PMID:16275929, PMID:15382041, PMID:17005726, PMID:11688994
Notes: increased pancreatic alpha cell number, glomerulosclerosis, pale kidney, enlarged kidney, abnormal mitochondrial ATP synthesis coupled electron transport, dilated renal tubules, dilated distal convoluted tubules, premature death, increased circulating lactate level, increased blood urea nitrogen level, enlarged kidney, decreased body weight, dilated proximal convoluted tubules, abnormal mitochondrial ATP synthesis coupled electron transport, abnormal postnatal growth, decreased circulating glucose level, increased circulating insulin level, impaired hearing, abnormal mitochondrial ATP synthesis coupled electron transport, increased insulin secretion, increased pancreatic beta cell number, pancreatic islet hyperplasia, decreased germ cell number, abnormal mitochondrial ATP synthesis coupled electron transport, decreased litter size, decreased body weight, deafness, asthenozoospermia, arrest of male meiosis, teratozoospermia, heart block, oligozoospermia, myopathy, male infertility, kidney failure, lactic acidosis, abnormal sperm nucleus morphology, abnormal sperm midpiece morphology, absent sperm head, reduced male mating frequency, abnormal mitochondrial crista morphology, abnormal mitochondrial ATP synthesis coupled electron transport, dilated mitochondria Allele Detail: Spontaneous

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Cite this (MGI Cat# 3624683, RRID:MGI:3624683)

Source Database: MGI, catalog # 3624683
Genetic Background: involves: 129S4/SvJaeSor
Affected Genes: Cdkn1b
Genomic Alteration: tm3Mlf; Tg(Pomc1-cre)1Mlf
Availability: Availability unknown check source stock center
Reference: PMID:16537495
Notes: premature death, decreased tumor incidence Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2668525, RRID:MGI:2668525)

Source Database: MGI, catalog # 2668525
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Affected Genes: Hprt
Genomic Alteration: tm4Detl
Availability: Availability unknown check source stock center
Reference: PMID:12812988
Notes: seizures, abnormal motor capabilities/coordination/movement, hypoactivity, abnormal reflex, neuronal intranuclear inclusions, premature death Allele Detail: Targeted

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Cite this (MGI Cat# 5429551, RRID:MGI:5429551)

Source Database: MGI, catalog # 5429551
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
Affected Genes: Stk36
Genomic Alteration: tm1Lex
Availability: Availability unknown check source stock center
Reference: PMID:21746835
Notes: abnormal craniofacial morphology, female infertility, growth/size/body region phenotype, hydrocephaly, decreased body length, decreased body weight, premature death, postnatal growth retardation, increased susceptibility to otitis media Allele Detail: Targeted

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Cite this (MGI Cat# 3057104, RRID:MGI:3057104)

Source Database: MGI, catalog # 3057104
Genetic Background: involves: BALB/cOlaHsd * C3H/HeH
Affected Genes: Rps7
Genomic Alteration: Mtu
Availability: Availability unknown check source stock center
Reference: PMID:15384171, PMID:23382688
Notes: belly spot, abnormal vertebral arch morphology, abnormal spatial working memory, thin cerebral cortex, premature death, belly spot, kinked tail, increased mean corpuscular volume, enlarged brain ventricles, curly tail, decreased body size, decreased vertebrae number Allele Detail: Chemically induced (ENU)

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Cite this (MGI Cat# 3706857, RRID:MGI:3706857)

Source Database: MGI, catalog # 3706857
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * C57BL/6 * CBA * FVB/N
Affected Genes: Foxo3, Foxo1, Tg(Mx1-cre)1Cgn
Genomic Alteration: Tg(Mx1-cre)1Cgn; tm1Rdp
Availability: Availability unknown check source stock center
Reference: PMID:17254969
Notes: increased hemangiosarcoma incidence, premature death, increased hepatic hemangioma incidence, increased tumor incidence, abnormal blood vessel morphology, increased hemangioma incidence Allele Detail: Transgenic, Targeted

  • From Current Category

Cite this (MGI Cat# 3844300, RRID:MGI:3844300)

Source Database: MGI, catalog # 3844300
Genetic Background: involves: 129S1/Sv * BALB/c
Affected Genes: Ank1
Genomic Alteration: RBC2
Availability: Availability unknown check source stock center
Reference: PMID:19179303
Notes: reticulocytosis, abnormal erythrocyte osmotic lysis, abnormal erythrocyte morphology, abnormal erythrocyte physiology, increased nucleated erythrocyte cell number, anemia, anisocytosis, decreased erythrocyte cell number, decreased hematocrit, decreased hemoglobin content, decreased mean corpuscular hemoglobin concentration, enlarged spleen, extramedullary hematopoiesis, increased circulating bilirubin level, increased hemoglobin concentration distribution width, increased liver iron level, jaundice, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, premature death, spherocytosis, poikilocytosis Allele Detail: Chemically induced (ENU)

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