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on page 1 showing 20 out of 1,337 results

Cite this (MGI Cat# 4946609, RRID:MGI:4946609)

Source Database: MGI, catalog # 4946609
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Ranbp1
Genomic Alteration: tm1Yyo
Availability: Availability unknown check source stock center
Reference: PMID:21310149
Notes: abnormal male germ cell apoptosis, decreased body weight, abnormal spermatogenesis, postnatal growth retardation, azoospermia, reproductive system phenotype, male infertility Allele Detail: Targeted

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Cite this (MGI Cat# 6120521, RRID:MGI:6120521)

Source Database: MGI, catalog # 6120521
Genetic Background: involves: C57BL/6 * SJL
Affected Genes: Myo9a
Genomic Alteration: tm1.2Bah
Availability: Availability unknown check source stock center
Reference: PMID:19828736
Notes: dilated lateral ventricles, abnormal gait, postnatal growth retardation, obstructive hydrocephaly, nervous system phenotype, enlarged third ventricle, brain ventricle stenosis, abnormal third ventricle morphology, abnormal neural tube ventricular layer morphology, abnormal cerebral aqueduct morphology Allele Detail: Targeted

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Cite this (MGI Cat# 2677718, RRID:MGI:2677718)

Source Database: MGI, catalog # 2677718
Genetic Background: C57BL/6J-Ghrhr
Affected Genes: Ghrhr
Genomic Alteration: lit
Availability: Availability unknown check source stock center
Reference: PMID:978118, PMID:7679139, PMID:12960295, PMID:12388430, PMID:12537301, PMID:1270792, PMID:6194978
Notes: decreased prolactin level, decreased somatotroph secretory granule number, abnormal metabolism, obese, decreased bone mass, abnormal postnatal growth, decreased somatotroph cell size, increased total body fat amount, decreased circulating growth hormone level, decreased somatotroph cell number, abnormal somatotroph morphology, absent somatotroph secretory granules, behavior/neurological phenotype, postnatal growth retardation, abnormal lactation, reduced male fertility, small pituitary gland, increased susceptibility to age related obesity, decreased growth hormone level, decreased susceptibility to experimental autoimmune encephalomyelitis, abnormal frequency of paradoxical sleep, abnormal sleep pattern, abnormal postnatal growth, abnormal skeleton development, proportional dwarf Allele Detail: Spontaneous

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Cite this (MGI Cat# 3033496, RRID:MGI:3033496)

Source Database: MGI, catalog # 3033496
Genetic Background: involves: 129 * C57BL/6J
Affected Genes: Suv39h1, Suv39h2
Genomic Alteration: tm1Jnw
Availability: Availability unknown check source stock center
Reference: PMID:11701123
Notes: arrest of male meiosis, small gonad, prenatal lethality, incomplete penetrance, postnatal growth retardation, infertility, decreased embryo size Allele Detail: Targeted

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Cite this (MGI Cat# 5429551, RRID:MGI:5429551)

Source Database: MGI, catalog # 5429551
Genetic Background: involves: 129S5/SvEvBrd * C57BL/6J
Affected Genes: Stk36
Genomic Alteration: tm1Lex
Availability: Availability unknown check source stock center
Reference: PMID:21746835
Notes: abnormal craniofacial morphology, female infertility, growth/size/body region phenotype, hydrocephaly, decreased body length, decreased body weight, premature death, postnatal growth retardation, increased susceptibility to otitis media Allele Detail: Targeted

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Cite this (MGI Cat# 5308984, RRID:MGI:5308984)

Source Database: MGI, catalog # 5308984
Genetic Background: involves: 129S7/SvEvBrd
Affected Genes: Asl
Genomic Alteration: tm1Brle
Availability: Availability unknown check source stock center
Reference: PMID:22081021
Notes: postnatal growth retardation, increased circulating citrulline level, increased macrophage cell number, increased circulating ammonia level, small hair follicles, decreased body weight, epidermal atrophy, decreased lymphocyte cell number, increased systemic arterial systolic blood pressure, increased systemic arterial diastolic blood pressure, increased spleen red pulp amount, acanthocytosis, abnormal renal glomerulus morphology, abnormal nitric oxide homeostasis, abnormal myocardial fiber morphology, decreased spleen germinal center number, abnormal hair follicle morphology, abnormal erythrocyte morphology, abnormal dermal layer morphology, decreased circulating alanine transaminase level, premature death, decreased circulating arginine level, decreased creatinine clearance, abnormal coat/ hair morphology, decreased circulating aspartate transaminase level, decreased vasodilation, thymus cortex hypoplasia Allele Detail: Targeted

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Cite this (MGI Cat# 4438913, RRID:MGI:4438913)

Source Database: MGI, catalog # 4438913
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Creb3l1
Genomic Alteration: tm1Kaim
Availability: Availability unknown check source stock center
Reference: PMID:19767743
Notes: fragile skeleton, postnatal growth retardation, decreased bone mineral density, decreased compact bone thickness, decreased bone ossification, abnormal osteoblast morphology, abnormal osteoblast differentiation, decreased bone mineralization, abnormal bone marrow cell morphology/development, decreased trabecular bone thickness Allele Detail: Targeted

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Cite this (MGI Cat# 5428212, RRID:MGI:5428212)

Source Database: MGI, catalog # 5428212
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Affected Genes: Apc2
Genomic Alteration: tm1Mno
Availability: Availability unknown check source stock center
Reference: PMID:22573669
Notes: impaired coordination, abnormal stratification in cerebral cortex, postnatal growth retardation, seizures, abnormal dentate gyrus morphology, abnormal fertility/fecundity, abnormal olfactory bulb mitral cell layer morphology, abnormal neuronal migration, abnormal hippocampus granule cell layer, abnormal hippocampus pyramidal cell layer, abnormal olfactory bulb layer morphology, long stride length, ectopic Purkinje cell, abnormal hippocampus layer morphology, ectopic cerebellar granule cells, increased neuron apoptosis, loss of cortex neurons, abnormal cerebellar layer morphology, abnormal cerebellar granule cell migration, ectopic hippocampus pyramidal cells Allele Detail: Targeted

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Cite this (MGI Cat# 3613012, RRID:MGI:3613012)

Source Database: MGI, catalog # 3613012
Genetic Background: involves: 129S6/SvEvTac
Affected Genes: Ncoa3
Genomic Alteration: tm1Jxu
Availability: Availability unknown check source stock center
Reference: PMID:10823921, PMID:14996752
Notes: disproportionate dwarf, abnormal branching of the mammary ductal tree, abnormal female reproductive system physiology, cachexia, decreased fibroblast cell migration, rough coat, preweaning lethality, incomplete penetrance, abnormal mammary gland development, delayed sexual maturation, decreased circulating insulin-like growth factor I level, prolonged estrous cycle, decreased litter size, decreased ovulation rate, decreased circulating estradiol level, abnormal vagina epithelium morphology, delayed vaginal opening, decreased body weight, postnatal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 3821760, RRID:MGI:3821760)

Source Database: MGI, catalog # 3821760
Genetic Background: involves: 129S/SvEv * C57BL/6J
Affected Genes: Igf1
Genomic Alteration: tm2Arge
Availability: Availability unknown check source stock center
Reference: PMID:19033454
Notes: decreased circulating insulin-like growth factor I level, postnatal growth retardation, abnormal long bone epiphyseal plate proliferative zone, decreased body weight, decreased long bone epiphyseal plate size, decreased survivor rate, infertility, neonatal lethality, incomplete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 4941332, RRID:MGI:4941332)

Source Database: MGI, catalog # 4941332
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Affected Genes: Lhx3
Genomic Alteration: tm1.1Sjr
Availability: Availability unknown check source stock center
Reference: PMID:21149718
Notes: reproductive system phenotype, abnormal thyroid follicle morphology, decreased activity of thyroid gland, abnormal fertility/fecundity, abnormal internal male genitalia morphology, abnormal sex gland secretion, reduced male fertility, endocrine/exocrine gland phenotype, premature death, postnatal growth retardation, abnormal craniofacial morphology, decreased lactotroph cell number, perinatal lethality, incomplete penetrance, decreased luteinizing hormone level, decreased prolactin level, abnormal pituitary gland morphology, abnormal pituitary hormone level, decreased survivor rate, decreased body size, cachexia, decreased adrenocorticotropin level, abnormal uterus morphology, small uterus, delayed sexual maturation, decreased uterus weight, azoospermia, abnormal uterus development, abnormal spermatogenesis, small testis, small seminal vesicle, small prostate gland, female infertility, decreased gonadotroph cell number, hearing/vestibular/ear phenotype, adenohypophysis hypoplasia, decreased circulating prolactin level, decreased circulating insulin-like growth factor I level, decreased circulating thyroxine level, decreased follicle stimulating hormone level Allele Detail: Targeted

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Cite this (MGI Cat# 3045844, RRID:MGI:3045844)

Source Database: MGI, catalog # 3045844
Genetic Background: involves: 129 * C57BL/6J
Affected Genes: Rfx3
Genomic Alteration: tm2.1Wrth
Availability: Availability unknown check source stock center
Reference: PMID:15121860
Notes: postnatal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 5571918, RRID:MGI:5571918)

Source Database: MGI, catalog # 5571918
Genetic Background: involves: C57BL/6 * C57BL/6JJcl
Affected Genes: Plg
Genomic Alteration: tm1.1Fjc
Availability: Availability unknown check source stock center
Reference: PMID:20653841
Notes: abnormal rectum morphology, postnatal growth retardation, enlarged lymph nodes, liver fibrosis, rectal prolapse, increased circulating fibrinogen level Allele Detail: Targeted

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Cite this (MGI Cat# 5691793, RRID:MGI:5691793)

Source Database: MGI, catalog # 5691793
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
Affected Genes: Lmna
Genomic Alteration: Gt(S7-1F1)Sor
Availability: Availability unknown check source stock center
Reference: PMID:21818413
Notes: prolonged RR interval, muscle weakness, prolonged P wave, decreased subcutaneous adipose tissue amount, decreased skeletal muscle fiber size, decreased skeletal muscle fiber diameter, increased circulating ketone body level, mortality/aging, hunched posture, poor grooming, decreased heart left ventricle weight, decreased body weight, abnormal suckling behavior, craniofacial phenotype, postnatal lethality, complete penetrance, decreased quadriceps weight, decreased heart rate, decreased grip strength, abnormal heart development, abnormal gait, abnormal fat cell differentiation, small myocardial fiber, skeleton phenotype, postnatal growth retardation, meteorism, increased circulating creatine kinase level, hypoglycemia, decreased liver glycogen level, decreased core body temperature, decreased circulating lactate level, decreased circulating carnitine level, abnormal mitochondrial ATP synthesis coupled electron transport Allele Detail: Gene trapped

  • From Current Category

Cite this (MGI Cat# 3803796, RRID:MGI:3803796)

Source Database: MGI, catalog # 3803796
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Tk2
Genomic Alteration: tm1Anka
Availability: Availability unknown check source stock center
Reference: PMID:18434326
Notes: postnatal growth retardation, decreased body temperature, abnormal myocardial fiber morphology, decreased mitochondrial DNA content, abnormal brown adipose tissue morphology, absent subcutaneous adipose tissue, abnormal hepatocyte morphology, abnormal adaptive thermogenesis, abnormal mitochondrial crista morphology, postnatal lethality, complete penetrance Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 4880746, RRID:MGI:4880746)

Source Database: MGI, catalog # 4880746
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
Affected Genes: Igf2
Genomic Alteration: tm1Snha
Availability: Availability unknown check source stock center
Reference: PMID:21148188
Notes: embryonic growth retardation, abnormal compact bone lamellar structure, decreased osteoblast cell number, abnormal tibia morphology, decreased bone mineral density, abnormal bone marrow cavity morphology, postnatal growth retardation, abnormal bone trabecula morphology, delayed bone ossification, abnormal cartilage development, abnormal skeleton morphology, abnormal osteoclast differentiation, abnormal osteoblast differentiation, abnormal skeleton development, increased compact bone thickness, fetal growth retardation, decreased birth weight, maternal imprinting Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 3582581, RRID:MGI:3582581)

Source Database: MGI, catalog # 3582581
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Rb1, Rbl1
Genomic Alteration: tm1Tyj
Availability: Availability unknown check source stock center
Reference: PMID:8682293
Notes: increased pituitary gland tumor incidence, abnormal retinal photoreceptor morphology, distended abdomen, abnormal perineum morphology, decreased body size, postnatal growth retardation, postnatal lethality, incomplete penetrance, abnormal retina morphology, vagina atresia, decreased body weight, premature death Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 3055152, RRID:MGI:3055152)

Source Database: MGI, catalog # 3055152
Genetic Background: involves: 129S2/SvPas * C57BL/6
Affected Genes: Pparg
Genomic Alteration: tm1Uls
Availability: Availability unknown check source stock center
Reference: PMID:15231871
Notes: postnatal growth retardation, decreased total body fat amount Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 5475097, RRID:MGI:5475097)

Source Database: MGI, catalog # 5475097
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Affected Genes: Ei24, Tg(Nes-cre)1Kln
Genomic Alteration: Tg(Nes-cre)1Kln; tm1Hzha
Availability: Availability unknown check source stock center
Reference: PMID:23074225, PMID:23479740
Notes: astrocytosis, abnormal cerebral cortex morphology, axonal dystrophy, abnormal brain white matter morphology, abnormal behavior, abnormal motor capabilities/coordination/movement, brain vacuoles, decreased Purkinje cell number, decreased myelin sheath thickness, decreased neuron number, neuronal cytoplasmic inclusions, reduced cerebellar foliation, thin cerebellar molecular layer, impaired autophagy, decreased cerebral cortex pyramidal cell number, premature death, postnatal growth retardation, limb grasping, increased neuron apoptosis, impaired coordination, enlarged lateral ventricles, decreased hippocampus pyramidal cell number, decreased body weight, axon degeneration, ataxia, nervous system phenotype, axonal spheroids, abnormal involuntary movement, abnormal hippocampus pyramidal cell layer, tremors, abnormal Purkinje cell morphology, abnormal axon morphology, abnormal cerebellum fissure morphology, abnormal nervous system morphology, thin cerebral cortex, abnormal oligodendrocyte morphology Allele Detail: Transgenic, Targeted

  • From Current Category

Cite this (MGI Cat# 5615442, RRID:MGI:5615442)

Source Database: MGI, catalog # 5615442
Genetic Background: CBA.Cg-Tshb
Affected Genes: Tshb
Genomic Alteration: tm1Hru
Availability: Availability unknown check source stock center
Reference: PMID:23758111
Notes: male infertility, female infertility, decreased body weight, postnatal growth retardation Allele Detail: Targeted

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