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on page 1 showing 19 out of 19 results

Cite this (MGI Cat# 3026782, RRID:MGI:3026782)

Source Database: MGI, catalog # 3026782
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Epha4
Genomic Alteration: tm1Byd
Availability: Availability unknown check source stock center
Reference: PMID:11182082, PMID:9789074, PMID:14699416, PMID:17035292
Notes: absent anterior commissure, abnormal corticospinal tract morphology, abnormal gait, abnormal innervation, abnormal spinal cord dorsal column morphology, impaired limb coordination, abnormal locomotor activation, abnormal innervation, abnormal barrel cortex morphology, abnormal gait, abnormal anterior commissure pars posterior morphology, abnormal anterior commissure morphology, abnormal corticospinal tract morphology, abnormal anterior commissure pars anterior morphology, abnormal primary somatosensory cortex morphology, abnormal placing response, nervous system phenotype, reduced long term potentiation Allele Detail: Targeted

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Cite this (MGI Cat# 3037821, RRID:MGI:3037821)

Source Database: MGI, catalog # 3037821
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Gnaq
Genomic Alteration: tm1Soff
Availability: Availability unknown check source stock center
Reference: PMID:9296496, PMID:12586747, PMID:11438569, PMID:9391157, PMID:11826096
Notes: neonatal lethality, incomplete penetrance, increased bleeding time, abnormal platelet physiology, impaired coordination, neonatal lethality, incomplete penetrance, nervous system phenotype, absent long term depression, abnormal nervous system electrophysiology, abnormal afterhyperpolarization, abnormal glutamate-mediated receptor currents, nervous system phenotype, ataxia, abnormal innervation, abnormal platelet physiology Allele Detail: Targeted

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Cite this (MGI Cat# 3606473, RRID:MGI:3606473)

Source Database: MGI, catalog # 3606473
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Tpp1
Genomic Alteration: tm1Dgen
Availability: Availability unknown check source stock center
Reference:
Notes: abnormal motor capabilities/coordination/movement, abnormal locomotor activation, ataxia, dehydration, hunched posture, tremors, respiratory distress, premature death, weakness, impaired coordination, increased thermal nociceptive threshold, seizures, tachypnea, abnormal gait Allele Detail: Targeted

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Cite this (MGI Cat# 2451132, RRID:MGI:2451132)

Source Database: MGI, catalog # 2451132
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Foxg1
Genomic Alteration: tm1(tTA)Lai; tm1M; Tg(tetO-Foxg1)1Lai
Availability: Availability unknown check source stock center
Reference: PMID:12151532
Notes: nervous system phenotype, abnormal telencephalon morphology, abnormal neuron differentiation, abnormal basal ganglion morphology, abnormal neural tube mantle layer morphology Allele Detail: Transgenic, Targeted

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Cite this (MGI Cat# 2176744, RRID:MGI:2176744)

Source Database: MGI, catalog # 2176744
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Bcl2l11
Genomic Alteration: tm1.1Ast
Availability: Availability unknown check source stock center
Reference: PMID:18275831, PMID:15210829, PMID:18032672, PMID:10576740
Notes: renal cast, increased CD8-positive, alpha-beta T cell number, increased IgG level, increased transitional stage B cell number, increased immature B cell number, increased IgM level, abnormal B cell proliferation, increased marginal zone B cell number, expanded mesangial matrix, increased follicular B cell number, increased IgA level, increased blood urea nitrogen level, decreased B cell apoptosis, increased anti-double stranded DNA antibody level, increased CD4-positive, alpha beta T cell number, abnormal lymphocyte physiology, premature death, glomerular crescent, abnormal renal glomerulus morphology, dilated renal tubules, vasculitis, abnormal spleen morphology, increased inflammatory response, enlarged spleen, increased granulocyte number, increased monocyte cell number, abnormal plasma cell morphology, decreased double-positive T cell number, nervous system phenotype, thrombocytopenia, embryonic lethality during organogenesis, incomplete penetrance, increased B cell number, increased T cell number, increased leukocyte cell number, increased double-negative T cell number, increased renal glomerulus apoptosis, abnormal kidney morphology, increased autoantibody level, abnormal renal glomerulus basement membrane morphology, increased anti-nuclear antigen antibody level, increased anti-single stranded DNA antibody level, increased anti-histone antibody level, increased splenocyte number, spleen hyperplasia, abnormal splenic cell ratio, increased susceptibility to autoimmune disorder, renal glomerular immunoglobulin deposits, glomerulonephritis Allele Detail: Targeted

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Cite this (MGI Cat# 4436909, RRID:MGI:4436909)

Source Database: MGI, catalog # 4436909
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Del(7Mrgpra1-Mrgprb4)1And
Genomic Alteration: Del(7Mrgpra1-Mrgprb4)1And
Availability: Availability unknown check source stock center
Reference: PMID:20004959
Notes: nervous system phenotype, decreased physiological sensitivity to xenobiotic, impaired behavioral response to xenobiotic, behavior/neurological phenotype, abnormal sensory neuron physiology, abnormal nociception after inflammation Allele Detail: Targeted

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Cite this (MGI Cat# 3029284, RRID:MGI:3029284)

Source Database: MGI, catalog # 3029284
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Sparcl1
Genomic Alteration: tm1Pmc
Availability: Availability unknown check source stock center
Reference: PMID:10611244
Notes: vision/eye phenotype, nervous system phenotype, reproductive system phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 2684625, RRID:MGI:2684625)

Source Database: MGI, catalog # 2684625
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Casp3
Genomic Alteration: tm1Flv
Availability: Availability unknown check source stock center
Reference: PMID:8934524, PMID:10578172, PMID:11150333, PMID:14985318, PMID:15599395
Notes: decreased body size, abnormal retina morphology, vision/eye phenotype, abnormal retinal pigment epithelium morphology, microphthalmia, abnormal eye development, abnormal blood vessel morphology, abnormal retinal inner nuclear layer morphology, nervous system phenotype, cellular phenotype, hydrocephaly, abnormal eye morphology, abnormal brain morphology, decreased thymocyte number, respiratory system phenotype, renal/urinary system phenotype, decreased apoptosis, abnormal optic stalk morphology, postnatal lethality, complete penetrance, abnormal brainstem morphology, immune system phenotype, prenatal lethality, incomplete penetrance, reproductive system phenotype, abnormal forebrain morphology, abnormal cerebellum development, abnormal cerebellar molecular layer, abnormal cerebellum external granule cell layer morphology, abnormal cerebellar granule layer morphology, abnormal diencephalon morphology, abnormal sagittal suture morphology, cranioschisis, abnormal osteoclast physiology, abnormal bone ossification, delayed bone ossification, decreased trabecular bone thickness, abnormal skeleton development, abnormal bone marrow development, cellular phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 3687871, RRID:MGI:3687871)

Source Database: MGI, catalog # 3687871
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Vax2
Genomic Alteration: tm1Grl
Availability: Availability unknown check source stock center
Reference: PMID:11830578
Notes: abnormal optic nerve innervation, microphthalmia, abnormal axon guidance, tremors, decreased body size Allele Detail: Targeted

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Cite this (MGI Cat# 3511176, RRID:MGI:3511176)

Source Database: MGI, catalog # 3511176
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Syngap1
Genomic Alteration: tm1.1Mabk
Availability: Availability unknown check source stock center
Reference: PMID:15470153, PMID:15733080
Notes: postnatal lethality, complete penetrance, abnormal motor capabilities/coordination/movement, tremors, weakness, abnormal hippocampus pyramidal cell morphology, increased neuron apoptosis, postnatal growth retardation, abnormal excitatory postsynaptic currents Allele Detail: Targeted

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Cite this (MGI Cat# 4834753, RRID:MGI:4834753)

Source Database: MGI, catalog # 4834753
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Lif
Genomic Alteration: tm1Stw
Availability: Availability unknown check source stock center
Reference: PMID:18521186, PMID:9651226, PMID:10712626, PMID:9740023
Notes: increased acute inflammation, increased vascular endothelial cell proliferation, abnormal retinal vasculature morphology, abnormal astrocyte morphology, abnormal induced retinal neovascularization, abnormal capillary morphology, abnormal brain vasculature morphology, abnormal blood vessel morphology, decreased susceptibility to injury, decreased susceptibility to injury, abnormal glial cell morphology, abnormal CNS glial cell morphology, nervous system phenotype, decreased body size, increased circulating interleukin-1 beta level Allele Detail: Targeted

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Cite this (MGI Cat# 3843809, RRID:MGI:3843809)

Source Database: MGI, catalog # 3843809
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Egr3, Ntf3
Genomic Alteration: tm1(cre)Mod; tm2Jae
Availability: Availability unknown check source stock center
Reference: PMID:19369542
Notes: nervous system phenotype, ataxia, abnormal posture, abnormal nervous system electrophysiology, abnormal gait Allele Detail: Targeted

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Cite this (MGI Cat# 2176762, RRID:MGI:2176762)

Source Database: MGI, catalog # 2176762
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Nf1
Genomic Alteration: tm1Cbr
Availability: Availability unknown check source stock center
Reference: PMID:11279521
Notes: abnormal discrimination learning, nervous system phenotype, impaired coordination, neoplasm, abnormal spatial learning Allele Detail: Targeted

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Cite this (MGI Cat# 5433181, RRID:MGI:5433181)

Source Database: MGI, catalog # 5433181
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Fezf2, Tbr1
Genomic Alteration: Tg(Emx1-cre)#Ito; tm1.1Nses; tm1Jlr; Tg(Mbp-MAPT/EGFP)#Eja
Availability: Availability unknown check source stock center
Reference: PMID:21285371
Notes: nervous system phenotype Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3522157, RRID:MGI:3522157)

Source Database: MGI, catalog # 3522157
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Tpp1
Genomic Alteration: tm1Plob
Availability: Availability unknown check source stock center
Reference: PMID:15483130
Notes: demyelination, tremors, decreased vertical activity, premature death, neurodegeneration, Purkinje cell degeneration, audiogenic seizures, abnormal lysosome physiology, abnormal gait, ataxia, impaired coordination Allele Detail: Targeted

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Cite this (MGI Cat# 3832407, RRID:MGI:3832407)

Source Database: MGI, catalog # 3832407
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Slc6a1
Genomic Alteration: tm1Mlit
Availability: Availability unknown check source stock center
Reference: PMID:16683252
Notes: decreased body weight, hyperactivity, increased startle reflex, tremors, abnormal bitter taste sensitivity, abnormal conditioned taste aversion behavior, abnormal behavioral response to xenobiotic, ataxia Allele Detail: Targeted

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Cite this (MGI Cat# 2175047, RRID:MGI:2175047)

Source Database: MGI, catalog # 2175047
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Grin1
Genomic Alteration: tm1Cur
Availability: Availability unknown check source stock center
Reference: PMID:8060614
Notes: absent gastric milk in neonates, atelectasis, nervous system phenotype, overexpanded pulmonary alveoli, perinatal lethality, complete penetrance, cardiovascular system phenotype, lung hemorrhage, cyanosis, abnormal glutamate-mediated receptor currents, absence of NMDA-mediated synaptic currents Allele Detail: Targeted

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Cite this (MGI Cat# 6121073, RRID:MGI:6121073)

Source Database: MGI, catalog # 6121073
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Dstyk
Genomic Alteration: tm1.2Zlh
Availability: Availability unknown check source stock center
Reference: PMID:25400726
Notes: impaired spatial learning, nervous system phenotype, behavior/neurological phenotype Allele Detail: Targeted

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Cite this (MGI Cat# 3528141, RRID:MGI:3528141)

Source Database: MGI, catalog # 3528141
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Cpe
Genomic Alteration: tm1Yplo
Availability: Availability unknown check source stock center
Reference: PMID:15358678
Notes: abnormal gait, abnormal motor capabilities/coordination/movement, obese, abnormal muscle physiology, increased total body fat amount, abnormal energy expenditure, abnormal hypothalamus secretion, insulin resistance, abnormal glucose homeostasis, increased circulating leptin level, hypoactivity, impaired glucose tolerance, increased circulating glucose level, lethargy, polyphagia, hyporesponsive to tactile stimuli, increased respiratory quotient, reduced fertility, increased circulating insulin level, decreased vertical activity, tremors, abnormal motor coordination/balance, abnormal physical strength, decreased grip strength, abnormal placing response, increased body length Allele Detail: Targeted

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