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on page 1 showing 20 out of 1,145 results

Cite this (MGI Cat# 3796157, RRID:MGI:3796157)

Source Database: MGI, catalog # 3796157
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N
Affected Genes: Mirc1
Genomic Alteration: tm1.3Tyj
Availability: Availability unknown check source stock center
Reference: PMID:18329372
Notes: pulmonary hypoplasia, decreased pre-B cell number, increased B cell apoptosis, neonatal lethality, complete penetrance, decreased embryo size, abnormal B cell differentiation, decreased embryo weight, abnormal interventricular septum morphology Allele Detail: Targeted

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Cite this (MGI Cat# 4397490, RRID:MGI:4397490)

Source Database: MGI, catalog # 4397490
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
Affected Genes: Ilk
Genomic Alteration: tm9.1Ref
Availability: Availability unknown check source stock center
Reference: PMID:19829382
Notes: decreased nephron number, abnormal mesonephros morphology, integument phenotype, single kidney, renal hypoplasia, decreased kidney collecting duct number, increased metanephric mesenchyme apoptosis, pallor, neonatal lethality, complete penetrance, impaired branching involved in ureteric bud morphogenesis, hunched posture, aphagia, decreased birth body size, cardiovascular system phenotype, anuria, absent ureter, absent kidney, abnormal ureteric bud invasion Allele Detail: Targeted

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Cite this (MGI Cat# 4442806, RRID:MGI:4442806)

Source Database: MGI, catalog # 4442806
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Affected Genes: Pggt1b
Genomic Alteration: Tg(KRT14-cre)1Amc; tm1Mbrg
Availability: Availability unknown check source stock center
Reference: PMID:20106865
Notes: neonatal lethality, complete penetrance, decreased keratinocyte proliferation, underdeveloped hair follicles Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3768261, RRID:MGI:3768261)

Source Database: MGI, catalog # 3768261
Genetic Background: Not Specified
Affected Genes: Chst11
Genomic Alteration: Gt(PT-1)1Wran
Availability: Availability unknown check source stock center
Reference: PMID:16079159
Notes: short limbs, abnormal vertebral column morphology, decreased length of long bones, domed cranium, short mandible, small scapula, disproportionate dwarf, increased diameter of long bones, neonatal lethality, complete penetrance, respiratory distress, short facial bone, abnormal vertebral arch morphology, abnormal phalanx morphology, short maxilla, abnormal cartilage morphology, abnormal epiphyseal plate morphology, abnormal long bone hypertrophic chondrocyte zone, short nasal bone, abnormal talus morphology, small thoracic cage, abnormal vertebrae morphology, wide ilium, short ilium Allele Detail: Gene trapped

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Cite this (MGI Cat# 3765972, RRID:MGI:3765972)

Source Database: MGI, catalog # 3765972
Genetic Background: involves: 129 * C57BL/6
Affected Genes: Ltbp1
Genomic Alteration: tm2Veto
Availability: Availability unknown check source stock center
Reference: PMID:17804598
Notes: abnormal vascular smooth muscle morphology, right aortic arch, lethality throughout fetal growth and development, incomplete penetrance, perimembraneous ventricular septal defect, cyanosis, common atrium, abnormal cardiac neural crest cell morphology, neonatal lethality, complete penetrance, abnormal truncus arteriosus septation, interrupted aortic arch, abnormal fourth pharyngeal arch artery morphology, abnormal ascending aorta and coronary artery attachment, persistent truncus arteriosis Allele Detail: Targeted

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Cite this (MGI Cat# 3033457, RRID:MGI:3033457)

Source Database: MGI, catalog # 3033457
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)
Affected Genes: Dph1
Genomic Alteration: tm2Bhr
Availability: Availability unknown check source stock center
Reference: PMID:14744934
Notes: hydrops fetalis, decreased fetal weight, primary atelectasis, thick lung-associated mesenchyme, abnormal hepatoblast morphology, respiratory failure, embryonic growth retardation, preaxial polydactyly, neonatal lethality, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, abnormal cell cycle, cleft palate, abnormal somite development, abnormal skeleton development, abnormal neural tube morphology, abnormal lung development, liver degeneration, abnormal eye pigmentation, abnormal eye morphology, increased nucleated erythrocyte cell number, abnormal embryo turning, abnormal craniofacial bone morphology, embryonic lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 2176961, RRID:MGI:2176961)

Source Database: MGI, catalog # 2176961
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA/2J) or (involves: 129S1/Sv * 129X1/SvJ * FVB/N)
Affected Genes: Gbx2
Genomic Alteration: tm1.1Mrt
Availability: Availability unknown check source stock center
Reference: PMID:9247335
Notes: abnormal midbrain-hindbrain boundary development, abnormal metencephalon morphology, absent supraoccipital bone, abnormal forebrain development, abnormal midbrain development, abnormal inferior colliculus morphology, abnormal membranous labyrinth morphology, abnormal cerebellum development, absent cerebellum, neonatal lethality, complete penetrance, abnormal pons morphology, abnormal motor neuron morphology, abnormal midbrain morphology, abnormal hindbrain morphology, abnormal choroid plexus morphology, small otic vesicle, abnormal locus ceruleus morphology, abnormal midbrain-hindbrain boundary morphology Allele Detail: Targeted

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Cite this (MGI Cat# 3692116, RRID:MGI:3692116)

Source Database: MGI, catalog # 3692116
Genetic Background: Not Specified
Affected Genes: Six2
Genomic Alteration: tm1Gco
Availability: Availability unknown check source stock center
Reference: PMID:17036046
Notes: impaired branching involved in ureteric bud morphogenesis, abnormal nephron morphology, abnormal kidney cortex morphology, abnormal kidney development, abnormal kidney morphology, small kidney, renal hypoplasia, neonatal lethality, complete penetrance, abnormal nephron number Allele Detail: Targeted

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Cite this (MGI Cat# 2175209, RRID:MGI:2175209)

Source Database: MGI, catalog # 2175209
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI
Affected Genes: Pax6
Genomic Alteration: tm1Pgr
Availability: Availability unknown check source stock center
Reference: PMID:9163426
Notes: neonatal lethality, complete penetrance, absent olfactory bulb, disorganized pancreatic islets, anophthalmia, absent pancreatic alpha cells Allele Detail: Targeted

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Cite this (MGI Cat# 3848502, RRID:MGI:3848502)

Source Database: MGI, catalog # 3848502
Genetic Background: involves: 129S4/SvJae * C57BL/6J
Affected Genes: Six2
Genomic Alteration: tm2(cre/ERT2)Amc
Availability: Availability unknown check source stock center
Reference: PMID:18682239
Notes: neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 3723223, RRID:MGI:3723223)

Source Database: MGI, catalog # 3723223
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Affected Genes: Pds5b
Genomic Alteration: tm1Jmi
Availability: Availability unknown check source stock center
Reference: PMID:17652350
Notes: short chin, microcephaly, abnormal sternum ossification, cyanosis, decreased birth body size, decreased rib number, abnormal palatal shelf fusion at midline, delayed bone ossification, abnormal enteric nervous system morphology, abnormal heart morphology, abnormal craniofacial bone morphology, short sternum, abnormal long bone morphology, short snout, abnormal axial skeleton morphology, thin upper lip, short scapula, short radius, palatal shelves fail to meet at midline, abnormal superior cervical ganglion morphology, short mandible, abnormal chin morphology, perimembraneous ventricular septal defect, lethality throughout fetal growth and development, incomplete penetrance, short limbs, short humerus, respiratory distress, abnormal palate bone morphology, abnormal vertebrae development, cleft secondary palate, short ulna, decreased germ cell number, ostium secundum atrial septal defect, abnormal facial morphology, decreased male germ cell number, neonatal lethality, complete penetrance, rib fusion, abnormal hyoid bone morphology, complete atrioventricular septal defect, pallor, ventricular septal defect, abnormal sympathetic postganglionic fiber morphology, fetal growth retardation Allele Detail: Targeted

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Cite this (MGI Cat# 2669271, RRID:MGI:2669271)

Source Database: MGI, catalog # 2669271
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss
Affected Genes: Proc
Genomic Alteration: tm1Fjc
Availability: Availability unknown check source stock center
Reference: PMID:9788960
Notes: intracranial hemorrhage, focal hepatic necrosis, liver fibrosis, abnormal blood coagulation, neonatal lethality, complete penetrance, abnormal thrombosis, liver inflammation, perinatal lethality, complete penetrance, abnormal innate immunity, abnormal suckling behavior, bruising, liver degeneration Allele Detail: Targeted

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Cite this (MGI Cat# 2680673, RRID:MGI:2680673)

Source Database: MGI, catalog # 2680673
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * ICR
Affected Genes: Dlg1
Genomic Alteration: Gt(gt1.8geo)1Ber
Availability: Availability unknown check source stock center
Reference: PMID:11238884, PMID:14645510, PMID:16105026
Notes: small metanephros, domed cranium, abnormal palatal shelf elevation, absent gastric milk in neonates, meteorism, curly tail, distended abdomen, fetal growth retardation, cleft secondary palate, cyanosis, neonatal lethality, complete penetrance, short snout, decreased body size, kinked tail, mandible hypoplasia, premaxilla hypoplasia, abnormal lens epithelium morphology, abnormal kidney development, decreased fetal size, decreased nephron number, decreased embryo weight, decreased renal glomerulus number Allele Detail: Gene trapped

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Cite this (MGI Cat# 3773540, RRID:MGI:3773540)

Source Database: MGI, catalog # 3773540
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Affected Genes: Hoxa2
Genomic Alteration: tm1.2Fmr
Availability: Availability unknown check source stock center
Reference: PMID:11857791
Notes: neonatal lethality, complete penetrance, abnormal craniofacial morphology, abnormal ear morphology, abnormal nervous system morphology, abnormal skeleton morphology, abnormal behavior Allele Detail: Targeted

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Cite this (MGI Cat# 4829788, RRID:MGI:4829788)

Source Database: MGI, catalog # 4829788
Genetic Background: involves: 129 * C57BL/6 * SJL
Affected Genes: Foxp1, Nkx2-5
Genomic Alteration: tm1(cre)Rjs; tm2.1Eem
Availability: Availability unknown check source stock center
Reference: PMID:20713518
Notes: thick interventricular septum, abnormal heart development, abnormal sarcomere morphology, ventricular septal defect, double outlet right ventricle, neonatal lethality, complete penetrance, thick ventricular wall, increased fetal cardiomyocyte proliferation Allele Detail: Targeted

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Cite this (MGI Cat# 4431248, RRID:MGI:4431248)

Source Database: MGI, catalog # 4431248
Genetic Background: involves: 101/H * C3H/HeH
Affected Genes: Del(7)Tyr
Genomic Alteration: c-3H
Availability: Availability unknown check source stock center
Reference: PMID:4296364
Notes: abnormal kidney morphology, hypoglycemia, small kidney, decreased circulating glucose level, abnormal thymus morphology, absent skin pigmentation, abnormal skin pigmentation, neonatal lethality, complete penetrance Allele Detail: Radiation induced

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Cite this (MGI Cat# 5305444, RRID:MGI:5305444)

Source Database: MGI, catalog # 5305444
Genetic Background: involves: 129S6/SvEvTac
Affected Genes: Olig2, Cdh2
Genomic Alteration: tm1(cre)Tmj; tm1Glr
Availability: Availability unknown check source stock center
Reference: PMID:22036570
Notes: lethality throughout fetal growth and development, incomplete penetrance, abnormal neuronal migration, neonatal lethality, complete penetrance, abnormal spinal cord morphology, abnormal spinal cord motor column morphology Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 3589666, RRID:MGI:3589666)

Source Database: MGI, catalog # 3589666
Genetic Background: involves: 129X1/SvJ * CD-1
Affected Genes: Gdf11
Genomic Alteration: tm1Clf
Availability: Availability unknown check source stock center
Reference: PMID:15976303, PMID:12546816
Notes: decreased retinal photoreceptor cell number, absent sacral vertebrae, delayed optic fissure closure, increased retinal ganglion cell number, absent tail, decreased caudal vertebrae number, abnormal optic nerve morphology, abnormal neuron differentiation, abnormal olfactory epithelium morphology, abnormal hindlimb morphology, abnormal kidney development, absent retinal inner plexiform layer, neonatal lethality, complete penetrance, increased neuronal precursor cell number, vertebral transformation, abnormal olfactory sensory neuron morphology, absent amacrine cells Allele Detail: Targeted

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Cite this (MGI Cat# 2655238, RRID:MGI:2655238)

Source Database: MGI, catalog # 2655238
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Affected Genes: Grin1
Genomic Alteration: tm2Slab; tm1.1Slab
Availability: Availability unknown check source stock center
Reference: PMID:12657691
Notes: cyanosis, abnormal trigeminal nerve morphology, abnormal nervous system electrophysiology, neonatal lethality, complete penetrance, abnormal brainstem morphology, respiratory distress Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 3702287, RRID:MGI:3702287)

Source Database: MGI, catalog # 3702287
Genetic Background: either: (involves: C57BL/6 * CBA) or (involves: C57BL/6 * CBA * ICR)
Affected Genes: Mesp2
Genomic Alteration: tm1Ysa
Availability: Availability unknown check source stock center
Reference: PMID:9242490
Notes: abnormal dermomyotome development, abnormal somite border morphology, abnormal rostral-caudal patterning of the somites, fusion of vertebral arches, abnormal sclerotome morphology, abnormal vertebral lamina morphology, vertebral fusion, cervical vertebral fusion, incomplete somite formation, integument phenotype, muscle phenotype, fused dorsal root ganglion, decreased body length, neonatal lethality, complete penetrance, vestigial tail, abnormal vertebrae morphology, abnormal axon extension, delayed somite formation, rib fusion, absent intervertebral disk, abnormal paraxial mesoderm morphology, spina bifida, lumbar vertebral fusion Allele Detail: Targeted

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