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on page 1 showing 20 out of 1,145 results

Cite this (MGI Cat# 5903213, RRID:MGI:5903213)

Source Database: MGI, catalog # 5903213
Genetic Background: involves: C57BL/6J
Affected Genes: Mymx
Genomic Alteration: em1Shcs
Availability: Availability unknown check source stock center
Reference: PMID:28569755
Notes: nuchal edema, abnormal myoblast fusion, abnormal muscle morphology, muscle weakness, abnormal hypaxial muscle morphology, primary atelectasis, neonatal lethality, complete penetrance, decreased fetal weight, abnormal intercostal muscle morphology, abnormal limb morphology, abnormal skeletal muscle morphology, abnormal spine curvature, cyanosis Allele Detail: Endonuclease-mediated

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Cite this (MGI Cat# 3849330, RRID:MGI:3849330)

Source Database: MGI, catalog # 3849330
Genetic Background: either: (involves: 129S1/Sv * 129X1/SvJ) or (involves: 129S6/SvEvTac * C57BL/6NCr)
Affected Genes: Celsr3
Genomic Alteration: tm1Mrc
Availability: Availability unknown check source stock center
Reference: PMID:19332558
Notes: abnormal neuronal migration, neonatal lethality, complete penetrance, nervous system phenotype, abnormal globus pallidus morphology, abnormal innervation, abnormal embryonic/fetal subventricular zone morphology Allele Detail: Targeted

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Cite this (MGI Cat# 6295938, RRID:MGI:6295938)

Source Database: MGI, catalog # 6295938
Genetic Background: involves: C57BL/6J * C57BL/6N
Affected Genes: Amotl1
Genomic Alteration: em1Rstot
Availability: Availability unknown check source stock center
Reference: PMID:30375152
Notes: neonatal lethality, complete penetrance, cardiovascular system phenotype, craniofacial phenotype, prenatal lethality, incomplete penetrance Allele Detail: Endonuclease-mediated

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Cite this (MGI Cat# 4421509, RRID:MGI:4421509)

Source Database: MGI, catalog # 4421509
Genetic Background: involves: C57BL/6 * CBA
Affected Genes: Bnc2
Genomic Alteration: Gt(pU21)18Imeg
Availability: Availability unknown check source stock center
Reference: PMID:19706529
Notes: palatal shelves fail to meet at midline, neonatal lethality, complete penetrance, abnormal palate development, abnormal pterygoid process morphology, cleft secondary palate, decreased birth body size, large posterior fontanelle, decreased tongue size, frontal bone hypoplasia, microcephaly, parietal bone hypoplasia, small alisphenoid bone, absent palatine bone, wide sagittal suture, meteorism, abnormal maxillary shelf morphology Allele Detail: Gene trapped

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Cite this (MGI Cat# 2663890, RRID:MGI:2663890)

Source Database: MGI, catalog # 2663890
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)
Affected Genes: Fah
Genomic Alteration: tm1Mgo
Availability: Availability unknown check source stock center
Reference: PMID:8253378
Notes: abnormal circulating aspartate transaminase level, hypoglycemia, increased circulating creatinine level, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 3723640, RRID:MGI:3723640)

Source Database: MGI, catalog # 3723640
Genetic Background: involves: 129S2/SvPas * BALB/c * C57BL/6 * SJL
Affected Genes: Tg(Pgk1-cre)1Lni, Pax9
Genomic Alteration: tm1.1Hpt; Tg(Pgk1-cre)1Lni
Availability: Availability unknown check source stock center
Reference: PMID:17610273
Notes: abnormal thymus lobule morphology, absent parathyroid glands, absent premaxilla, aphagia, cleft secondary palate, abnormal maxillary shelf morphology, neonatal lethality, complete penetrance, polydactyly, absent teeth, absent mandibular coronoid process, abnormal tympanic ring morphology, abnormal palatine bone horizontal plate morphology Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 2175079, RRID:MGI:2175079)

Source Database: MGI, catalog # 2175079
Genetic Background: involves: 129S/SvEv
Affected Genes: Igf1r
Genomic Alteration: tm1Arge
Availability: Availability unknown check source stock center
Reference: PMID:8402901
Notes: abnormal brainstem morphology, decreased birth weight, neonatal lethality, complete penetrance, respiratory failure, muscle hypoplasia, delayed bone ossification, abnormal spinal cord morphology, translucent skin, decreased hair follicle number, thin epidermis stratum spinosum, small hair follicles, decreased oligodendrocyte progenitor number, cyanosis, atelectasis, abnormal hair follicle morphology, thin epidermis Allele Detail: Targeted

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Cite this (MGI Cat# 6314225, RRID:MGI:6314225)

Source Database: MGI, catalog # 6314225
Genetic Background: involves: 129S1/Sv * C57BL/6J
Affected Genes: Atp1a2
Genomic Alteration: tm1.1Tmklh
Availability: Availability unknown check source stock center
Reference: PMID:26911348
Notes: abnormal hippocampus physiology, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 2175131, RRID:MGI:2175131)

Source Database: MGI, catalog # 2175131
Genetic Background: involves: 129S1/Sv * C57BL/6
Affected Genes: Myf6
Genomic Alteration: tm1Wb
Availability: Availability unknown check source stock center
Reference: PMID:7588068
Notes: rib bifurcation, abnormal cervical vertebrae morphology, respiratory distress, abnormal myotome morphology, abnormal intercostal muscle morphology, abnormal myotome development, abnormal sternum ossification, short ribs, neonatal lethality, complete penetrance, truncated ribs, abnormal sternocostal joint morphology, abnormal rib morphology, rib fusion Allele Detail: Targeted

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Cite this (MGI Cat# 3521928, RRID:MGI:3521928)

Source Database: MGI, catalog # 3521928
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * 129X1/SvJ
Affected Genes: Top2b, Foxg1
Genomic Alteration: tm2Jcw; tm2.1Jcw; tm1(cre)Skm
Availability: Availability unknown check source stock center
Reference: PMID:12773624
Notes: respiratory failure, abnormal motor capabilities/coordination/movement, abnormal hippocampus granule cell layer, abnormal hippocampus morphology, small olfactory bulb, atelectasis, abnormal hippocampus pyramidal cell layer, neonatal lethality, complete penetrance, abnormal cerebral cortex morphology Allele Detail: Targeted

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Cite this (MGI Cat# 6150914, RRID:MGI:6150914)

Source Database: MGI, catalog # 6150914
Genetic Background: involves: C57BL/6J * CD-1
Affected Genes: Rnf146
Genomic Alteration: tm1.1Rtpl; Tg(Sp7-tTA,tetO-EGFP/cre)1Amc
Availability: Availability unknown check source stock center
Reference: PMID:28581440
Notes: decreased compact bone thickness, decreased bone ossification, decreased circulating insulin level, decreased osteoblast cell number, decreased osteoblast proliferation, impaired glucose tolerance, increased total body fat amount, increased bone marrow adipose tissue amount, decreased pancreatic islet number, decreased insulin secretion, increased circulating glucose level, abnormal circulating osteocalcin level, increased circulating triglyceride level, clavicle hypoplasia, skeleton phenotype, respiratory distress, neonatal lethality, complete penetrance, large posterior fontanelle, large anterior fontanelle, increased bone trabecular spacing, impaired osteoblast differentiation, decreased trabecular bone volume, decreased compact bone volume, decreased bone trabecula number, decreased bone mineralization, decreased bone mineral density, small pancreatic islets, abnormal rib morphology, abnormal limb long bone morphology, abnormal intramembranous bone ossification, abnormal endochondral bone ossification, abnormal ameloblast differentiation, abnormal alveolar process morphology Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3687545, RRID:MGI:3687545)

Source Database: MGI, catalog # 3687545
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Affected Genes: Shh
Genomic Alteration: tm2Chg
Availability: Availability unknown check source stock center
Reference: PMID:16611729
Notes: neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 3722142, RRID:MGI:3722142)

Source Database: MGI, catalog # 3722142
Genetic Background: involves: 129/Sv * 129S2/SvPas
Affected Genes: Hoxa2, Hoxb2
Genomic Alteration: tm1Fmr; tm1Ipc
Availability: Availability unknown check source stock center
Reference: PMID:10230789
Notes: increased rhombomere 1 size, abnormal rhombomere morphology, neonatal lethality, complete penetrance Allele Detail: Targeted

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Cite this (MGI Cat# 3510314, RRID:MGI:3510314)

Source Database: MGI, catalog # 3510314
Genetic Background: either: 129/Sv or (involves: 129/Sv * C57BL/6)
Affected Genes: Tbx1
Genomic Alteration: tm1.1Dsr
Availability: Availability unknown check source stock center
Reference: PMID:15469978
Notes: anotia, right aortic arch, small cricoid cartilage, double outlet right ventricle, athymia, cleft secondary palate, palatal shelves fail to meet at midline, abnormal middle ear ossicle morphology, aberrant origin of the right subclavian artery, persistent truncus arteriosis, double aortic arch, fusion of basioccipital and basisphenoid bone, abnormal inner ear morphology, abnormal hyoid bone morphology, decreased tympanic ring size, neonatal lethality, complete penetrance, ventricular septal defect, abnormal stapes morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5301973, RRID:MGI:5301973)

Source Database: MGI, catalog # 5301973
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6
Affected Genes: Lmnb2, Lmnb1
Genomic Alteration: tm1Yxz
Availability: Availability unknown check source stock center
Reference: PMID:22116031
Notes: microcephaly, thin cerebral cortex, decreased embryo size, neonatal lethality, complete penetrance, abnormal pulmonary alveolus morphology, decreased fetal size, abnormal cell physiology, respiratory failure, thin diaphragm muscle, abnormal phrenic nerve innervation pattern to diaphragm, abnormal neuron differentiation, abnormal neuronal migration, abnormal neuronal precursor proliferation, abnormal stratification in cerebral cortex, increased neuronal precursor cell number Allele Detail: Targeted

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Cite this (MGI Cat# 3773315, RRID:MGI:3773315)

Source Database: MGI, catalog # 3773315
Genetic Background: involves: 129S4/SvJae * C57BL/6
Affected Genes: Pbx3
Genomic Alteration: tm1.1Og
Availability: Availability unknown check source stock center
Reference: PMID:18155191
Notes: neonatal lethality, complete penetrance, cyanosis Allele Detail: Targeted

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Cite this (MGI Cat# 2175049, RRID:MGI:2175049)

Source Database: MGI, catalog # 2175049
Genetic Background: either: (involves: 129S2/SvPas * 129/Sv) or (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL/6)
Affected Genes: Grin1
Genomic Alteration: tm1Stl
Availability: Availability unknown check source stock center
Reference: PMID:8313466
Notes: apnea, neonatal lethality, complete penetrance, cyanosis, absence of NMDA-mediated synaptic currents, abnormal brainstem morphology, ataxia, abnormal suckling behavior Allele Detail: Targeted

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Cite this (MGI Cat# 3701801, RRID:MGI:3701801)

Source Database: MGI, catalog # 3701801
Genetic Background: involves: 129X1/SvJ * C57BL/6
Affected Genes: Ptges3
Genomic Alteration: Gt(W069F07)Wrst
Availability: Availability unknown check source stock center
Reference: PMID:17000766
Notes: decreased type II pneumocyte number, abnormal breathing pattern, abnormal surfactant secretion, atelectasis, lethargy, impaired skin barrier function, abnormal skin appearance, neonatal lethality, complete penetrance, shiny skin, small lung, impaired lung alveolus development, pale lung Allele Detail: Gene trapped

  • From Current Category

Cite this (MGI Cat# 3575015, RRID:MGI:3575015)

Source Database: MGI, catalog # 3575015
Genetic Background: involves: 129 * C57BL/6 * ICR
Affected Genes: Mycn
Genomic Alteration: tm1Psk; Tg(Sftpc-cre)1Blh
Availability: Availability unknown check source stock center
Reference: PMID:15716345
Notes: abnormal pulmonary alveolus epithelial cell morphology, abnormal lung morphology, abnormal lung epithelium morphology, decreased type I pneumocyte number, abnormal branching involved in lung morphogenesis, abnormal lung development, neonatal lethality, complete penetrance, decreased type II pneumocyte number Allele Detail: Targeted, Transgenic

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Cite this (MGI Cat# 3718028, RRID:MGI:3718028)

Source Database: MGI, catalog # 3718028
Genetic Background: involves: C57BL/6
Affected Genes: Aldh1a3
Genomic Alteration: tm1Gdu
Availability: Availability unknown check source stock center
Reference: PMID:17207476, PMID:16611695
Notes: neonatal lethality, complete penetrance, abnormal vitreous body morphology, increased total retina thickness, persistent hyperplastic primary vitreous Allele Detail: Targeted

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