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on page 1 showing 20 out of 4,925 results

Cite this (MGI Cat# 5630873, RRID:MGI:5630873)

Source Database: MGI, catalog # 5630873
Genetic Background: C57BL/6N-Atp11a/Wtsi
Affected Genes: Atp11a
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: abnormal Mullerian duct morphology, heterochrony, aorta coarctation, preweaning lethality, complete penetrance, herniated liver, overriding aortic valve, persistent trigeminal artery, abnormal optic stalk morphology, small superior cervical ganglion, abnormal thymus morphology, subcutaneous edema, aphakia, abnormal optic cup morphology, absent olfactory nerve, enlarged liver sinusoidal spaces, thin myocardium compact layer, abnormal nasal cavity morphology, exencephaly, abnormal coronary sinus connection, abnormal olfactory bulb morphology, reduced sympathetic cervical ganglion size, absent ductus venosus valve, trigeminal neuroma, abnormal eye muscle morphology, muscular ventricular septal defect, abnormal olfactory nerve morphology, umbilical vein stenosis, abnormal vertebral artery morphology, abnormal elbow joint morphology, abnormal artery morphology, additional anastomosis between intracranial vertebral arteries, perimembraneous ventricular septal defect, abnormal Meckel's cartilage morphology, abnormal vitelline vein topology, abnormal adenohypophysis morphology, abnormal umbilical vein topology, abnormal carotid artery morphology, abnormal larynx morphology, liver hypoplasia, multiple persisting craniopharyngeal ducts, narrow eye opening, increased rib number, absent pectinate muscle, abnormal eye morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5631554, RRID:MGI:5631554)

Source Database: MGI, catalog # 5631554
Genetic Background: C57BL/6N-Slc5a7/Wtsi
Affected Genes: Slc5a7
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: bicuspid aortic valve, abnormal coronary sinus connection, dilated pancreatic duct, blood in lymph vessels, muscular ventricular septal defect, herniated liver, abnormal small intestine morphology, retrolental blood, preweaning lethality, complete penetrance, abnormal vertebral artery topology, abnormal eye morphology, no abnormal phenotype detected Allele Detail: Targeted

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Cite this (MGI Cat# 5781773, RRID:MGI:5781773)

Source Database: MGI, catalog # 5781773
Genetic Background: B6JTyr;B6N-Kmt5b/Wtsi
Affected Genes: Kmt5b
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: decreased body length, decreased body weight, increased thermal nociceptive threshold Allele Detail: Targeted

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Cite this (MGI Cat# 5883887, RRID:MGI:5883887)

Source Database: MGI, catalog # 5883887
Genetic Background: B6Brd;B6Dnk;B6N-Trim45 Tyr/Wtsi
Affected Genes: Trim45
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: blood in lymph vessels, abnormal forebrain morphology, absent segment of posterior cerebral artery, abnormal ductus venosus valve morphology, abnormal vertebral artery topology, abnormal optic cup morphology, additional anastomosis between intracranial vertebral arteries, abnormal vitelline vein connection, bicuspid aortic valve, abnormal interatrial septum morphology, abnormal Wolffian duct morphology, aphakia, abnormal inferior vena cava morphology, fusion of vertebral arches, subcutaneous edema Allele Detail: Targeted

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Cite this (MGI Cat# 5630945, RRID:MGI:5630945)

Source Database: MGI, catalog # 5630945
Genetic Background: C57BL/6N-Cd300lg/Wtsi
Affected Genes: Cd300lg
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: increased mean corpuscular volume, abnormal pelvic girdle bone morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5705993, RRID:MGI:5705993)

Source Database: MGI, catalog # 5705993
Genetic Background: C57BL/6N-Dynlrb2/Wtsi
Affected Genes: Dynlrb2
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: increased lean body mass, increased fasted circulating glucose level, decreased eosinophil cell number, increased heart weight, increased circulating magnesium level Allele Detail: Targeted

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Cite this (MGI Cat# 5781568, RRID:MGI:5781568)

Source Database: MGI, catalog # 5781568
Genetic Background: C57BL/6N-Ap4e1/Wtsi
Affected Genes: Ap4e1
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: increased lean body mass, abnormal femur morphology, decreased hemoglobin content, increased bone mineral density, abnormal behavior, decreased mean corpuscular hemoglobin Allele Detail: Targeted

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Cite this (MGI Cat# 5824293, RRID:MGI:5824293)

Source Database: MGI, catalog # 5824293
Genetic Background: C57BL/6N-Tm6sf2
Affected Genes: Tm6sf2
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:27013658
Notes: increased triglyceride level, decreased circulating cholesterol level, abnormal circulating apolipoprotein level, abnormal cholesterol homeostasis, increased liver triglyceride level, increased circulating alanine transaminase level, decreased intestinal cholesterol absorption, decreased circulating LDL cholesterol level, decreased circulating HDL cholesterol level, increased circulating triglyceride level, abnormal intestinal lipid absorption, abnormal enterocyte morphology, hepatic steatosis, decreased circulating VLDL triglyceride level Allele Detail: Targeted

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Cite this (MGI Cat# 5544568, RRID:MGI:5544568)

Source Database: MGI, catalog # 5544568
Genetic Background: B6(Cg)-Stac3
Affected Genes: Stac3
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:23626854
Notes: neonatal lethality, complete penetrance, thin diaphragm muscle, decreased fetal weight, cardiovascular system phenotype, abnormal skeletal muscle fiber morphology, increased skeletal muscle fiber diameter, decreased skeletal muscle fiber number, centrally nucleated skeletal muscle fibers, abnormal Z line morphology, abnormal posture, no spontaneous movement, unresponsive to tactile stimuli, abnormal limb posture, abnormal extensor digitorum longus morphology Allele Detail: Targeted

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Cite this (MGI Cat# 5608417, RRID:MGI:5608417)

Source Database: MGI, catalog # 5608417
Genetic Background: C57BL/6N-Il10rb/Wtsi
Affected Genes: Il10rb
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: improved glucose tolerance, decreased B cell number, impaired glucose tolerance Allele Detail: Targeted

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Cite this (MGI Cat# 5630860, RRID:MGI:5630860)

Source Database: MGI, catalog # 5630860
Genetic Background: C57BL/6N-Arhgef38/Wtsi
Affected Genes: Arhgef38
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: increased blood urea nitrogen level, decreased blood urea nitrogen level Allele Detail: Targeted

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Cite this (MGI Cat# 5700912, RRID:MGI:5700912)

Source Database: MGI, catalog # 5700912
Genetic Background: C57BL/6N-Hbs1l/Wtsi
Affected Genes: Hbs1l
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference:
Notes: increased alpha-beta T cell number, decreased total body fat amount, abnormal cornea morphology, corneal opacity, abnormal cranium morphology, increased red blood cell distribution width, decreased eosinophil cell number, increased mean platelet volume, decreased T-helper cell number, abnormal retinal pigmentation, vertebral transformation, increased circulating alkaline phosphatase level, decreased effector memory CD8-positive, alpha-beta T cell number, decreased Ly6C high monocyte number, increased KLRG1+ CD4 alpha beta T cell number, increased gamma-delta T cell number, male infertility, increased rib number, increased mean corpuscular hemoglobin, decreased lean body mass, decreased bone mineral density, decreased monocyte cell number, decreased body length, increased effector memory CD4-positive, alpha-beta T cell number, decreased bone mineral content, abnormal retina morphology, abnormal snout morphology, increased mean corpuscular volume, abnormal lumbar vertebrae morphology, increased circulating total protein level, increased circulating iron level, short snout, increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased NK cell number, increased CD4-positive, alpha beta T cell number, abnormal bone structure, improved glucose tolerance, increased T cell number, increased lean body mass Allele Detail: Targeted

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Cite this (MGI Cat# 6116651, RRID:MGI:6116651)

Source Database: MGI, catalog # 6116651
Genetic Background: involves: C57BL/6N
Affected Genes: Myo10
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:29229982
Notes: kinked tail, persistence of hyaloid vascular system, syndactyly, white spotting, lethality during fetal growth through weaning, incomplete penetrance, belly spot, decreased survivor rate, exencephaly Allele Detail: Targeted

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Cite this (MGI Cat# 5791067, RRID:MGI:5791067)

Source Database: MGI, catalog # 5791067
Genetic Background: involves: C57BL/6 * C57BL/6N
Affected Genes: Spns2
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:24652767, PMID:22664872
Notes: increased bone strength, increased circulating bilirubin level, increased granulocyte number, narrow eye opening, small lens, increased incidence of corneal inflammation, decreased mature B cell number, abnormal iris morphology, corneal opacity, corneal vascularization, abnormal iridocorneal angle, abnormal eye pigmentation, abnormal corneal stroma morphology, decreased leukocyte cell number, decreased circulating glucose level, decreased T cell number, decreased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, decreased CD8-positive, alpha-beta T cell number, decreased B-1 B cell number, decreased B cell number, abnormal humoral immune response, abnormal eye pigmentation, increased CD4-positive, alpha beta T cell number, immune system phenotype, eye opacity, decreased leukocyte cell number, decreased follicular B cell number, decreased IgG1 level, decreased IgG level, decreased CD8-positive, alpha-beta T cell number, abnormal cornea morphology, decreased CD4-positive, alpha beta T cell number, decreased B cell number, abnormal ciliary body morphology, abnormal auditory brainstem response, cataract, increased NK cell number, increased NK T cell number, eyelids fail to open, eye opacity, increased monocyte cell number, increased bone mineral content, absent pinna reflex, abnormal retina morphology, abnormal pupil morphology, increased susceptibility to bacterial infection, microphthalmia Allele Detail: Targeted

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Cite this (MGI Cat# 6115517, RRID:MGI:6115517)

Source Database: MGI, catalog # 6115517
Genetic Background: involves: C57BL/6N
Affected Genes: Sox30
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:29247201
Notes: arrest of spermiogenesis, abnormal spermatogenesis, small testis, male infertility, azoospermia, abnormal spermatid morphology, multinucleated giant male germ cells Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 5790839, RRID:MGI:5790839)

Source Database: MGI, catalog # 5790839
Genetic Background: involves: C57BL/6 * C57BL/6N
Affected Genes: Akap9
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:24652767
Notes: increased circulating alkaline phosphatase level, abnormal pelvic girdle bone morphology, abnormal tooth morphology, decreased B cell number, decreased body weight, decreased circulating HDL cholesterol level, decreased circulating LDL cholesterol level, decreased circulating cholesterol level, decreased circulating serum albumin level, decreased mature B cell number, decreased circulating glucose level, decreased percent body fat/body weight, decreased total body fat amount, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased T cell number, decreased lean body mass, decreased circulating total protein level, lethality, incomplete penetrance, increased oxygen consumption, increased energy expenditure, increased carbon dioxide production Allele Detail: Targeted

  • From Current Category

Cite this (MGI Cat# 6156408, RRID:MGI:6156408)

Source Database: MGI, catalog # 6156408
Genetic Background: C57BL/6-Klhl41
Affected Genes: Klhl41
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: Availability unknown check source stock center
Reference: PMID:28826497
Notes: slow postnatal weight gain, myopathy, neonatal lethality, complete penetrance, abnormal diaphragm morphology, abnormal hindlimb morphology, behavior/neurological phenotype Allele Detail: Targeted

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Cite this (IMSR Cat# KOMP:CSD41509-1a-Wtsi, RRID:IMSR_KOMP:CSD41509-1a-Wtsi)

Source Database: IMSR, catalog # KOMP:CSD41509-1a-Wtsi
Genetic Background:
Affected Genes: Arsg
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: mouse cells
Reference:
Notes: gene symbol note: arylsulfatase G; mutant strain: targeted mutation 1a, Wellcome Trust Sanger Institute

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Cite this (IMSR Cat# KOMP:CSD118793-1a-Wtsi, RRID:IMSR_KOMP:CSD118793-1a-Wtsi)

Source Database: IMSR, catalog # KOMP:CSD118793-1a-Wtsi
Genetic Background:
Affected Genes: Atg9a
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: mouse cells
Reference:
Notes: gene symbol note: autophagy related 9A; mutant strain:

  • From Current Category

Cite this (IMSR Cat# KOMP:CSD76144-1a-Wtsi, RRID:IMSR_KOMP:CSD76144-1a-Wtsi)

Source Database: IMSR, catalog # KOMP:CSD76144-1a-Wtsi
Genetic Background:
Affected Genes: Cptp
Genomic Alteration: tm1a(KOMP)Wtsi
Availability: mouse cells
Reference:
Notes: gene symbol note: ceramide-1-phosphate transfer protein; mutant strain: targeted mutation 1a, Wellcome Trust Sanger Institute

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