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on page 1 showing 20 out of 3,627 results

Cite this (RGD Cat# 2305976, RRID:RGD_2305976)

Source Database: RGD, catalog # 2305976
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This is the strain expresses human Amyloidogenic transthyretin (ATTR) V30M driven by the mouse albumin enhancer/promoter, established at Jichi Medical School. National BioResource Project for the Rat in Japan, Rat Resource & Research Center

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Cite this (RGD Cat# 6907087, RRID:RGD_6907087)

Source Database: RGD, catalog # 6907087
Genetic Background: congenic strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:21205740
Notes: Mammary Neoplasms, Experimental, increased mammary gland tumor incidence A sub congenic strain derived from the progenitor strain WF.WKY-(D5Uwm68-D5Mit4)/Uwm. University of Wisconsin School of Medicine, Madison, Wisconsin

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Cite this (RGD Cat# 12738372, RRID:RGD_12738372)

Source Database: RGD, catalog # 12738372
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: The BDIX.BDIV-D6Mit1-D6Mgh2/Zte congenic strain was produced by crossing BDIX (tumor-susceptible) and BDIV (tumor resistant) and then selecting for strains carrying homozygous segments of the BDIV chromosome on a BDIX background. Institute of Cell Biology (Cancer Research) of Duisburg-Essen University Medical School, Essen, Germany

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Cite this (RGD Cat# 2301081, RRID:RGD_2301081)

Source Database: RGD, catalog # 2301081
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Mmel1. PhysGen, Rat Resource and Research Center, Transposagen

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Cite this (RGD Cat# 737944, RRID:RGD_737944)

Source Database: RGD, catalog # 737944
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Substrain of BN, from Billingham and Silvers 1958, from Harlan Rijnswijk Harlan Rijswijk, Harlan Sprague Dawley, Indianapolis, IN

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Cite this (RGD Cat# 6484560, RRID:RGD_6484560)

Source Database: RGD, catalog # 6484560
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain was produced by injecting ZFNs targeting the sequence CACCACCATCGTGGTtaacaTTTACGAGGATGGTGTCAG into SS/JrHsdMcwi rat embryos. The resulting mutation is a 14-bp deletion in exon 5. PhysGen Knockouts

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Cite this (RGD Cat# 1566439, RRID:RGD_1566439)

Source Database: RGD, catalog # 1566439
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Axenic breeders were obtained at F143 by Taconic in 1984 from the NIH Animal Genetic Resource. Origin of the strain is as follows: to NIH in 1951 from Heston; to Heston in 1949 from Curtis, Columbia University Institute for Cancer Research. To preserve genetic continuity, Taconics F344 foundation colony is maintained in gnotobiotic isolators and the strain is periodically reestablished with breeding pairs from NIH. Taconic

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Cite this (RGD Cat# 737925, RRID:RGD_737925)

Source Database: RGD, catalog # 737925
Genetic Background: inbred
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Substrain of BN, from Billingham and Silvers 1958, to U of Groningen Center for Biology Kerklaan, University of Groningen, The Netherlands

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Cite this (RGD Cat# 2304292, RRID:RGD_2304292)

Source Database: RGD, catalog # 2304292
Genetic Background: transgenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain expresses luciferase ubiquitously driven by the gene trap ROSA 26 promoter established at Jichi Medical School. National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 5686328, RRID:RGD_5686328)

Source Database: RGD, catalog # 5686328
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. PhysGen Knockouts

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Cite this (RGD Cat# 10054453, RRID:RGD_10054453)

Source Database: RGD, catalog # 10054453
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 7-bp deletion in the Sirt3 gene. MCW Gene Editing Rat Resource Center

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Cite this (RGD Cat# 1358258, RRID:RGD_1358258)

Source Database: RGD, catalog # 1358258
Genetic Background: inbred strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:1164921
Notes: abnormal eye pigmentation, abnormal retinal pigmentation, retinal degeneration Developed before 1965 by Sidman from stock obtained from Sorsby of the Royal College of Surgeons, London. Retinal Degeneration Rat Model Resource , Rat Resource and Research Center

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Cite this (RGD Cat# 2301383, RRID:RGD_2301383)

Source Database: RGD, catalog # 2301383
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: SS/Jr and LEW/Crlc were backcrossed for 5 generations, then BC5 rat was mated with LEW/Crlc to produce the desired congenic strain Research Centre-CHUM, Montreal, Quebec, Canada

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Cite this (RGD Cat# 13452382, RRID:RGD_13452382)

Source Database: RGD, catalog # 13452382
Genetic Background: transgenic strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:12620967, PMID:25162006
Notes: Huntington's disease, cognitive inflexibility, decreased dopamine level, impaired limb coordination, neurodegeneration This rat model was developed by injection of SD embryos with construct containing rat huntingtin cDNA fragment with 51 CAG repeats (from HD patient) under control of the native rat huntingtin promoter.

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Cite this (RGD Cat# 13204788, RRID:RGD_13204788)

Source Database: RGD, catalog # 13204788
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: CRISPR/Cas9 system was used to introduce a 60-bp deletion in exon 2 of the rat Pappa2 gene of SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi rat embryos. MCW Gene Editing Rat Resource Center

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Cite this (RGD Cat# 2305979, RRID:RGD_2305979)

Source Database: RGD, catalog # 2305979
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Developed by the DEPOSITOR National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 12798532, RRID:RGD_12798532)

Source Database: RGD, catalog # 12798532
Genetic Background: congenic strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:21257920
Notes: proteinuria, salt-sensitive hypertension SS/JrHsdMcwi were crossed with SS.BN-(D13Rat111-D13Got22)/Mcwi, rats from F1 were intercrossed and genotyped to get the congenic strain Medical College of Wisconsin, Milwaukee, Wisconsin

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Cite this (RGD Cat# 1554306, RRID:RGD_1554306)

Source Database: RGD, catalog # 1554306
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Spontaneous mutant GK rat which were obtained from Japan SLC, Inc. National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 1641876, RRID:RGD_1641876)

Source Database: RGD, catalog # 1641876
Genetic Background: congenic strain
Affected Genes:
Genomic Alteration:
Availability: live
Reference: PMID:17389329
Notes: increased urine glucose level WF RT7.2 allele was introgressed onto the genetic background of BBDP rats and these were crossed with BBDP Department of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada

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Cite this (RGD Cat# 2304293, RRID:RGD_2304293)

Source Database: RGD, catalog # 2304293
Genetic Background: congenic
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: LEC rats which had high X-ray susceptibility were backcrossed to F344. In every generation, highly X-ray susceptible rats were selected with the radiation susceptibility assay National BioResource Project for the Rat in Japan

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