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on page 1 showing 20 out of 58 results

Cite this (NSRRC Cat# 0017, RRID:NSRRC_0017)

Source Database: NSRRC, catalog # 0017
Genetic Background: NIHc/c
Affected Genes: RHO
Genomic Alteration: Transgene: Rhodopsin (RHO) P23H substitution
Availability: Available
Reference: PMID:22247487
Notes: reduced rod and cone function, impaired vision Application: Study of Retinitis Pigmentosa

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Cite this (NSRRC Cat# 0037, RRID:NSRRC_0037)

Source Database: NSRRC, catalog # 0037
Genetic Background: Minnesota Mini
Affected Genes: GGTA1 and CD55
Genomic Alteration: GGTA1 knockout with a transgene for human decay-accelerating factor (CD55) inserted into GGTA1
Availability: Available
Reference:
Notes: Application: Xenotransplantation studies

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Cite this (NSRRC Cat# 0028, RRID:NSRRC_0028)

Source Database: NSRRC, catalog # 0028
Genetic Background: outbred
Affected Genes: CDA
Genomic Alteration: Transgene: Alpha fetoprotein (AFP) promoter driving cytidine deaminase (CDA)
Availability: Available
Reference:
Notes: Tissue specific expression of cytosine deaminase Application: Liver Research

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Cite this (NSRRC Cat# 0025, RRID:NSRRC_0025)

Source Database: NSRRC, catalog # 0025
Genetic Background: outbred
Affected Genes: GGTA1, CD39, CD55, CD59
Genomic Alteration: GGTA1 knockout; with three randomly integrated transgenes: human decay-accelerating factor (CD55); CD39; CD59 and thrombomodulin
Availability: Available
Reference:
Notes: Lack of expression of GGTA1 and expression of CD55, CD39, CD59 and Thrombomodulin Application: Xenotransplantation

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Cite this (NSRRC Cat# 0009, RRID:NSRRC_0009)

Source Database: NSRRC, catalog # 0009
Genetic Background: inbred
Affected Genes: CD55 and GGTA1
Genomic Alteration: GGTA1 knockout and CD55 transgene
Availability: Available
Reference: PMID:7518135
Notes: Application: Xenotransplantation research- has the Cozzi integration of CD55

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Cite this (NSRRC Cat# 0053, RRID:NSRRC_0053)

Source Database: NSRRC, catalog # 0053
Genetic Background: outbred
Affected Genes: PROM1
Genomic Alteration: Transgene: R373C mutation of human PROM1
Availability: Available
Reference:
Notes: Stargard Disease 4 Application: Study of Eye Disorders

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Cite this (NSRRC Cat# 0021, RRID:NSRRC_0021)

Source Database: NSRRC, catalog # 0021
Genetic Background: Yucatan
Affected Genes: NOS3
Genomic Alteration: Transgene: Tie2 promoter driving endothelial Nitrate Oxide Synthase (NOS3)
Availability: Available
Reference: PMID:17080303
Notes: Express endothetial cell specific nitric oxide synthase (NOS3) Application: Cardiovascular, Exercise Physiology

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Cite this (NSRRC Cat# 0048, RRID:NSRRC_0048)

Source Database: NSRRC, catalog # 0048
Genetic Background: outbred
Affected Genes: ELOVL4
Genomic Alteration: Transgene: ELOVL4 Y270X with the enhanced yellow fluorescent protein
Availability: Available
Reference: PMID:21873315
Notes: Stargard Disease 3 Application: Study of Eye Disorders

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Cite this (NSRRC Cat# 0058, RRID:NSRRC_0058)

Source Database: NSRRC, catalog # 0058
Genetic Background: outbred
Affected Genes: C1QTNF5 (CTRP)
Genomic Alteration: Transgene: S163R mutation of pig CTRP (C1QTNF5)
Availability: Available
Reference:
Notes: Age related macular degeneration Application: Study of Eye Disorders

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Cite this (NSRRC Cat# 0015, RRID:NSRRC_0015)

Source Database: NSRRC, catalog # 0015
Genetic Background: inbred
Affected Genes: N/A
Genomic Alteration: wildtype
Availability: Available
Reference: PMID:137560
Notes: homozygous at MHC SLA a/a Application: research in the areas of immune system, and xenotransplantation

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Cite this (NSRRC Cat# 0051, RRID:NSRRC_0051)

Source Database: NSRRC, catalog # 0051
Genetic Background: outbred
Affected Genes: ELOVL4
Genomic Alteration: Transgene: ELOVL4 Y270X with the enhanced yellow fluorescent protein
Availability: Available
Reference: PMID:21873315
Notes: Stargard Disease 3 Application: Study of Eye Disorders

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Cite this (NSRRC Cat# 0030, RRID:NSRRC_0030)

Source Database: NSRRC, catalog # 0030
Genetic Background: Minnesota Mini
Affected Genes: ZP3-CRE-CRE
Genomic Alteration: Transgene: Zona Pecullida 3 (ZP3) promoter driving CRE-eGFP
Availability: Available
Reference:
Notes: Zona pecullida specific express enhanced green fluorescent protein and CRE Application: Cell Tracking

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Cite this (NSRRC Cat# 0008, RRID:NSRRC_0008)

Source Database: NSRRC, catalog # 0008
Genetic Background: inbred
Affected Genes: N/A
Genomic Alteration: wildtype
Availability: Available
Reference: PMID:19434740
Notes: Application: Background for genetic modification,obesity, diabetes, cardiovascular, Polycystic Ovarian Syndrome

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Cite this (NSRRC Cat# 0005, RRID:NSRRC_0005)

Source Database: NSRRC, catalog # 0005
Genetic Background: inbred
Affected Genes: N/A
Genomic Alteration: wildtype
Availability: Available
Reference:
Notes: Application: Immune system ontogeny and regulation, xenotransplantation, xenoimmunotherapy of cancer

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Cite this (NSRRC Cat# 0060, RRID:NSRRC_0060)

Source Database: NSRRC, catalog # 0060
Genetic Background: outbred
Affected Genes: TMPRSS2
Genomic Alteration: TMPRSS2 knockout
Availability: Available
Reference:
Notes: infuenza resistant Application: Immune system

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Cite this (NSRRC Cat# 0038, RRID:NSRRC_0038)

Source Database: NSRRC, catalog # 0038
Genetic Background: outbred
Affected Genes: CD1D
Genomic Alteration: CD1D knockout
Availability: Available
Reference: PMID:25100712
Notes: no natural killer T cells Application: Immunological studies

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Cite this (NSRRC Cat# 0035, RRID:NSRRC_0035)

Source Database: NSRRC, catalog # 0035
Genetic Background: Minnesota Mini
Affected Genes: RAG2
Genomic Alteration: RAG2 Knockout
Availability: Available
Reference: PMID:24799706
Notes: no innate immune system Application: Immunological studies, Xenotransplantation

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Cite this (NSRRC Cat# 0059, RRID:NSRRC_0059)

Source Database: NSRRC, catalog # 0059
Genetic Background: outbred
Affected Genes: Enhanced Yellow Fluorescent Protein
Genomic Alteration: Transgene: male germ cell (STR8) tissue specific expression of enhance yellow fluroescent protein (EYFP)
Availability: Available
Reference: PMID:21826492
Notes: EYFP expression in male germ cells Application: Cell tracking

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Cite this (NSRRC Cat# 0054, RRID:NSRRC_0054)

Source Database: NSRRC, catalog # 0054
Genetic Background: outbred
Affected Genes: PROM1
Genomic Alteration: Transgene: wild type human PROML1
Availability: Available
Reference:
Notes: Stargard Disease 4 Application: Study of Eye Disorders

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Cite this (NSRRC Cat# 0010, RRID:NSRRC_0010)

Source Database: NSRRC, catalog # 0010
Genetic Background: outbred
Affected Genes: N/A
Genomic Alteration: Transgene: CAG promoter driving eGFP
Availability: Available
Reference: PMID:11808633
Notes: express enhanced green fluorescent protein Application: Cell tracking

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