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on page 1 showing 20 out of 886 results

Cite this (RGD Cat# 5688094, RRID:RGD_5688094)

Source Database: RGD, catalog # 5688094
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. PhysGen Knockouts

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Cite this (RGD Cat# 5508369, RRID:RGD_5508369)

Source Database: RGD, catalog # 5508369
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain was produced by injecting ZFNs targeting the sequence CTGATGGGCAGCACCATGgaccccCCGGGGGGTGCA into SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp frameshift deletion in exon 1. PhysGen Knockouts

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Cite this (RGD Cat# 2290067, RRID:RGD_2290067)

Source Database: RGD, catalog # 2290067
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: this Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). PGA

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Cite this (RGD Cat# 2301081, RRID:RGD_2301081)

Source Database: RGD, catalog # 2301081
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Mmel1. PhysGen, Rat Resource and Research Center, Transposagen

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Cite this (RGD Cat# 2306279, RRID:RGD_2306279)

Source Database: RGD, catalog # 2306279
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169).This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Diaph3 gene. PhysGen, Transposagen, Rat Resource & Research Center

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Cite this (RGD Cat# 2314377, RRID:RGD_2314377)

Source Database: RGD, catalog # 2314377
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: A male rat "SRR-Rocket Science" was introduced from American fancy rat colony (Spoiled Ratten Rattery: SRR, in Kansas City, Missouri) to Kyoto University on July 13, 2005. Inbreeding started from F1 progeny of male "SRR-Rocket Science" and a female PVG/Seac. Homozygous rats for grey mutation were selected for inbreeding. National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 10054453, RRID:RGD_10054453)

Source Database: RGD, catalog # 10054453
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Sirt3 gene of SS/JrHsdMcwi rat embryos. The resulting mutation is a 7-bp deletion in the Sirt3 gene. MCW Gene Editing Rat Resource Center

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Cite this (RGD Cat# 14695085, RRID:RGD_14695085)

Source Database: RGD, catalog # 14695085
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: muscular dystrophy, The use of zinc finger nuclease technology (ZFN) to knockin a luciferase reporter directly downstream of MuRF1 (Trim63) coding sequences in rats,leaving endogenous MuRF1 gene expression intact and bicistro-nically linking it to the inserted reporter through a hepatitis CIRES (HCV-IRES). The resulting knockin rat line, MuRF1-hiLUCs, has reporter characteristics that are fully reflective ofendogenous MuRF1 gene expression, can be used as a universalbiomarker of skeletal muscle atrophyin vivo, and has abioluminescent readout compatible with whole animal imagingmodalities. Rat Resource and Research Center

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Cite this (RGD Cat# 13204788, RRID:RGD_13204788)

Source Database: RGD, catalog # 13204788
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: CRISPR/Cas9 system was used to introduce a 60-bp deletion in exon 2 of the rat Pappa2 gene of SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi rat embryos. MCW Gene Editing Rat Resource Center

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Cite this (RGD Cat# 12879424, RRID:RGD_12879424)

Source Database: RGD, catalog # 12879424
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain was established at Kyoto University. ChR90/EGFP fusion gene sequence under CAG promoter is knock-in at the Rosa26 locus. Background strain: Long-Evans strain (charles river). COP4*: Stigeoclonium helveticum-derived channelrhodopsin (Chronos, ChR90) National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 9685754, RRID:RGD_9685754)

Source Database: RGD, catalog # 9685754
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain shows severe combined immunodeficiency caused by a zinc finger nuclease induced 653-bp deletion in Il2rg gene of TM/Kyo embryo. The rats grow normally under SPF condition. National BioResource Project for the Rat in Japan

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Cite this (RGD Cat# 13792803, RRID:RGD_13792803)

Source Database: RGD, catalog # 13792803
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This allele was made by CRISPR/Cas9 system. The resulting mutation is a 10-bp insertion in Exon 2 of the P2rx7 gene.

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Cite this (RGD Cat# 5688119, RRID:RGD_5688119)

Source Database: RGD, catalog # 5688119
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. PhysGen Knockouts

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Cite this (RGD Cat# 1581634, RRID:RGD_1581634)

Source Database: RGD, catalog # 1581634
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: Male founders are injected with ENU (N-ethyl-N-nitrosourea) and harem bred to females. The pups are genetically screened using the TILLING assay (an enzyme-based heteroduplex cleavage assay) as well as nucleotide sequencing to identify and characterize target genes possessing ENU-induced mutations. C249S mutation is generated from the codon change TGT/AGT of rat Adora2a. PhysGen

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Cite this (RGD Cat# 5688051, RRID:RGD_5688051)

Source Database: RGD, catalog # 5688051
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. PhysGen Knockouts

  • From Current Category

Cite this (RGD Cat# 5686666, RRID:RGD_5686666)

Source Database: RGD, catalog # 5686666
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: ZFN mutant founders were backcrossed with SS/JrHsdMcwi to get heterozygous offsprings which were intercrossed and offsprings maintained as homozygous and heterozygous breeders. PhysGen Knockouts

  • From Current Category

Cite this (RGD Cat# 11553873, RRID:RGD_11553873)

Source Database: RGD, catalog # 11553873
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: CRISPR/Cas9 system was used to introduce a mutation in the Fmr1 gene of Crl:LE rat embryos. The resulting mutation is a 2-bp insertion in exon 7 of the Fmr1 gene. MCW Gene Editing Rat Resource Center

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Cite this (RGD Cat# 2299124, RRID:RGD_2299124)

Source Database: RGD, catalog # 2299124
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 4th intron of the Ubqln4 gene. PhysGen, Transposagen, Rat Resource and Research Center

  • From Current Category

Cite this (RGD Cat# 5144103, RRID:RGD_5144103)

Source Database: RGD, catalog # 5144103
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: This strain was produced by injecting ZFNs targeting the sequence TGCATCCCCAGCCTGTGGgcctgcGACGGGGACCGGGAC into SS/JrHsdMcwi rat embryos. The resulting mutation is a 13-bp frameshift deletion in exon 4. PhysGen Knockouts

  • From Current Category

Cite this (RGD Cat# 2302652, RRID:RGD_2302652)

Source Database: RGD, catalog # 2302652
Genetic Background: mutant
Affected Genes:
Genomic Alteration:
Availability: live
Reference:
Notes: These Sleeping Beauty mutants were derived by crossing F344-TgTn(T2/Bart3)2Ceb (RGD:2290163) and F344-Tg(PGK2-sb11)Ceb (RGD:2290169). This mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 2nd intron of the Pde4d gene. PhysGen, Transposagen, Rat Resource and Research Center

  • From Current Category

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