URL: http://toppgene.cchmc.org/
Proper Citation: ToppGene Suite (RRID:SCR_005726)
Description: ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis.
Synonyms: ToppGene
Resource Type: portal, database, data or information resource, data analysis service, analysis service resource, service resource, production service resource, resource
Defining Citation: PMID:19465376
Keywords: gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list
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