URL: http://www.wormbase.org/db/get?name=WBStrain00040824
Proper Citation: RRID:WB-STRAIN:WBStrain00040824
Description: Caenorhabditis elegans with name hif-1(ia4) V. from WB.
Species: Caenorhabditis elegans
Synonyms: hif-1(ia4) V.
Notes: Healthy and fertile in standard lab conditions, but unable to adapt to 1% oxygen. When hif-1(+) animals are incubated in1% oxygen, >94% will complete embryogenesis and larval development. In contrast, hif-1(ia4) mutants exhibit 66% embryonic lethality and 9% larval lethality in 1% oxygen. The requirement of hif-1 is alleviated if the oxygen level is increased to 2%. The ia4 mutation is a 1231 bp deletion of the second, third, and fourth exons, which encode much of the helix-loop-helix and PAS domains. Analysis of ESTs suggests that there are at least 4 alternatively spliced hif-1 transcripts. The ia4 deletion introduces a frameshift and a premature stop in the three longest forms.|"Made_by: Jiang/Powell-Coffman"|"Reference WBPaper00059755 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype hif-1(ia4), RE666 ire-1(v33), xbp-1(tm2482)"
Affected Gene: WBGene00001851(hif-1)
Expand AllWe found {{ ctrl2.mentions.total_count }} mentions in open access literature.
We have not found any literature mentions for this resource.
We are searching literature mentions for this resource.
Most recent articles:
{{ mention._source.dc.creators[0].familyName }} {{ mention._source.dc.creators[0].initials }}, et al. ({{ mention._source.dc.publicationYear }}) {{ mention._source.dc.title }} {{ mention._source.dc.publishers[0].name }}, {{ mention._source.dc.publishers[0].volume }}({{ mention._source.dc.publishers[0].issue }}), {{ mention._source.dc.publishers[0].pagination }}. (PMID:{{ mention._id.replace('PMID:', '') }})
Check
for all resource mentions.
A list of researchers who have used the resource and an author search tool
Find mentions based on location
{{ ctrl2.mentions.errors.location }}
A list of researchers who have used the resource and an author search tool. This is available for resources that have literature mentions.
No rating or validation information has been found for ZG31.
No alerts have been found for ZG31.
Source: Integrated Animals
Source Database: WormBase (WB)