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Organism Information

URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=11041106

Proper Citation: RRID:RGD_11041106

Description: Rattus norvegicus with name LE-Tg(Pvalb-tTA)15Hio from RGD.

Species: Rattus norvegicus

Notes: background strain #65306; Long-Evans rat #65288; Iar:Long-Evans #65289; Transgene #65306; (1) Parvalbumin (PV) promoter #65306; mouse derived (MGI:97821). PV is calcium-binding protein. (2) tetracycline transactivator (tTA) #65306; Fusion protein of tetracycline repressor (Escherichia coli-derived) and VP16 (Herpes simplex virus-derived). In the absence of Doxycycline (Dox), tTA binds to tetracycline-responsive element (TRE) and expression of TRE-controlled genes can be induced. Vector #65306; pBlueScript (Stratagene), pBACe3.6 (CHORI) National BioResource Project for the Rat in Japan

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Data and Source Information

Source: Integrated Animals

Source Database: Rat Genome Database (RGD)