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Organism Name
C57BL/6N-Rnf10tm1b(KOMP)Wtsi/JMmucd
RRID:MMRRC_049477-UCD RRID Copied  
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RRID:MMRRC_049477-UCD
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=49477

Proper Citation: RRID:MMRRC_049477-UCD

Description: Mus musculus with name C57BL/6N-Rnf10tm1b(KOMP)Wtsi/JMmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP

Phenotype: decreased bone mineral density [MP:0000063]| decreased circulating HDL cholesterol level [MP:0000186]| enlarged heart [MP:0000274]| thin ventricular wall [MP:0000280]| abnormal tibia morphology [MP:0000558]| abnormal spleen morphology [MP:0000689]| convulsive seizures [MP:0000947]| decreased body length [MP:0001258]| abnormal lens morphology [MP:0001303]| hyperactivity [MP:0001399]| jumpy [MP:0001401]| hypoactivity [MP:0001402]| limb grasping [MP:0001513]| abnormal digit morphology [MP:0002110]| increased vertical activity [MP:0002574]| decreased mean corpuscular volume [MP:0002591]| decreased circulating triglyceride level [MP:0002644]| short tibia [MP:0002764]| decreased hemoglobin content [MP:0002874]| decreased circulating alkaline phosphatase level [MP:0002966]| increased circulating chloride level [MP:0003019]| straub tail [MP:0003382]| abnormal bone structure [MP:0003795]| increased lean body mass [MP:0003960]| decreased lean body mass [MP:0003961]| abnormal behavior [MP:0004924]| decreased spleen weight [MP:0004953]| decreased circulating cholesterol level [MP:0005179]| improved glucose tolerance [MP:0005292]| decreased heart rate [MP:0005333]| decreased circulating serum albumin level [MP:0005419]| decreased cornea thickness [MP:0005543]| increased circulating creatinine level [MP:0005553]| decreased circulating creatinine level [MP:0005554]| decreased circulating glucose level [MP:0005560]| decreased circulating total protein level [MP:0005567]| increased cardiac muscle contractility [MP:0005599]| increased circulating sodium level [MP:0005633]| decreased mean corpuscular hemoglobin concentration [MP:0005642]| decreased NK T cell number [MP:0008040]| increased NK cell number [MP:0008044]| increased marginal zone B cell number [MP:0008181]| decreased prepulse inhibition [MP:0009142]| decreased total body fat amount [MP:0010025]| decreased grip strength [MP:0010053]| abnormal retinal blood vessel morphology [MP:0010097]| increased bone mineral content [MP:0010123]| decreased bone mineral content [MP:0010124]| preweaning lethality [MP:0011110]| incomplete penetrance [MP:0011275]| abnormal behavioral response to light [MP:0011396]| abnormal sleep behavior [MP:0011965]| decreased total retina thickness [MP:0011967]| increased or absent threshold for auditory brainstem response [MP:0013678]

Affected Gene: Rnf10

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)