URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=48798
Proper Citation: RRID:MMRRC_048798-UCD
Description: Mus musculus with name C57BL/6N-Nfkb1tm1a(KOMP)Wtsi/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: KOMP
Phenotype: increased leukocyte cell number [MP:0000218]| lymphoid hyperplasia [MP:0000688]| abnormal skin condition [MP:0001191]| abnormal cornea morphology [MP:0001312]| increased circulating free fatty acid level [MP:0001554]| decreased IgA level [MP:0001807]| increased thermal nociceptive threshold [MP:0001973]| increased susceptibility to bacterial infection [MP:0002412]| increased circulating alkaline phosphatase level [MP:0002968]| decreased lean body mass [MP:0003961]| decreased thermal nociceptive threshold [MP:0003998]| decreased regulatory T cell number [MP:0004974]| decreased circulating sodium level [MP:0005634]| decreased mean corpuscular hemoglobin concentration [MP:0005642]| decreased NK cell number [MP:0008045]| decreased IgG1 level [MP:0008495]| decreased circulating amylase level [MP:0008805]| decreased respiratory quotient [MP:0010379]
Affected Gene: Nfkb1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)