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Organism Name
B6;129-Syn2tm1Pggd Syn3tm1Pggd Syn1tm1Pggd/Mmjax
RRID:MMRRC_041434-JAX RRID Copied  
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RRID:MMRRC_041434-JAX
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41434

Proper Citation: RRID:MMRRC_041434-JAX

Description: Mus musculus with name B6;129-Syn2tm1Pggd Syn3tm1Pggd Syn1tm1Pggd/Mmjax from MMRRC.

Species: Mus musculus

Notes: Research areas: Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:

Phenotype: increased aggression towards mice [MP:0001353]| abnormal social investigation [MP:0001360]| abnormal seizure response to electrical stimulation [MP:0001650]| abnormal emotion/affect behavior [MP:0002572]| abnormal excitatory postsynaptic potential [MP:0002912]| increased synaptic depression [MP:0002916]| delayed CNS synapse formation [MP:0002924]| impaired social transmission of food preference [MP:0002969]| tonic-clonic seizures [MP:0003997]| abnormal synaptic vesicle clustering [MP:0004793]| abnormal brain wave pattern [MP:0004994]| abnormal CNS synapse formation [MP:0004996]| abnormal neurotransmitter secretion [MP:0005445]| environmentally induced seizures [MP:0009358]| abnormal hippocampus pyramidal cell morphology [MP:0009940]| abnormal social investigation [MP:0001360]| abnormal excitatory postsynaptic currents [MP:0002910]| increased synaptic depression [MP:0002916]| abnormal inhibitory postsynaptic currents [MP:0002945]| delayed axon extension [MP:0002946]| impaired social transmission of food preference [MP:0002969]| decreased aggression towards mice [MP:0003863]| tonic-clonic seizures [MP:0003997]| abnormal brain wave pattern [MP:0004994]| environmentally induced seizures [MP:0009358]| increased aggression towards mice [MP:0001353]| abnormal social investigation [MP:0001360]| increased grooming behavior [MP:0001441]| seizures [MP:0002064]| abnormal brain morphology [MP:0002152]| decreased brain weight [MP:0002175]| abnormal CNS synaptic transmission [MP:0002206]| abnormal emotion/affect behavior [MP:0002572]| abnormal short term object recognition memory [MP:0002800]| abnormal neuron morphology [MP:0002882]| abnormal excitatory postsynaptic potential [MP:0002912]| decreased synaptic depression [MP:0002917]| delayed CNS synapse formation [MP:0002924]| tonic-clonic seizures [MP:0003997]| abnormal miniature excitatory postsynaptic currents [MP:0004753]| abnormal synaptic vesicle number [MP:0004792]| abnormal brain wave pattern [MP:0004994]| abnormal CNS synapse formation [MP:0004996]| environmentally induced seizures [MP:0009358]| abnormal hippocampus physiology [MP:0012006]

Affected Gene: Syn1||Syn2||Syn3|

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)