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Organism Name
B6.Cg-Tcratm1Mom Tg(TcrLCMV)327Sdz/TacMmjax
RRID:MMRRC_037394-JAX RRID Copied  
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RRID:MMRRC_037394-JAX
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37394

Proper Citation: RRID:MMRRC_037394-JAX

Description: Mus musculus with name B6.Cg-Tcratm1Mom Tg(TcrLCMV)327Sdz/TacMmjax from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection:

Phenotype: abnormal large intestine morphology [MP:0000489]| crypts of Lieberkuhn abscesses [MP:0000491]| rectal prolapse [MP:0000493]| intestinal ulcer [MP:0000512]| decreased thymocyte number [MP:0000715]| chronic diarrhea [MP:0001665]| decreased IgG level [MP:0001805]| thymus hypoplasia [MP:0001823]| arrested T cell differentiation [MP:0001825]| increased inflammatory response [MP:0001846]| premature death [MP:0002083]| abnormal respiratory system morphology [MP:0002132]| abnormal T cell differentiation [MP:0002145]| abnormal double-negative T cell morphology [MP:0002407]| abnormal double-positive T cell morphology [MP:0002408]| increased susceptibility to bacterial infection [MP:0002412]| colitis [MP:0002816]| abnormal intestinal goblet cell morphology [MP:0003449]| impaired macrophage chemotaxis [MP:0003799]| myositis [MP:0004510]| abnormal negative T cell selection [MP:0004918]| abnormal positive T cell selection [MP:0004919]| skin inflammation [MP:0004947]| abnormal response to infection [MP:0005025]| increased double-negative T cell number [MP:0005090]| decreased double-positive T cell number [MP:0005092]| decreased T cell proliferation [MP:0005095]| abnormal response to transplant [MP:0005671]| abnormal NK T cell morphology [MP:0008036]| abnormal T cell morphology [MP:0008037]| abnormal NK T cell physiology [MP:0008042]| absent T cells [MP:0008070]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| decreased CD8-positive [MP:0008348]| alpha-beta T cell number [MP:0008350]| absent gamma-delta T cells [MP:0008353]| increased gamma-delta intraepithelial T cell number [MP:0008466]| increased mature gamma-delta T cell number [MP:0008699]| enlarged mesenteric lymph nodes [MP:0008700]| increased interleukin-4 secretion [MP:0008719]| decreased interleukin-4 secretion [MP:0008895]| decreased cell proliferation [MP:0000352]| decreased thymocyte number [MP:0000715]| hyperglycemia [MP:0001559]| increased urine glucose level [MP:0001759]| thymus hypoplasia [MP:0001823]| autoimmune response [MP:0001844]| increased T cell derived lymphoma incidence [MP:0002024]| premature death [MP:0002083]| abnormal T cell differentiation [MP:0002145]| increased circulating ketone body level [MP:0002575]| ketoaciduria [MP:0002893]| abnormal cytokine secretion [MP:0003009]| insulitis [MP:0004031]| abnormal T cell selection [MP:0004917]| abnormal positive T cell selection [MP:0004919]| abnormal B cell selection [MP:0004942]| abnormal CD8-positive [MP:0005010]| alpha beta T cell morphology [MP:0005079]| decreased cytotoxic T cell cytolysis [MP:0005090]| increased double-negative T cell number [MP:0005092]| decreased double-positive T cell number [MP:0005094]| abnormal T cell proliferation [MP:0005095]| decreased T cell proliferation [MP:0005150]| cachexia [MP:0005580]| periinsulitis [MP:0005671]| abnormal response to transplant [MP:0006043]| decreased apoptosis [MP:0006387]| abnormal T cell number [MP:0008037]| abnormal T cell morphology [MP:0008075]| decreased CD4-positive [MP:0008079]| alpha beta T cell number [MP:0008747]| decreased CD8-positive [MP:0008874]| alpha-beta T cell number [MP:0009174]| abnormal T cell anergy [MP:0009335]

Affected Gene: Tcra|||Tcrb|Tcra

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)