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Organism Name
NOD.Cg-Cd40tm1Kik H2h4/HbmMmmh
RRID:MMRRC_037352-MU RRID Copied  
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RRID:MMRRC_037352-MU
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=37352

Proper Citation: RRID:MMRRC_037352-MU

Description: Mus musculus with name NOD.Cg-Cd40tm1Kik H2h4/HbmMmmh from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: Mullen

Phenotype: decreased bone mineral density [MP:0000063]| decreased neutrophil cell number [MP:0000222]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal humoral immune response [MP:0001800]| decreased IgA level [MP:0001807]| no abnormal phenotype detected [MP:0002169]| abnormal thymus medulla morphology [MP:0002375]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| decreased IgE level [MP:0002492]| glomerulonephritis [MP:0002743]| increased urine protein level [MP:0002962]| increased anti-double stranded DNA antibody level [MP:0004762]| abnormal class switch recombination [MP:0004816]| decreased B cell number [MP:0005017]| decreased susceptibility to type II hypersensitivity reaction [MP:0005612]| decreased cerebral infarction size [MP:0006058]| increased follicular B cell number [MP:0008173]| absent germinal center B cells [MP:0008179]| increased marginal zone B cell number [MP:0008181]| increased transitional stage B cell number [MP:0008189]| abnormal B cell activation [MP:0008217]| absent spleen germinal center [MP:0008474]| decreased IgG1 level [MP:0008495]| decreased IgG2a level [MP:0008496]| decreased IgG2b level [MP:0008497]| decreased IgG3 level [MP:0008498]| abnormal thymus epithelium morphology [MP:0009544]| decreased platelet aggregation [MP:0009549]| decreased trabecular bone mass [MP:0010873]| decreased compact bone mass [MP:0010962]| renal glomerular immunoglobulin deposits [MP:0020519]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]

Affected Gene: Cd40

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)