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Organism Name
B6;129S5-Il22tm1.1Lex/Mmucd
RRID:MMRRC_036745-UCD RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36745

Proper Citation: RRID:MMRRC_036745-UCD

Description: Mus musculus with name B6;129S5-Il22tm1.1Lex/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Cell Biology, Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Genentech

Phenotype: abnormal colon morphology [MP:0000495]| thick dermal layer [MP:0001245]| mixed cellular infiltration to dermis [MP:0001246]| decreased body weight [MP:0001262]| multifocal hepatic necrosis [MP:0001655]| ear inflammation [MP:0001849]| lung inflammation [MP:0001861]| acanthosis [MP:0001874]| colitis [MP:0002816]| abnormal cytokine secretion [MP:0003009]| abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842]| increased susceptibility to fungal infection [MP:0005399]| decreased circulating tumor necrosis factor level [MP:0008554]| increased circulating interleukin-17 level [MP:0008614]| decreased circulating interleukin-12 level [MP:0008618]| decreased circulating interleukin-1 alpha level [MP:0008639]| decreased circulating interleukin-12b level [MP:0008648]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009788]| abnormal circulating cytokine level [MP:0010210]

Affected Gene: Il22

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)