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Organism Name
B6N;129S6-Raf1tm1.1Bgn/Mmucd
RRID:MMRRC_036521-UCD RRID Copied  
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RRID:MMRRC_036521-UCD
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=36521

Proper Citation: RRID:MMRRC_036521-UCD

Description: Mus musculus with name B6N;129S6-Raf1tm1.1Bgn/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Developmental Biology, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection:

Phenotype: increased leukocyte cell number [MP:0000218]| increased neutrophil cell number [MP:0000219]| increased monocyte cell number [MP:0000220]| increased cranium width [MP:0000441]| flattened snout [MP:0000447]| enlarged spleen [MP:0000691]| decreased body length [MP:0001258]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| ocular hypertelorism [MP:0001300]| abnormal cardiovascular system physiology [MP:0001544]| cardiac hypertrophy [MP:0001625]| dilated cardiomyopathy [MP:0002795]| increased heart weight [MP:0002833]| thick ventricular wall [MP:0002953]| cardiac fibrosis [MP:0003141]| increased cardiac output [MP:0003394]| abnormal facial morphology [MP:0003743]| increased left ventricle systolic pressure [MP:0003820]| abnormal heart left ventricle morphology [MP:0003921]| increased response of heart to induced stress [MP:0004485]| enlarged myocardial fiber [MP:0004564]| decreased cardiac muscle contractility [MP:0005140]| increased cardiac muscle contractility [MP:0005599]| cardiac interstitial fibrosis [MP:0005608]| abnormal common myeloid progenitor cell morphology [MP:0006410]| decreased cranium height [MP:0008525]| enlarged heart right atrium [MP:0008727]| increased heart ventricle size [MP:0008772]| increased sensitivity to induced morbidity/mortality [MP:0009763]| increased heart left ventricle size [MP:0010579]| thick interventricular septum [MP:0010724]| abnormal heart left ventricle pressure [MP:0010754]| increased cardiac stroke volume [MP:0011951]

Affected Gene: Raf1

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)