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Organism Name
C.129S5-Il22tm1.1Lex/Mmucd
RRID:MMRRC_032402-UCD RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=32402

Proper Citation: RRID:MMRRC_032402-UCD

Description: Mus musculus with name C.129S5-Il22tm1.1Lex/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: Genentech

Phenotype: abnormal colon morphology [MP:0000495]| thick dermal layer [MP:0001245]| mixed cellular infiltration to dermis [MP:0001246]| decreased body weight [MP:0001262]| multifocal hepatic necrosis [MP:0001655]| ear inflammation [MP:0001849]| lung inflammation [MP:0001861]| acanthosis [MP:0001874]| colitis [MP:0002816]| abnormal cytokine secretion [MP:0003009]| abnormal large intestine crypts of Lieberkuhn morphology [MP:0004842]| increased susceptibility to fungal infection [MP:0005399]| decreased circulating tumor necrosis factor level [MP:0008554]| increased circulating interleukin-17 level [MP:0008614]| decreased circulating interleukin-12 level [MP:0008618]| decreased circulating interleukin-1 alpha level [MP:0008639]| decreased circulating interleukin-12b level [MP:0008648]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009788]| abnormal circulating cytokine level [MP:0010210]

Affected Gene: Il22

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)