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Organism Name
B6.129S2-Ifnar1tm1Agt/Mmjax
RRID:MMRRC_032045-JAX RRID Copied  
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RRID:MMRRC_032045-JAX
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=32045

Proper Citation: RRID:MMRRC_032045-JAX

Description: Mus musculus with name B6.129S2-Ifnar1tm1Agt/Mmjax from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection:

Phenotype: decreased bone mineral density [MP:0000063]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| enlarged lymph nodes [MP:0000702]| abnormal skin condition [MP:0001191]| anemia [MP:0001577]| postnatal growth retardation [MP:0001732]| altered susceptibility to infection [MP:0001793]| decreased IgG level [MP:0001805]| abnormal inflammatory response [MP:0001845]| salivary gland inflammation [MP:0001870]| small lymph nodes [MP:0002217]| abnormal dendritic cell physiology [MP:0002376]| abnormal lymphopoiesis [MP:0002401]| decreased susceptibility to viral infection [MP:0002410]| increased susceptibility to viral infection [MP:0002418]| abnormal macrophage morphology [MP:0002446]| abnormal immunoglobulin level [MP:0002490]| increased IgG level [MP:0002493]| increased IgM level [MP:0002494]| increased IgA level [MP:0002495]| glomerulonephritis [MP:0002743]| joint inflammation [MP:0002933]| increased urine protein level [MP:0002962]| abnormal cytokine secretion [MP:0003009]| abnormal leukocyte migration [MP:0003156]| rheumatoid arthritis [MP:0003561]| increased tumor growth/size [MP:0003721]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| decreased fetal size [MP:0004200]| abnormal CD8-positive [MP:0004392]| alpha-beta T cell physiology [MP:0004762]| increased anti-double stranded DNA antibody level [MP:0004794]| increased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-nuclear antigen antibody level [MP:0004801]| increased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to systemic lupus erythematosus [MP:0004952]| increased spleen weight [MP:0004982]| abnormal osteoclast morphology [MP:0005025]| abnormal response to infection [MP:0005027]| increased susceptibility to parasitic infection [MP:0005070]| impaired natural killer cell mediated cytotoxicity [MP:0005542]| corneal vascularization [MP:0008476]| increased spleen red pulp amount [MP:0008501]| increased IgG2b level [MP:0008502]| increased IgG3 level [MP:0008553]| increased circulating tumor necrosis factor level [MP:0008559]| abnormal interferon-gamma secretion [MP:0008561]| decreased tumor necrosis factor secretion [MP:0008563]| decreased interferon-alpha secretion [MP:0008565]| decreased interferon-beta secretion [MP:0008593]| increased circulating interleukin-10 level [MP:0008617]| increased circulating interleukin-12 level [MP:0008635]| increased circulating interleukin-18 level [MP:0008706]| decreased interleukin-6 secretion [MP:0008713]| abnormal cytokine level [MP:0009642]| abnormal blood homeostasis [MP:0009788]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009790]| decreased susceptibility to viral infection induced morbidity/mortality [MP:0009791]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010750]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal NK cell physiology [MP:0011089]

Affected Gene: Ifnar1

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)