URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=31656
Proper Citation: RRID:MMRRC_031656-UCD
Description: Mus musculus with name B6N.129S5(B6)-Vsirtm1Lex/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: Genentech
Phenotype: hepatic necrosis [MP:0001654]| abnormal T cell activation [MP:0001828]| increased inflammatory response [MP:0001846]| increased IgM level [MP:0002494]| increased IgA level [MP:0002495]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| increased tumor necrosis factor secretion [MP:0008560]| increased interferon-gamma secretion [MP:0008566]| increased interleukin-17 secretion [MP:0008681]| pancreas necrosis [MP:0009148]| pulmonary necrosis [MP:0010857]
Affected Gene: Vsir
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)