URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30499
Proper Citation: RRID:MMRRC_030499-UCD
Description: Mus musculus with name C57BL/6J-Map3k8m1Btlr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Immunology and Inflammation; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix
Phenotype: abnormal response to infection [MP:0005025]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal tumor necrosis factor secretion [MP:0008556]| decreased tumor necrosis factor secretion [MP:0008561]| decreased interferon-alpha secretion [MP:0008563]| decreased interferon-beta secretion [MP:0008565]| decreased interleukin-1 beta secretion [MP:0008658]| increased interleukin-12b secretion [MP:0008669]| decreased interleukin-6 secretion [MP:0008706]| prenatal lethality [MP:0011101]
Affected Gene: Map3k8
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)