URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30490
Proper Citation: RRID:MMRRC_030490-MU
Description: Mus musculus with name B6;129-Ireb2tm1Roua/Mmmh from MMRRC.
Species: Mus musculus
Notes: Research areas: Hematology, Metabolism, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: kyphosis [MP:0000160]| decreased hematocrit [MP:0000208]| tremors [MP:0000745]| abnormal thalamus morphology [MP:0000832]| abnormal cerebellum morphology [MP:0000849]| Purkinje cell degeneration [MP:0000876]| decreased Purkinje cell number [MP:0000880]| abnormal corpora quadrigemina morphology [MP:0000899]| abnormal locomotor behavior [MP:0001392]| ataxia [MP:0001393]| abnormal gait [MP:0001406]| abnormal posture [MP:0001504]| impaired balance [MP:0001525]| decreased mean corpuscular volume [MP:0002591]| microcytosis [MP:0002813]| decreased hemoglobin content [MP:0002874]| abnormal vestibular system physiology [MP:0004742]| bradykinesia [MP:0005156]| decreased mean corpuscular hemoglobin [MP:0005562]| abnormal iron homeostasis [MP:0005637]| decreased mean corpuscular hemoglobin concentration [MP:0005642]| decreased liver iron level [MP:0008743]| increased liver iron level [MP:0008807]| decreased spleen iron level [MP:0008808]| increased circulating iron level [MP:0008810]| decreased grip strength [MP:0010053]| increased circulating ferritin level [MP:0011890]| decreased circulating unsaturated transferrin level [MP:0011897]| increased brain iron level [MP:0020365]| increased intestinal iron level [MP:0020369]
Affected Gene: Ireb2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)