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Organism Name
NFR.B-Vps54wr/Mmmh
RRID:MMRRC_030340-MU RRID Copied  
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RRID:MMRRC_030340-MU
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30340

Proper Citation: RRID:MMRRC_030340-MU

Description: Mus musculus with name NFR.B-Vps54wr/Mmmh from MMRRC.

Species: Mus musculus

Notes: Research areas: Neurobiology; Mutation Type: Spontaneous Mutation ; Collection:

Phenotype: abnormal cell morphology [MP:0000358]| abnormal hepatocyte morphology [MP:0000607]| tremors [MP:0000745]| muscle weakness [MP:0000747]| progressive muscle weakness [MP:0000748]| forelimb paralysis [MP:0000756]| abnormal myelination [MP:0000920]| demyelination [MP:0000921]| abnormal motor neuron morphology [MP:0000937]| motor neuron degeneration [MP:0000938]| abnormal spinal nerve morphology [MP:0001077]| decreased body weight [MP:0001262]| abnormal gait [MP:0001406]| abnormal posture [MP:0001504]| limb grasping [MP:0001513]| abnormal grip strength [MP:0001515]| infertility [MP:0001924]| abnormal gametogenesis [MP:0001929]| premature death [MP:0002083]| abnormal muscle physiology [MP:0002106]| abnormal astrocyte morphology [MP:0002182]| gliosis [MP:0002183]| abnormal CNS synaptic transmission [MP:0002206]| muscular atrophy [MP:0002269]| abnormal sciatic nerve morphology [MP:0002651]| asthenozoospermia [MP:0002675]| globozoospermia [MP:0002686]| oligozoospermia [MP:0002687]| abnormal inhibitory postsynaptic currents [MP:0002945]| abnormal skeletal muscle fiber morphology [MP:0003084]| abnormal GABAergic neuron morphology [MP:0003245]| decreased circulating estrogen level [MP:0003371]| abnormal nervous system morphology [MP:0003632]| abnormal nervous system physiology [MP:0003633]| abnormal nucleotide metabolism [MP:0003806]| abnormal GABA-mediated receptor currents [MP:0004008]| abnormal axonal transport [MP:0004768]| decreased testis weight [MP:0004852]| abnormal lysosome morphology [MP:0005058]| upturned snout [MP:0006411]| abnormal synaptic bouton morphology [MP:0008571]| abnormal miniature inhibitory postsynaptic currents [MP:0009435]| decreased grip strength [MP:0010053]| abnormal GABAergic neuron physiology [MP:0011987]| increased microglial cell activation [MP:0020448]| facial muscle atrophy [MP:0030140]

Affected Gene: Vps54

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)