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Organism Name
C57BL/6J-Card11m1Btlr/Mmucd
RRID:MMRRC_030114-UCD RRID Copied  
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RRID:MMRRC_030114-UCD
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=30114

Proper Citation: RRID:MMRRC_030114-UCD

Description: Mus musculus with name C57BL/6J-Card11m1Btlr/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Cell Biology, Developmental Biology, Diabetes, Immunology and Inflammation, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix

Phenotype: dermatitis [MP:0001194]| decreased IgM level [MP:0001806]| abnormal T cell activation [MP:0001828]| abnormal double-negative T cell morphology [MP:0002407]| decreased immunoglobulin level [MP:0002460]| abnormal cytokine secretion [MP:0003009]| decreased regulatory T cell number [MP:0004974]| decreased B-1 B cell number [MP:0004978]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased B cell proliferation [MP:0005093]| decreased T cell proliferation [MP:0005095]| decreased NK T cell number [MP:0008040]| decreased NK cell number [MP:0008045]| decreased memory T cell number [MP:0008050]| decreased mature B cell number [MP:0008211]| decreased gamma-delta T cell number [MP:0008347]| abnormal CD4-positive [MP:0008397]| CD25-positive [MP:0008495]| alpha-beta regulatory T cell morphology [MP:0008496]| decreased IgG1 level [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008567]| decreased IgG3 level [MP:0008688]| decreased interferon-gamma secretion [MP:0008897]| decreased interleukin-2 secretion [MP:0010766]

Affected Gene: Card11

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)