URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=29902
Proper Citation: RRID:MMRRC_029902-UCD
Description: Mus musculus with name STOCK Mfn2tm3Dcc/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cell Biology, Developmental Biology, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: kyphosis [MP:0000160]| abnormal cerebellum morphology [MP:0000849]| small cerebellum [MP:0000852]| Purkinje cell degeneration [MP:0000876]| decreased body weight [MP:0001262]| decreased body size [MP:0001265]| hypoactivity [MP:0001402]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| hunched posture [MP:0001505]| impaired righting response [MP:0001523]| impaired limb coordination [MP:0001524]| premature death [MP:0002083]| no abnormal phenotype detected [MP:0002169]| abnormal innervation [MP:0002184]| neurodegeneration [MP:0002229]| decreased vertical activity [MP:0002757]| increased neuron apoptosis [MP:0003203]| abnormal dopaminergic neuron morphology [MP:0003243]| loss of dopaminergic neurons [MP:0003244]| abnormal striatum morphology [MP:0004077]| abnormal axonal transport [MP:0004768]| bradykinesia [MP:0005156]| abnormal axon morphology [MP:0005404]| abnormal mitochondrion morphology [MP:0006035]| abnormal Purkinje cell dendrite morphology [MP:0008572]| abnormal respiratory electron transport chain [MP:0010955]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011087]| neonatal lethality [MP:0011088]| complete penetrance [MP:0011091]
Affected Gene: Mfn2
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)