URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=29869
Proper Citation: RRID:MMRRC_029869-UNC
Description: Mus musculus with name STOCK Onecut1tm1.1Mga/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Cancer, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Models for Human Disease, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection:
Phenotype: pancreas inflammation [MP:0001869]| hemorrhage [MP:0001914]| abnormal pancreas morphology [MP:0001944]| abnormal glucose homeostasis [MP:0002078]| abnormal pancreas physiology [MP:0002693]| pancreas fibrosis [MP:0003334]| pancreas cysts [MP:0003336]| decreased pancreatic beta cell number [MP:0003339]| increased circulating glucose level [MP:0005559]| abnormal pancreatic duct morphology [MP:0009143]| dilated pancreatic duct [MP:0009144]| abnormal pancreatic acinus morphology [MP:0009145]| decreased pancreatic acinar cell number [MP:0009149]| exocrine pancreas atrophy [MP:0009164]| absent pancreatic islets [MP:0009173]| decreased pancreatic alpha cell number [MP:0009177]| abnormal branching involved in pancreas development [MP:0011934]| pancreatic acinar-to-ductal metaplasia [MP:0013221]| calcified pancreas [MP:0014108]
Affected Gene: Onecut1
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)