URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15388
Proper Citation: RRID:MMRRC_015388-UNC
Description: Mus musculus with name STOCK Dicer1tm1Tara/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Developmental Biology, Diabetes, Endocrine Deficiency, Hematology, Immunology and Inflammation, Internal/Organ, Metabolism, Neurobiology, Reproduction, Sensorineural, Virology; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal coat/ hair morphology [MP:0000367]| abnormal hair follicle morphology [MP:0000377]| abnormal thymus morphology [MP:0000703]| decreased body size [MP:0001265]| increased metastatic potential [MP:0001272]| dehydration [MP:0001429]| abnormal thymus involution [MP:0001824]| increased carcinoma incidence [MP:0002038]| premature death [MP:0002083]| abnormal vibrissa morphology [MP:0002098]| abnormal thymus cortex morphology [MP:0002371]| abnormal thymus medulla morphology [MP:0002375]| epidermal cyst [MP:0003414]| abnormal oviduct morphology [MP:0003574]| increased ovarian carcinoma incidence [MP:0003579]| abnormal hair follicle development [MP:0003704]| increased susceptibility to induced arthritis [MP:0003724]| abnormal thymus physiology [MP:0003763]| abnormal positive T cell selection [MP:0004919]| ascites [MP:0005324]| abnormal skin physiology [MP:0005501]| increased apoptosis [MP:0006042]| decreased CD4-positive [MP:0008075]| alpha beta T cell number [MP:0008079]| decreased CD8-positive [MP:0009544]| alpha-beta T cell number [MP:0009931]| abnormal thymus epithelium morphology [MP:0011085]
Affected Gene: Dicer1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)