URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=15198
Proper Citation: RRID:MMRRC_015198-UCD
Description: Mus musculus with name C57BL/6J-Ptpn6m1Btlr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cell Biology, Dermatology, Hematology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix
Phenotype: increased neutrophil cell number [MP:0000219]| ulcerated paws [MP:0000578]| enlarged spleen [MP:0000691]| increased inflammatory response [MP:0001846]| lung inflammation [MP:0001861]| salivary gland inflammation [MP:0001870]| decreased susceptibility to bacterial infection [MP:0002411]| increased IgM level [MP:0002494]| increased erythroid progenitor cell number [MP:0003135]| increased anti-chromatin antibody level [MP:0004829]| decreased mature B cell number [MP:0008211]| abnormal myeloid leukocyte morphology [MP:0008250]| decreased susceptibility to bacterial infection induced morbidity/mortality [MP:0009789]
Affected Gene: Ptpn6
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)