URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=11642
Proper Citation: RRID:MMRRC_011642-UNC
Description: Mus musculus with name B6;129P2-Uchl1tm1Dgen/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection: Deltagen
Phenotype: kyphosis [MP:0000160]| hindlimb paralysis [MP:0000755]| forelimb paralysis [MP:0000756]| motor neuron degeneration [MP:0000938]| abnormal neuromuscular synapse morphology [MP:0001053]| weight loss [MP:0001263]| impaired coordination [MP:0001405]| abnormal gait [MP:0001406]| limb grasping [MP:0001513]| increased thermal nociceptive threshold [MP:0001973]| premature death [MP:0002083]| abnormal PNS synaptic transmission [MP:0002913]| abnormal endplate potential [MP:0002914]| increased synaptic depression [MP:0002916]| decreased paired-pulse facilitation [MP:0002920]| increased coping response [MP:0003063]| astrocytosis [MP:0003354]| decreased neurotransmitter release [MP:0003990]| abnormal miniature endplate potential [MP:0004835]| abnormal synaptic plasticity [MP:0004859]| axon degeneration [MP:0005405]| alpha-synuclein inclusion body [MP:0008493]| decreased grip strength [MP:0010053]
Affected Gene: Uchl1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)