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Organism Name
C57BL/6J-Unc93b13d/Mmucd
RRID:MMRRC_010466-UCD RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=10466

Proper Citation: RRID:MMRRC_010466-UCD

Description: Mus musculus with name C57BL/6J-Unc93b13d/Mmucd from MMRRC.

Species: Mus musculus

Notes: Research areas: Cell Biology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix

Phenotype: abnormal antigen presentation via MHC class I [MP:0001836]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal antigen presentation via MHC class II [MP:0005041]| abnormal dendritic cell morphology [MP:0005461]| abnormal circulating interferon level [MP:0008548]| increased circulating tumor necrosis factor level [MP:0008553]| abnormal tumor necrosis factor secretion [MP:0008556]| decreased interleukin-12b secretion [MP:0008670]| decreased interleukin-6 secretion [MP:0008706]

Affected Gene: Unc93b1

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Data and Source Information

Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/

Source Database: Mutant Mouse Resource and Research Center (MMRRC)