URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=10466
Proper Citation: RRID:MMRRC_010466-UCD
Description: Mus musculus with name C57BL/6J-Unc93b13d/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Cell Biology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix
Phenotype: abnormal antigen presentation via MHC class I [MP:0001836]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal antigen presentation via MHC class II [MP:0005041]| abnormal dendritic cell morphology [MP:0005461]| abnormal circulating interferon level [MP:0008548]| increased circulating tumor necrosis factor level [MP:0008553]| abnormal tumor necrosis factor secretion [MP:0008556]| decreased interleukin-12b secretion [MP:0008670]| decreased interleukin-6 secretion [MP:0008706]
Affected Gene: Unc93b1
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)