URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=9967
Proper Citation: RRID:MMRRC_009967-UCD
Description: Mus musculus with name B6;129X1-Ptk2tm1Lfr/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Dermatology, Developmental Biology, Hematology, Immunology and Inflammation, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection:
Phenotype: abnormal vascular regression [MP:0000364]| decreased hair follicle number [MP:0000379]| abnormal hair follicle orientation [MP:0000383]| sparse hair [MP:0000416]| abnormal hair cycle [MP:0000427]| decreased thymocyte number [MP:0000715]| thin epidermis [MP:0001218]| abnormal blood vessel morphology [MP:0001614]| decreased embryo size [MP:0001698]| disorganized yolk sac vascular plexus [MP:0001723]| hemorrhage [MP:0001914]| abnormal T cell differentiation [MP:0002145]| abnormal vitelline vasculature morphology [MP:0003229]| abnormal capillary morphology [MP:0003658]| decreased double-positive T cell number [MP:0005092]| decreased angiogenesis [MP:0005602]| abnormal vascular endothelial cell morphology [MP:0006055]| decreased keratinocyte proliferation [MP:0009584]| embryonic lethality during organogenesis [MP:0011098]| complete penetrance [MP:0013192]| decreased sebaceous gland number [MP:0013585]
Affected Gene: Ptk2
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)