URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=372
Proper Citation: RRID:MMRRC_000372-UCD
Description: Mus musculus with name 129S-Del(17Hspa1b-Hsp1a)1Dix/Mmucd from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cancer, Cardiovascular, Cell Biology, Developmental Biology, Immunology and Inflammation, Models for Human Disease, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased cell proliferation [MP:0000352]| increased cellular sensitivity to gamma-irradiation [MP:0002007]| increased myocardial infarction size [MP:0003037]| neurofibrillary tangles [MP:0003214]| spontaneous chromosome breakage [MP:0004029]| induced chromosome breakage [MP:0004030]| abnormal cell cycle checkpoint function [MP:0004045]| tau protein deposits [MP:0004250]| decreased mitotic index [MP:0004759]| abnormal enzyme/coenzyme activity [MP:0005584]| abnormal cell physiology [MP:0005621]| abnormal spermatocyte morphology [MP:0006379]| early cellular replicative senescence [MP:0008008]| abnormal DNA repair [MP:0008058]| decreased birth weight [MP:0009674]
Affected Gene: |Hspa1a|Hspa1b
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Source: Mutant Mouse Resource and Research Center (RRID:SCR_002953)
Description: National public repository system for mutant mice. Archives and distributes scientifically valuable spontaneous and induced mutant mouse strains and ES cell lines for use by biomedical research community. Includes breeding/distribution facilities and information coordinating center. Mice strains are cryopreserved, unless live colony must be established. Live mice are supplied from production colony, from colony recovered from cryopreservation, or via micro-injection of cell line into host blastocysts. MMRRC member facilities also develop technologies to improve handling of mutant mice, including advances in assisted reproductive techniques, cryobiology, genetic analysis, phenotyping and infectious disease diagnostics.
URL: http://www.mmrrc.org/
Source Database: Mutant Mouse Resource and Research Center (MMRRC)