URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=199
Proper Citation: RRID:MMRRC_000199-UNC
Description: Mus musculus with name B6;129X1-Prkacatm1Gsm/Mmnc from MMRRC.
Species: Mus musculus
Notes: Research areas: Apoptosis, Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Immunology and Inflammation, Metabolism, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection:
Phenotype: decreased bone mineral density [MP:0000063]| exencephaly [MP:0000914]| abnormal dorsal root ganglion morphology [MP:0000961]| disorganized dorsal root ganglion [MP:0000962]| decreased body weight [MP:0001262]| postnatal growth retardation [MP:0001732]| pericardial edema [MP:0001787]| male infertility [MP:0001925]| postnatal lethality [MP:0002082]| abnormal skeleton development [MP:0002113]| abnormal neural tube morphology [MP:0002151]| asthenozoospermia [MP:0002675]| abnormal bone mineralization [MP:0002896]| abnormal neuron specification [MP:0002948]| decreased urine protein level [MP:0002963]| spina bifida [MP:0003054]| increased osteosarcoma incidence [MP:0003789]| abnormal compact bone morphology [MP:0003797]| abnormal spine curvature [MP:0004174]| abnormal embryonic neuroepithelium morphology [MP:0004261]| abnormal vertebral arch morphology [MP:0004599]| abnormal vertebral column morphology [MP:0004703]| decreased trabecular bone thickness [MP:0009346]| increased osteochondroma incidence [MP:0010079]| increased skeletal tumor incidence [MP:0010280]| abnormal periosteum morphology [MP:0010971]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0011092]| embryonic lethality [MP:0011097]| complete penetrance [MP:0012505]
Affected Gene: Prkaca
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Source: Integrated Animals
Source Database: Mutant Mouse Resource and Research Center (MMRRC)