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Organism Name
B6;129-Npr3tm1Unc/Mmnc
RRID:MMRRC_000016-UNC RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=16

Proper Citation: RRID:MMRRC_000016-UNC

Description: Mus musculus with name B6;129-Npr3tm1Unc/Mmnc from MMRRC.

Species: Mus musculus

Notes: Research areas: ; Mutation Type: Targeted Mutation ; Collection:

Phenotype: delayed bone ossification [MP:0000060]| domed cranium [MP:0000440]| increased body length [MP:0001257]| decreased body weight [MP:0001262]| polydipsia [MP:0001426]| dehydration [MP:0001429]| hunched posture [MP:0001505]| hypotension [MP:0001596]| polyuria [MP:0001762]| reduced fertility [MP:0001921]| abnormal skeleton development [MP:0002113]| increased hematocrit [MP:0002608]| long tail [MP:0002758]| increased circulating alkaline phosphatase level [MP:0002968]| decreased urine osmolality [MP:0002988]| abnormal bone remodeling [MP:0002998]| increased erythrocyte cell number [MP:0003131]| abnormal long bone epiphyseal plate proliferative zone [MP:0003662]| elongated metatarsal bones [MP:0004641]| increased length of long bones [MP:0004695]| elongated vertebral body [MP:0004705]| abnormal osteoclast morphology [MP:0004982]| increased osteoblast cell number [MP:0004988]| increased hemoglobin content [MP:0005564]| abnormal interscapular fat pad morphology [MP:0006320]| decreased brown fat cell lipid droplet size [MP:0009125]| decreased white fat cell size [MP:0009133]| decreased epididymal fat pad weight [MP:0009289]| decreased inguinal fat pad weight [MP:0009293]| decreased interscapular fat pad weight [MP:0009295]| decreased retroperitoneal fat pad weight [MP:0009305]| abnormal blood homeostasis [MP:0009642]| small thoracic cage [MP:0010103]| hypovolemia [MP:0010128]| abnormal bone trabecula morphology [MP:0010867]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0011476]

Affected Gene: Npr3

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)