URL: http://www.addgene.org/22776
Proper Citation: RRID:Addgene_22776
Insert Name: CreERT2
Bacterial Resistance: Ampicillin
Defining Citation: PMID:19903759
Vector Backbone Description: Backbone Marker:Clontech; Backbone Size:6300; Vector Backbone:pMSCV puro; Vector Types:Mammalian Expression, Retroviral, Cre/Lox; Bacterial Resistance:Ampicillin
Comments: Cre-ERT2 contains Cre fused to the ligand-binding domain of a mutated estrogen receptor, which recognizes tamoxifen or its derivative 4-hydroxytamoxifen(4-OHT). This construct permits tamoxifen-dependent Cre activity. Please note that Addgene's sequencing results identified a K183E mutation in the Cre protein sequence. This mutation was not intentional, but was present in the original plasmid and according to the depositing laboratory the plasmid functions as described in the associated publication.
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Source: Addgene