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Organism Name
B6;129-Syn2tm1Pggd Syn3tm1Pggd Syn1tm1Pggd/Mmjax
RRID:MMRRC_041434-JAX RRID Copied  
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Organism Information

URL: https://www.mmrrc.org/catalog/sds.php?mmrrc_id=41434

Proper Citation: RRID:MMRRC_041434-JAX

Description: Mus musculus with name B6;129-Syn2tm1Pggd Syn3tm1Pggd Syn1tm1Pggd/Mmjax from MMRRC.

Species: Mus musculus

Notes: Research areas: Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection:

Phenotype: increased aggression towards mice [MP:0001353]| abnormal social investigation [MP:0001360]| abnormal seizure response to electrical stimulation [MP:0001650]| abnormal emotion/affect behavior [MP:0002572]| abnormal excitatory postsynaptic potential [MP:0002912]| increased synaptic depression [MP:0002916]| delayed CNS synapse formation [MP:0002924]| impaired social transmission of food preference [MP:0002969]| tonic-clonic seizures [MP:0003997]| abnormal synaptic vesicle clustering [MP:0004793]| abnormal brain wave pattern [MP:0004994]| abnormal CNS synapse formation [MP:0004996]| abnormal neurotransmitter secretion [MP:0005445]| environmentally induced seizures [MP:0009358]| abnormal hippocampus pyramidal cell morphology [MP:0009940]| abnormal social investigation [MP:0001360]| abnormal excitatory postsynaptic currents [MP:0002910]| increased synaptic depression [MP:0002916]| abnormal inhibitory postsynaptic currents [MP:0002945]| delayed axon extension [MP:0002946]| impaired social transmission of food preference [MP:0002969]| decreased aggression towards mice [MP:0003863]| tonic-clonic seizures [MP:0003997]| abnormal brain wave pattern [MP:0004994]| environmentally induced seizures [MP:0009358]| increased aggression towards mice [MP:0001353]| abnormal social investigation [MP:0001360]| increased grooming behavior [MP:0001441]| seizures [MP:0002064]| abnormal brain morphology [MP:0002152]| decreased brain weight [MP:0002175]| abnormal CNS synaptic transmission [MP:0002206]| abnormal emotion/affect behavior [MP:0002572]| abnormal short term object recognition memory [MP:0002800]| abnormal neuron morphology [MP:0002882]| abnormal excitatory postsynaptic potential [MP:0002912]| decreased synaptic depression [MP:0002917]| delayed CNS synapse formation [MP:0002924]| tonic-clonic seizures [MP:0003997]| abnormal miniature excitatory postsynaptic currents [MP:0004753]| abnormal synaptic vesicle number [MP:0004792]| abnormal brain wave pattern [MP:0004994]| abnormal CNS synapse formation [MP:0004996]| environmentally induced seizures [MP:0009358]| abnormal hippocampus physiology [MP:0012006]

Affected Gene: Syn1||Syn2||Syn3|

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Data and Source Information

Source: Integrated Animals

Source Database: Mutant Mouse Resource and Research Center (MMRRC)