URL: http://antibodyregistry.org/AB_10674115
Proper Citation: (Antibodies Incorporated Cat# 73-089, RRID:AB_10674115)
Target Antigen: Pan-Shank scaffold protein
Host Organism: mouse
Clonality: monoclonal
Comments:
Applications: IB, ICC, IHC, IP, WB
Validation status: IF or IB (Pass), IB in brain (Pass), IHC in brain (Pass), KO (ND)
This clone is associated with these products: purified (Antibodies Incorporated, Cat# 75-089, RRID:AB_10672418), supernatant (Antibodies Incorporated, Cat# 73-089, RRID:AB_10674115), hybridoma (UC Davis/NIH NeuroMab Facility, Cat# N23B/49, RRID:AB_2877323)
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No rating or validation information has been found for Anti-Pan-Shank Antibody.
Possibly Non-Specific
Extracted Antibody Information: "anti-PanShank (1:1000, Neuromab, RRID: AB_10674115),"
Extracted Specificity Statement: "A panShank antibody was also used to assay overall Shank protein levels, with the caveat that the affinity of the PanShank antibody to different Shank isoforms was unknown. Quantification of the blots showed that infection with control viruses (labeled as GFP or tdT) containing the H1 promoter but not specific shRNAs did not reduce Shank protein levels in the synaptosomal fraction as compared to uninfected cultures, indicating viral infection alone had little effect on the expression of Shank proteins. As expected, infection with shShank1 or shShank3 viruses reduced only the levels of their respective target proteins."
Data was mined by Antibody Watch (https://arxiv.org/pdf/2008.01937.pdf), from PMID:29250591
Source: Antibody Registry
